The impact of intronic single nucleotide polymorphisms and ethnic diversity for studies on the obesity geneFTO

Genetic determinants of common obesity and their value in prediction

(2012) Ruth J.F. Loos   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Gene-Diet Interactions in Childhood Obesity

(2012) William S. Garver   CURRENT GENOMICS

Genome wide analysis reveals association of a FTO gene variant with epigenetic changes

(2012) Markus Sällman Almén et al.   GENOMICS

Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations

(2012) Yukinori Okada et al.   NATURE GENETICS

Meta-analysis identifies common variants associated with body mass index in east Asians

(2012) Wanqing Wen et al.   NATURE GENETICS

A genome-wide association meta-analysis identifies new childhood obesity loci

(2012)   NATURE GENETICS

Associations of Variants inFTOand NearMC4RWith Obesity Traits in South Asian Indians

(2012) Senthil K. Vasan et al.   Obesity

Appetite regulation genes are associated with body mass index in black South African adolescents: a genetic association study

(2012) Zané Lombard et al.   BMJ Open

Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women

(2012) Caroline S. Fox et al.   PLoS Genetics

Association of the FTO rs9939609 polymorphism with obesity in Roma/Gypsy population

(2011) Soňa Mačeková et al.   AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY

Association of FTO rs17817449 SNP with obesity and associated physiological parameters in a north Indian population

(2011) Jai Prakash et al.   ANNALS OF HUMAN BIOLOGY

rs9939609 in the FTO Gene is Associated with Obesity but not with Several Biochemical Parameters in Sardinian Obese Children

(2011) Patrizia Zavattari et al.   ANNALS OF HUMAN GENETICS

From GWAS to biology: lessons from FTO

(2011) Yi-Chun Loraine Tung et al.   Annals of the New York Academy of Sciences

Fto colocalizes with a satiety mediator oxytocin in the brain and upregulates oxytocin gene expression

(2011) Pawel K. Olszewski et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anti-inflammatory Profile of FTO Gene Expression in Adipose Tissues From Morbidly Obese Women

(2011) Ximena Terra et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Heterozygous Mutations Causing Partial Prohormone Convertase 1 Deficiency Contribute to Human Obesity

(2011) J. W. M. Creemers et al.   DIABETES

Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations

(2011) R Dorajoo et al.   INTERNATIONAL JOURNAL OF OBESITY

Study of eight GWAS-identified common variants for association with obesity-related indices in Chinese children at puberty

(2011) J Wang et al.   INTERNATIONAL JOURNAL OF OBESITY

Recapitulation of genome-wide association studies on body mass index in the Korean population

(2011) K W Hong et al.   INTERNATIONAL JOURNAL OF OBESITY

Histone Deacetylase 9 Is a Negative Regulator of Adipogenic Differentiation

(2011) Tapan K. Chatterjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Associations between a Single Nucleotide Polymorphism of theFTOGene (rs9939609) and Obesity-Related Characteristics over Time during Puberty in a Dutch Children Cohort

(2011) Femke Rutters et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

In vitro DNA-binding profile of transcription factors: methods and new insights

(2011) Jinke Wang et al.   JOURNAL OF ENDOCRINOLOGY

Common variants of FTO and the risk of obesity and type 2 diabetes in Indians

(2011) Ganesh Chauhan et al.   JOURNAL OF HUMAN GENETICS

The rs7204609 Polymorphism in the Fat Mass and Obesity-Associated Gene is Positively Associated With Central Obesity and Microalbuminuria in Patients With Type 2 Diabetes From Southern Brazil

(2011) Thais Steemburgo et al.   JOURNAL OF RENAL NUTRITION

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

(2011) Tuomas O Kilpeläinen et al.   NATURE GENETICS

The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men

(2011) Christian Benedict et al.   NEUROBIOLOGY OF AGING

Common Variants in FTO, MC4R, TMEM18, PRL, AIF1, and PCSK1 Show Evidence of Association With Adult Obesity in the Greek Population

(2011) Konstantinos Rouskas et al.   Obesity

Interaction of FTO and Physical Activity Level on Adiposity in African-American and European-American Adults: The ARIC Study

(2011) Ellen W. Demerath et al.   Obesity

Genome-Wide Association of BMI in African Americans

(2011) Maggie C.Y. Ng et al.   Obesity

Role of BMI-Associated Loci Identified in GWAS Meta-Analyses in the Context of Common Childhood Obesity in European Americans

(2011) Jianhua Zhao et al.   Obesity

FTO mRNA Expression in Extremely Obese and Type 2 Diabetic Human Omental and Subcutaneous Adipose Tissues

(2011) Belgin Süsleyici-Duman et al.   OBESITY SURGERY

FTO gene is related to obesity in Chilean Amerindian children and impairs HOMA-IR in prepubertal girls

(2011) Benilde Riffo et al.   PEDIATRIC DIABETES

Association between the FTO gene and overweight in Japanese children and adolescents

(2011) Masayuki Okuda et al.   PEDIATRIC DIABETES

Fto immunoreactivity is widespread in the rodent brain and abundant in feeding-related sites, but the number of Fto-positive cells is not affected by changes in energy balance

(2011) Pawel K. Olszewski et al.   PHYSIOLOGY & BEHAVIOR

Allele-Specific, Age-Dependent and BMI-Associated DNA Methylation of Human MCHR1

(2011) Stefanie Stepanow et al.   PLoS One

A Genome-Wide Association Study on Obesity and Obesity-Related Traits

(2011) Kai Wang et al.   PLoS One

Detailed Analysis of Variants in FTO in Association with Body Composition in a Cohort of 70-Year-Olds Suggests a Weakened Effect among Elderly

(2011) Josefin A. Jacobsson et al.   PLoS One

Genome-Wide Population-Based Association Study of Extremely Overweight Young Adults – The GOYA Study

(2011) Lavinia Paternoster et al.   PLoS One

Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children

(2011) Tuomas O. Kilpeläinen et al.   PLOS MEDICINE

The obesity-associated Fto gene is a transcriptional coactivator

(2010) Qiong Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The common rs9939609 variant of the fat mass and obesity-associated gene is associated with obesity risk in children and adolescents of Beijing, China

(2010) Bo Xi et al.   BMC Medical Genetics

Variant rs9939609 in the FTO gene is associated with body mass index among Chinese children

(2010) Hongyun Fang et al.   BMC Medical Genetics

FTO Genetic Variation and Association With Obesity in West Africans and African Americans

(2010) A. Adeyemo et al.   DIABETES

A genetic variation in the fat mass- and obesity-associated gene is associated with obesity and newly diagnosed type 2 diabetes in a Chinese population

(2010) Xiangyang Li et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Association of the Common Fat Mass and Obesity Associated (FTO) Gene Polymorphism with Obesity in a Japanese Population

(2010) Shigeru KARASAWA et al.   ENDOCRINE JOURNAL

The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels

(2010) Tea Berulava et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Regulation ofFTOandFTMExpression During Human Preadipocyte Differentiation

(2010) D. Tews et al.   HORMONE AND METABOLIC RESEARCH

Natural selection at genomic regions associated with obesity and type-2 diabetes: East Asians and sub-Saharan Africans exhibit high levels of differentiation at type-2 diabetes regions

(2010) Yann C. Klimentidis et al.   HUMAN GENETICS

Fine mapping of the association with obesity at the FTO locus in African-derived populations

(2010) Mohamed T. Hassanein et al.   HUMAN MOLECULAR GENETICS

Genome-wide association of anthropometric traits in African- and African-derived populations

(2010) S. J. Kang et al.   HUMAN MOLECULAR GENETICS

Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort

(2010) M R Wing et al.   INTERNATIONAL JOURNAL OF OBESITY

Cut-like Homeobox 1 (CUX1) Regulates Expression of the Fat Mass and Obesity-associated and Retinitis Pigmentosa GTPase Regulator-interacting Protein-1-like (RPGRIP1L) Genes and Coordinates Leptin Receptor Signaling

(2010) George Stratigopoulos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Obesity Susceptibility Genetic Variants Identified from Recent Genome-Wide Association Studies: Implications in a Chinese Population

(2010) Chloe Y. Y. Cheung et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Crystal structure of the FTO protein reveals basis for its substrate specificity

(2010) Zhifu Han et al.   NATURE

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

(2010) Iris M Heid et al.   NATURE GENETICS

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Overexpression of Fto leads to increased food intake and results in obesity

(2010) Chris Church et al.   NATURE GENETICS

Obesity-Associated Cognitive Decline: Excess Weight Affects More than the Waistline

(2010) Ronald A. Cohen   NEUROEPIDEMIOLOGY

Association ofFTOGene Variants With Adiposity in African-American Adolescents

(2010) Sureka Bollepalli et al.   Obesity

Genome-Wide Association Study of Anthropometric Traits and Evidence of Interactions With Age and Study Year in Filipino Women

(2010) Damien C. Croteau-Chonka et al.   Obesity

Meta-analysis Added Power to Identify Variants in FTO Associated With Type 2 Diabetes and Obesity in the Asian Population

(2010) Yun Liu et al.   Obesity

Effects of theFTOGene on Lifestyle Intervention Studies in Children

(2010) Tara Rendo et al.   Obesity Facts

Risk of Type 2 Diabetes and Obesity Is Differentially Associated with Variation in FTO in Whites and African-Americans in the ARIC Study

(2010) Jan Bressler et al.   PLoS One

Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus

(2010) Christopher G. Bell et al.   PLoS One

The Fat Mass and Obesity Associated Gene FTO Functions in the Brain to Regulate Postnatal Growth in Mice

(2010) Xue Gao et al.   PLoS One

A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly

(2010) A. J. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Where to go with FTO?

(2010) Rachel Larder et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The genetics of obesity: FTO leads the way

(2010) Katherine A. Fawcett et al.   TRENDS IN GENETICS

Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups

(2010) André Scherag et al.   PLoS Genetics

A loop matters for FTO substrate selection

(2010) Zhifu Han et al.   Protein & Cell

Postprandial responses in hunger and satiety are associated with the rs9939609 single nucleotide polymorphism in FTO

(2009) Marcel den Hoed et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The FTO gene rs9939609 obesity-risk allele and loss of control over eating

(2009) Marian Tanofsky-Kraff et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Physical activity attenuates the body mass index–increasing influence of genetic variation in the FTO gene

(2009) Karani S Vimaleswaran et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Fat and carbohydrate intake modify the association between genetic variation in the FTO genotype and obesity

(2009) Emily Sonestedt et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

FTOgene variation and measures of body mass in an African population

(2009) Branwen J Hennig et al.   BMC Medical Genetics

The common FTOvariant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924

(2009) Josefin A Jacobsson et al.   BMC Medical Genetics

Regulation and Function of FTO mRNA Expression in Human Skeletal Muscle and Subcutaneous Adipose Tissue

(2009) L. G. Grunnet et al.   DIABETES

Association of the FTO gene with obesity and the metabolic syndrome is independent of the IRS-2 gene in the female population of Southern France

(2009) R. Attaoua et al.   DIABETES & METABOLISM

Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany

(2009) Anke Tönjes et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

FTO – Friend or Foe?

(2009) D. Tews et al.   HORMONE AND METABOLIC RESEARCH

Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study

(2009) Maria R. Wing et al.   HUMAN GENETICS

Upstream transcription factor 1 influences plasma lipid and metabolic traits in mice

(2009) Sulin Wu et al.   HUMAN MOLECULAR GENETICS

Common body mass index-associated variants confer risk of extreme obesity

(2009) Chris Cotsapas et al.   HUMAN MOLECULAR GENETICS

Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden

(2009) Frida Renström et al.   HUMAN MOLECULAR GENETICS

Life course variations in the associations between FTO and MC4R gene variants and body size

(2009) R. Hardy et al.   HUMAN MOLECULAR GENETICS

Prognostic significance of FTO genotype in the development of obesity in Japanese: the J-SHIPP study

(2009) Y Tabara et al.   INTERNATIONAL JOURNAL OF OBESITY

FTO Genotype Is Associated with Body Mass Index after the Age of Seven Years But Not with Energy Intake or Leisure-Time Physical Activity

(2009) Maarit Hakanen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Combined effects of MC4R and FTO common genetic variants on obesity in European general populations

(2009) Stéphane Cauchi et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Effect of an FTO polymorphism on fat mass, obesity, and type 2 diabetes mellitus in the French MONICA Study

(2009) Vanessa Legry et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Role of Jhdm2a in regulating metabolic gene expression and obesity resistance

(2009) Keisuke Tateishi et al.   NATURE

Inactivation of the Fto gene protects from obesity

(2009) Julia Fischer et al.   NATURE

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations

(2009) David Meyre et al.   NATURE GENETICS

Gene–environment interactions and obesity—Further aspects of genomewide association studies

(2009) Camilla H. Andreasen et al.   NUTRITION

The Common Variant in theFTOGene Did Not Modify the Effect of Lifestyle Changes on Body Weight: The Finnish Diabetes Prevention Study

(2009) Tiina J. Lappalainen et al.   Obesity

Subcutaneous and Visceral Adipose Tissue FTO Gene Expression and Adiposity, Insulin Action, Glucose Metabolism, and Inflammatory Adipokines in Type 2 Diabetes Mellitus and in Health

(2009) Katherine Samaras et al.   OBESITY SURGERY

Dietary Energy Density Affects Fat Mass in Early Adolescence and Is Not Modified by FTO Variants

(2009) Laura Johnson et al.   PLoS One

Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution

(2009) Cecilia M. Lindgren et al.   PLoS Genetics

A Mouse Model for the Metabolic Effects of the Human Fat Mass and Obesity Associated FTO Gene

(2009) Chris Church et al.   PLoS Genetics

Regulation of Fto/Ftm gene expression in mice and humans

(2008) George Stratigopoulos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Physical Activity and the Association of Common FTO Gene Variants With Body Mass Index and Obesity

(2008) Evadnie Rampersaud et al.   ARCHIVES OF INTERNAL MEDICINE

Association of Morbid Obesity With FTO and INSIG2 Allelic Variants

(2008) Xin Chu   ARCHIVES OF SURGERY

Major gender difference in association of FTO gene variant among severely obese children with obesity and obesity related phenotypes

(2008) Josefin A. Jacobsson et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

FTO gene SNPs associated with extreme obesity in cases, controls and extremely discordant sister pairs

(2008) R Arlen Price et al.   BMC Medical Genetics

Variant rs9939609 in theFTOgene is associated with obesity in an adult population from Spain

(2008) José L. González-Sánchez et al.   CLINICAL ENDOCRINOLOGY

Fat Mass-and Obesity-Associated (FTO) Gene Variant Is Associated With Obesity: Longitudinal Analyses in Two Cohort Studies and Functional Test

(2008) L. Qi et al.   DIABETES

Association of FTO With Obesity-Related Traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort

(2008) A. F. Marvelle et al.   DIABETES

Common Variation in the Fat Mass and Obesity-Associated (FTO) Gene Confers Risk of Obesity and Modulates BMI in the Chinese Population

(2008) Y.-C. Chang et al.   DIABETES

Genetic Variants of FTO Influence Adiposity, Insulin Sensitivity, Leptin Levels, and Resting Metabolic Rate in the Quebec Family Study

(2008) R. Do et al.   DIABETES

Implication of Genetic Variants Near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in Type 2 Diabetes and Obesity in 6,719 Asians

(2008) M. C.Y. Ng et al.   DIABETES

FTO Variants Are Associated With Obesity in the Chinese and Malay Populations in Singapore

(2008) J. T. Tan et al.   DIABETES

Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans

(2008) N. Klöting et al.   DIABETOLOGIA

The Obesity Gene, FTO, Is of Ancient Origin, Up-Regulated during Food Deprivation and Expressed in Neurons of Feeding-Related Nuclei of the Brain

(2008) Robert Fredriksson et al.   ENDOCRINOLOGY

Variation in the FTO Gene Influences Food Intake but not Energy Expenditure

(2008) A. Haupt et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO

(2008) Guifang Jia et al.   FEBS LETTERS

Replication of the association of common rs9939609 variant of FTO with increased BMI in an Australian adult twin population but no evidence for gene by environment (G × E) interaction

(2008) B K Cornes et al.   INTERNATIONAL JOURNAL OF OBESITY

The FTO gene and measured food intake in children

(2008) J Wardle et al.   INTERNATIONAL JOURNAL OF OBESITY

Variations in the FTO gene are associated with severe obesity in the Japanese

(2008) Kikuko Hotta et al.   JOURNAL OF HUMAN GENETICS

Discovery and verification of functional single nucleotide polymorphisms in regulatory genomic regions: Current and developing technologies

(2008) B CHORLEY et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Common variants near MC4R are associated with fat mass, weight and risk of obesity

(2008) Ruth J F Loos et al.   NATURE GENETICS

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

(2008) Gudmar Thorleifsson et al.   NATURE GENETICS

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

(2008) Cristen J Willer et al.   NATURE GENETICS

An Obesity-AssociatedFTOGene Variant and Increased Energy Intake in Children

(2008) Joanne E. Cecil et al.   NEW ENGLAND JOURNAL OF MEDICINE

FTOPolymorphisms Are Associated With Obesity but Not Diabetes Risk in Postmenopausal Women

(2008) Yiqing Song et al.   Obesity

TheFTOGene and Obesity in a Large Eastern European Population Sample: The HAPIEE Study

(2008) Jaroslav A. Hubacek et al.   Obesity

Polymorphisms of theFTOGene Are Associated With Variation in Energy Intake, but not Energy Expenditure

(2008) John R. Speakman et al.   Obesity

Association of the FTO Gene With BMI

(2008) Steven C. Hunt et al.   Obesity

TheFTOGene Is Associated With Adulthood Obesity in the Mexican Population

(2008) Marisela Villalobos-Comparán et al.   Obesity

Replication of Genetic Effects ofFTOPolymorphisms on BMI in a Korean Population

(2008) Seong W. Cha et al.   Obesity

FTO: the first gene contributing to common forms of human obesity

(2008) R. J. F. Loos et al.   Obesity Reviews

The FTO Obesity Gene. Genotyping and Gene Expression Analysis in Morbidly Obese Patients

(2008) Carina Zabena et al.   OBESITY SURGERY

Association Analysis of the FTO Gene with Obesity in Children of Caucasian and African Ancestry Reveals a Common Tagging SNP

(2008) Struan F. A. Grant et al.   PLoS One

FTO Gene Associated Fatness in Relation to Body Fat Distribution and Metabolic Traits throughout a Broad Range of Fatness

(2008) Sofia I. I. Kring et al.   PLoS One

Variants in the FTO gene are associated with common obesity in the Belgian population

(2007) Armand Peeters et al.   MOLECULAR GENETICS AND METABOLISM