Important Role of FTO in the Survival of Rare Panresistant Triple-Negative Inflammatory Breast Cancer Cells Facing a Severe Metabolic Challenge

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

(2015) Melina Claussnitzer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Synthesis of a FTO Inhibitor with Anticonvulsant Activity

(2014) Guanqun Zheng et al.   ACS Chemical Neuroscience

Single nucleotide polymorphisms of the FTO gene and cancer risk: an overview

(2014) Marta Elena Hernández-Caballero et al.   MOLECULAR BIOLOGY REPORTS

Clonal evolution in breast cancer revealed by single nucleus genome sequencing

(2014) Yong Wang et al.   NATURE

Obesity-associated variants within FTO form long-range functional connections with IRX3

(2014) Scott Smemo et al.   NATURE

Highly Adaptable Triple-Negative Breast Cancer Cells as a Functional Model for Testing Anticancer Agents

(2014) Balraj Singh et al.   PLoS One

Uncovering the Molecular Secrets of Inflammatory Breast Cancer Biology: An Integrated Analysis of Three Distinct Affymetrix Gene Expression Datasets

(2013) S. J. Van Laere et al.   CLINICAL CANCER RESEARCH

Genome-wide association studies identify four ER negative–specific breast cancer risk loci

(2013) Montserrat Garcia-Closas et al.   NATURE GENETICS

Role for the obesity-related FTO gene in the cellular sensing of amino acids

(2013) P. Gulati et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Systematic Mapping Approach of 16q12.2/FTO and BMI in More Than 20,000 African Americans Narrows in on the Underlying Functional Variation: Results from the Population Architecture using Genomics and Epidemiology (PAGE) Study

(2013) Ulrike Peters et al.   PLoS Genetics

FTO levels affect RNA modification and the transcriptome

(2012) Tea Berulava et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

The impact of intronic single nucleotide polymorphisms and ethnic diversity for studies on the obesity geneFTO

(2012) J. A. Jacobsson et al.   Obesity Reviews

Selection of Metastatic Breast Cancer Cells Based on Adaptability of Their Metabolic State

(2012) Balraj Singh et al.   PLoS One

Micro-Scale Genomic DNA Copy Number Aberrations as Another Means of Mutagenesis in Breast Cancer

(2012) Hann-Hsiang Chao et al.   PLoS One

Cloning and characterization of chicken fat mass and obesity associated (Fto) gene: fasting affects Fto expression

(2011) A. Tiwari et al.   DOMESTIC ANIMAL ENDOCRINOLOGY

AACR Centennial Series: The Biology of Cancer Metastasis: Historical Perspective

(2010) J. E. Talmadge et al.   CANCER RESEARCH

Evaluation of a CXCR4 antagonist in a xenograft mouse model of inflammatory breast cancer

(2010) Balraj Singh et al.   CLINICAL & EXPERIMENTAL METASTASIS

Cut-like Homeobox 1 (CUX1) Regulates Expression of the Fat Mass and Obesity-associated and Retinitis Pigmentosa GTPase Regulator-interacting Protein-1-like (RPGRIP1L) Genes and Coordinates Leptin Receptor Signaling

(2010) George Stratigopoulos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

On Getting There from Here

(2010) S. L. McKnight   SCIENCE

Modulator recognition factor-2 regulates triglyceride metabolism in adipocytes

(2009) Takahiro Yamakawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inactivation of the Fto gene protects from obesity

(2009) Julia Fischer et al.   NATURE

The Obesity Gene, FTO, Is of Ancient Origin, Up-Regulated during Food Deprivation and Expressed in Neurons of Feeding-Related Nuclei of the Brain

(2008) Robert Fredriksson et al.   ENDOCRINOLOGY