Therapeutic Intervention in Multiple Sclerosis with Alpha B-Crystallin: A Randomized Controlled Phase IIa Trial

Demyelination during multiple sclerosis is associated with combined activation of microglia/macrophages by IFN-γ and alpha B-crystallin

(2014) Malika Bsibsi et al.   ACTA NEUROPATHOLOGICA

Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation

(2014) A. David et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alpha-B-Crystallin Induces an Immune-Regulatory and Antiviral Microglial Response in Preactive Multiple Sclerosis Lesions

(2013) Malika Bsibsi et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

How Do Immune Cells Support and Shape the Brain in Health, Disease, and Aging?

(2013) M. Schwartz et al.   JOURNAL OF NEUROSCIENCE

α-Crystallin protects RGC survival and inhibits microglial activation after optic nerve crush

(2013) Nan Wu et al.   LIFE SCIENCES

Activation of an immune-regulatory macrophage response and inhibition of lung inflammation in a mouse model of COPD using heat-shock protein alpha B-crystallin-loaded PLGA microparticles

(2012) Johannes M. van Noort et al.   BIOMATERIALS

Mechanisms in the Development of Multiple Sclerosis Lesions: Reconciling Autoimmune and Neurodegenerative Factors

(2012) Johannes M. van Noort et al.   CNS & Neurological Disorders-Drug Targets

Chaperone Activity of Small Heat Shock Proteins Underlies Therapeutic Efficacy in Experimental Autoimmune Encephalomyelitis

(2012) Michael P. Kurnellas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Beneficial Effects of  B-Crystallin in Spinal Cord Contusion Injury

(2012) A. Klopstein et al.   JOURNAL OF NEUROSCIENCE

Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria

(2011) Chris H. Polman et al.   ANNALS OF NEUROLOGY

Oxidative damage in multiple sclerosis lesions

(2011) L. Haider et al.   BRAIN

Functional rescue of experimental ischemic optic neuropathy with αB-crystallin

(2011) S Pangratz-Fuehrer et al.   EYE

Alpha-Crystallin Promotes Rat Axonal Regeneration Through Regulation of RhoA/Rock/Cofilin/MLC Signaling Pathways

(2011) Yan Hua Wang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Systemic augmentation of αB-crystallin provides therapeutic benefit twelve hours post-stroke onset via immune modulation

(2011) Ahmet Arac et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

αB-Crystallin Is a Target for Adaptive Immune Responses and a Trigger of Innate Responses in Preactive Multiple Sclerosis Lesions

(2010) Johannes M. van Noort et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Alpha-Crystallin Promotes Rat Retinal Neurite Growth on Myelin Substrates in vitro

(2010) Yan Hua Wang et al.   OPHTHALMIC RESEARCH

α-Crystallin Protected Axons from Optic Nerve Degeneration After Crushing in Rats

(2008) Xi Ying et al.   JOURNAL OF MOLECULAR NEUROSCIENCE