[6]-Shogaol inhibits growth and induces apoptosis of non-small cell lung cancer cells by directly regulating Akt1/2

Direct Targeting of MEK1/2 and RSK2 by Silybin Induces Cell-Cycle Arrest and Inhibits Melanoma Cell Growth

(2013) M.-H. Lee et al.   Cancer Prevention Research

Terpenoids from Zingiber officinale (Ginger) Induce Apoptosis in Endometrial Cancer Cells through the Activation of p53

(2013) Yang Liu et al.   PLoS One

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The Cytotoxicity Mechanism of 6-Shogaol-Treated HeLa Human Cervical Cancer Cells Revealed by Label-Free Shotgun Proteomics and Bioinformatics Analysis

(2012) Qun Liu et al.   Evidence-based Complementary and Alternative Medicine

Expression and prognostic relevance of STAT3 and cyclin D1 in non-small cell lung cancer

(2012) Ting Ai et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS

Molecular mechanism inhibiting human hepatocarcinoma cell invasion by 6-shogaol and 6-gingerol

(2012) Chia-Jui Weng et al.   MOLECULAR NUTRITION & FOOD RESEARCH

6-Shogaol Induces Apoptosis in Human Hepatocellular Carcinoma Cells and Exhibits Anti-Tumor Activity In Vivo through Endoplasmic Reticulum Stress

(2012) Rong Hu et al.   PLoS One

Shogaols at proapoptotic concentrations induce G2/M arrest and aberrant mitotic cell death associated with tubulin aggregation

(2011) Fei-Fei Gan et al.   APOPTOSIS

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Synthesis of a New [6]-Gingerol Analogue and Its Protective Effect with Respect to the Development of Metabolic Syndrome in Mice Fed a High-Fat Diet

(2011) Mayumi Okamoto et al.   JOURNAL OF MEDICINAL CHEMISTRY

Sorafenib inhibits growth and metastasis of hepatocellular carcinoma by blocking STAT3

(2011) Fang-Ming Gu   WORLD JOURNAL OF GASTROENTEROLOGY

6-Shogaol, an active constituent of ginger, inhibits breast cancer cell invasion by reducing matrix metalloproteinase-9 expression via blockade of nuclear factor-κB activation

(2010) H Ling et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effect of [6]-Shogaol on Cytosolic Ca2+Levels and Proliferation in Human Oral Cancer Cells (OC2)

(2010) Chung-Yi Chen et al.   JOURNAL OF NATURAL PRODUCTS

Anti-invasion effects of 6-shogaol and 6-gingerol, two active components in ginger, on human hepatocarcinoma cells

(2010) Chia-Jui Weng et al.   MOLECULAR NUTRITION & FOOD RESEARCH

6-Shogaol is more effective than 6-gingerol and curcumin in inhibiting 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in mice

(2010) Hou Wu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Crystal Structure of Human AKT1 with an Allosteric Inhibitor Reveals a New Mode of Kinase Inhibition

(2010) Wen-I Wu et al.   PLoS One

[6]-Gingerol Suppresses Colon Cancer Growth by Targeting Leukotriene A4 Hydrolase

(2009) Chul-Ho Jeong et al.   CANCER RESEARCH

6-Shogaol, an Active Constituent of Dietary Ginger, Induces Autophagy by Inhibiting the AKT/mTOR Pathway in Human Non-Small Cell Lung Cancer A549 Cells

(2009) Jen-Yu Hung et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol

(2009) Swarnalatha Dugasani et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cytotoxic components from the dried rhizomes of Zingiber officinaleRoscoe

(2008) Ju Sin Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

6-Shogaol induces apoptosis in human colorectal carcinoma cellsviaROS production, caspase activation, and GADD 153 expression

(2008) Min-Hsiung Pan et al.   MOLECULAR NUTRITION & FOOD RESEARCH