Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinoma

Prognostic Gene Expression Signature for Patients With Hepatitis C–Related Early-Stage Cirrhosis

(2013) Yujin Hoshida et al.   GASTROENTEROLOGY

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibrosis-dependent mechanisms of hepatocarcinogenesis

(2012) David Y. Zhang et al.   HEPATOLOGY

Epidermal growth factor receptor and HER-3 restrict cell response to sorafenib in hepatocellular carcinoma cells

(2012) Marie-José Blivet-Van Eggelpoël et al.   JOURNAL OF HEPATOLOGY

Heparin-binding epidermal growth factor-like growth factor suppresses experimental liver fibrosis in mice

(2012) Guangcun Huang et al.   LABORATORY INVESTIGATION

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Carriage of the EGF rs4444903 A>G functional polymorphism associates with disease progression in chronic HBV infection

(2011) S. Cmet et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Association between the epidermal growth factor rs4444903 G/G genotype and advanced fibrosis at a young age in chronic hepatitis C

(2011) Edmondo Falleti et al.   CYTOKINE

EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy

(2011) Joachim Lupberger et al.   NATURE MEDICINE

Hepatocellular Carcinoma

(2011) Hashem B. El-Serag   NEW ENGLAND JOURNAL OF MEDICINE

Mouse model of carbon tetrachloride induced liver fibrosis: Histopathological changes and expression of CD133 and epidermal growth factor

(2010) Tsutomu Fujii et al.   BMC GASTROENTEROLOGY

The Epidermal Growth Factor Receptor: A Link Between Inflammation and Liver Cancer

(2009) Carmen Berasain et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Targeting liver fibrosis: Strategies for development and validation of antifibrotic therapies

(2009) Yury Popov et al.   HEPATOLOGY

Bile Acid-induced Epidermal Growth Factor Receptor Activation in Quiescent Rat Hepatic Stellate Cells Can Trigger Both Proliferation and Apoptosis

(2009) Annika Sommerfeld et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endocytosis and intracellular trafficking of ErbBs

(2008) Alexander Sorkin et al.   EXPERIMENTAL CELL RESEARCH

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Incidence of Hepatocellular Carcinoma and Associated Risk Factors in Hepatitis C-Related Advanced Liver Disease

(2008) Anna S. Lok et al.   GASTROENTEROLOGY

The epidermal growth factor receptor ligand amphiregulin participates in the development of mouse liver fibrosis

(2008) Maria J. Perugorria et al.   HEPATOLOGY

Epidermal Growth Factor Gene Functional Polymorphism and the Risk of Hepatocellular Carcinoma in Patients With Cirrhosis

(2008) Kenneth K. Tanabe et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Liver cirrhosis

(2008) Detlef Schuppan et al.   LANCET

Gene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma

(2008) Yujin Hoshida et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS