Demyelination during multiple sclerosis is associated with combined activation of microglia/macrophages by IFN-γ and alpha B-crystallin

Microglial priming in neurodegenerative disease

(2014) V. Hugh Perry et al.   Nature Reviews Neurology

Iron and neurodegeneration in the multiple sclerosis brain

(2013) Simon Hametner et al.   ANNALS OF NEUROLOGY

FAT10ylation as a signal for proteasomal degradation

(2013) Gunter Schmidtke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cortical grey matter demyelination can be induced by elevated pro-inflammatory cytokines in the subarachnoid space of MOG-immunized rats

(2013) Christopher Gardner et al.   BRAIN

Disease-specific molecular events in cortical multiple sclerosis lesions

(2013) Marie Therese Fischer et al.   BRAIN

IFN-γ-dependent activation of the brain’s choroid plexus for CNS immune surveillance and repair

(2013) Gilad Kunis et al.   BRAIN

Synergistic Activation of Inflammatory Cytokine Genes by Interferon-γ-Induced Chromatin Remodeling and Toll-like Receptor Signaling

(2013) Yu Qiao et al.   IMMUNITY

Alpha-B-Crystallin Induces an Immune-Regulatory and Antiviral Microglial Response in Preactive Multiple Sclerosis Lesions

(2013) Malika Bsibsi et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

α-Crystallin protects RGC survival and inhibits microglial activation after optic nerve crush

(2013) Nan Wu et al.   LIFE SCIENCES

Feasibility of the Use of Combinatorial Chemokine Arrays to Study Blood and CSF in Multiple Sclerosis

(2013) Keith R. Edwards et al.   PLoS One

Interferon Gamma Receptor: The Beginning of the Journey

(2013) Cédric M. Blouin et al.   Frontiers in Immunology

Reductive Stress Linked to Small HSPs, G6PD, and Nrf2 Pathways in Heart Disease

(2012) Alison C. Brewer et al.   ANTIOXIDANTS & REDOX SIGNALING

Activation of an immune-regulatory macrophage response and inhibition of lung inflammation in a mouse model of COPD using heat-shock protein alpha B-crystallin-loaded PLGA microparticles

(2012) Johannes M. van Noort et al.   BIOMATERIALS

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

(2012) Marie T. Fischer et al.   BRAIN

Mechanisms in the Development of Multiple Sclerosis Lesions: Reconciling Autoimmune and Neurodegenerative Factors

(2012) Johannes M. van Noort et al.   CNS & Neurological Disorders-Drug Targets

A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

(2012) Masahiro Yamamoto et al.   IMMUNITY

Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation

(2012) Jack van Horssen et al.   Journal of Neuroinflammation

Beneficial Effects of  B-Crystallin in Spinal Cord Contusion Injury

(2012) A. Klopstein et al.   JOURNAL OF NEUROSCIENCE

Stable Antigen Is Most Effective for Eliciting CD8+T-Cell Responses after DNA Vaccination and Infection with Recombinant Vaccinia VirusIn Vivo

(2012) Christopher Schliehe et al.   JOURNAL OF VIROLOGY

Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin

(2012) Wei Shao et al.   NATURE

Progressive multiple sclerosis: pathology and pathogenesis

(2012) Hans Lassmann et al.   Nature Reviews Neurology

αB-Crystallin is Expressed in Myelinating Oligodendrocytes of the Developing and Adult Avian Retina

(2012) Ji Young Kim et al.   NEUROCHEMICAL RESEARCH

Study ofαB-Crystallin Expression in Gerbil BCAO Model of Transient Global Cerebral Ischemia

(2012) Ting Li et al.   Oxidative Medicine and Cellular Longevity

GBP5 Promotes NLRP3 Inflammasome Assembly and Immunity in Mammals

(2012) A. R. Shenoy et al.   SCIENCE

Alpha B-crystallin prevents the arrhythmogenic effects of particulate matter isolated from ambient air by attenuating oxidative stress

(2012) Hyelim Park et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

αB-Crystallin Improves Murine Cardiac Function and Attenuates Apoptosis in Human Endothelial Cells Exposed to Ischemia-Reperfusion

(2011) Jeffrey B. Velotta et al.   ANNALS OF THORACIC SURGERY

Strategies for aggregating gene expression data: The collapseRows R function

(2011) Jeremy A Miller et al.   BMC BIOINFORMATICS

Oxidative damage in multiple sclerosis lesions

(2011) L. Haider et al.   BRAIN

Functional rescue of experimental ischemic optic neuropathy with αB-crystallin

(2011) S Pangratz-Fuehrer et al.   EYE

Behavioral Defects in Chaperone-Deficient Alzheimer's Disease Model Mice

(2011) Juhi Ojha et al.   PLoS One

Systemic augmentation of αB-crystallin provides therapeutic benefit twelve hours post-stroke onset via immune modulation

(2011) Ahmet Arac et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Family of IFN- -Inducible 65-kD GTPases Protects Against Bacterial Infection

(2011) B.-H. Kim et al.   SCIENCE

Meningeal T cells associate with diffuse axonal loss in multiple sclerosis spinal cords

(2010) Géraldine Androdias et al.   ANNALS OF NEUROLOGY

Glycogen synthase kinase 3: A point of convergence for the host inflammatory response

(2010) Huizhi Wang et al.   CYTOKINE

αB-Crystallin Is a Target for Adaptive Immune Responses and a Trigger of Innate Responses in Preactive Multiple Sclerosis Lesions

(2010) Johannes M. van Noort et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Suppression of GFAP toxicity by αB-crystallin in mouse models of Alexander disease

(2009) Tracy L. Hagemann et al.   HUMAN MOLECULAR GENETICS

Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms

(2009) Xiaoyu Hu et al.   IMMUNOLOGICAL REVIEWS

αA-crystallin and αB-crystallin, newly identified interaction proteins of protease-activated receptor-2, rescue astrocytes from C2-ceramide- and staurosporine-induced cell death

(2009) Rongyu Li et al.   JOURNAL OF NEUROCHEMISTRY

The Ubiquitin-Like Protein FAT10 Mediates NF- B Activation

(2009) P. Gong et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Allergen Challenge Induces Ifng Dependent GTPases in the Lungs as Part of a Th1 Transcriptome Response in a Murine Model of Allergic Asthma

(2009) Nilesh Dharajiya et al.   PLoS One

Severe oxidative damage in multiple sclerosis lesions coincides with enhanced antioxidant enzyme expression

(2008) J. van Horssen et al.   FREE RADICAL BIOLOGY AND MEDICINE

α-Crystallin Protected Axons from Optic Nerve Degeneration After Crushing in Rats

(2008) Xi Ying et al.   JOURNAL OF MOLECULAR NEUROSCIENCE