Role for the obesity-related FTO gene in the cellular sensing of amino acids

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

Leucyl-tRNA Synthetase Is an Intracellular Leucine Sensor for the mTORC1-Signaling Pathway

(2012) Jung Min Han et al.   CELL

Leucyl-tRNA Synthetase Controls TORC1 via the EGO Complex

(2012) Grégory Bonfils et al.   MOLECULAR CELL

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Overexpression of Fto leads to increased food intake and results in obesity

(2010) Chris Church et al.   NATURE GENETICS

Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats

(2010) Yi-Chun Loraine Tung et al.   PLoS One

The genetics of obesity: FTO leads the way

(2010) Katherine A. Fawcett et al.   TRENDS IN GENETICS

Loss-of-Function Mutation in the Dioxygenase-Encoding FTO Gene Causes Severe Growth Retardation and Multiple Malformations

(2009) Sarah Boissel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

In search of an “autophagomometer”

(2009) David C. Rubinsztein et al.   Autophagy

Inactivation of the Fto gene protects from obesity

(2009) Julia Fischer et al.   NATURE

SUnSET, a nonradioactive method to monitor protein synthesis

(2009) Enrico K Schmidt et al.   NATURE METHODS

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Obesity,FTOGene Variant, and Energy Intake in Children

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Variation in the FTO Gene Influences Food Intake but not Energy Expenditure

(2008) A. Haupt et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO

(2008) Guifang Jia et al.   FEBS LETTERS

The FTO gene and measured food intake in children

(2008) J Wardle et al.   INTERNATIONAL JOURNAL OF OBESITY

Obesity Associated Genetic Variation inFTOIs Associated with Diminished Satiety

(2008) Jane Wardle et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

An Obesity-AssociatedFTOGene Variant and Increased Energy Intake in Children

(2008) Joanne E. Cecil et al.   NEW ENGLAND JOURNAL OF MEDICINE

Polymorphisms of theFTOGene Are Associated With Variation in Energy Intake, but not Energy Expenditure

(2008) John R. Speakman et al.   Obesity