The Potent Cdc7-Dbf4 (DDK) Kinase Inhibitor XL413 Has Limited Activity in Many Cancer Cell Lines and Discovery of Potential New DDK Inhibitor Scaffolds

Title
The Potent Cdc7-Dbf4 (DDK) Kinase Inhibitor XL413 Has Limited Activity in Many Cancer Cell Lines and Discovery of Potential New DDK Inhibitor Scaffolds
Authors
Keywords
Kinase inhibitors, Phosphorylation, Apoptosis, Breast cancer, In vitro kinase assay, Small molecules, Thermal stability, Cell growth
Journal
PLoS One
Volume 9, Issue 11, Pages e113300
Publisher
Public Library of Science (PLoS)
Online
2014-11-21
DOI
10.1371/journal.pone.0113300

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