Dbf4 and Cdc7 Proteins Promote DNA Replication through Interactions with Distinct Mcm2–7 Protein Subunits

Cdc7-Dbf4 Kinase Overexpression in Multiple Cancers and Tumor Cell Lines Is Correlated with p53 Inactivation

(2015) Dorine Bonte et al.   NEOPLASIA

Mcm2 phosphorylation and the response to replicative stress

(2012) Brent E Stead et al.   BMC GENETICS

Eukaryotic Origin-Dependent DNA Replication In Vitro Reveals Sequential Action of DDK and S-CDK Kinases

(2011) Ryan C. Heller et al.   CELL

Saccharomyces cerevisiaeDbf4 Has Unique Fold Necessary for Interaction with Rad53 Kinase

(2011) Lindsay A. Matthews et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of Mcm2 modulates Mcm2–7 activity and affects the cell’s response to DNA damage

(2011) Brent E. Stead et al.   NUCLEIC ACIDS RESEARCH

The Dbf4 motif C zinc finger promotes DNA replication and mediates resistance to genotoxic stress

(2010) Darryl R. Jones et al.   CELL CYCLE

Mec1 Is One of Multiple Kinases that Prime the Mcm2-7 Helicase for Phosphorylation by Cdc7

(2010) John C.W. Randell et al.   MOLECULAR CELL

The Dbf4–Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4

(2010) Yi-Jun Sheu et al.   NATURE

Minichromosome maintenance proteins 2, 3 and 7 in medulloblastoma: overexpression and involvement in regulation of cell migration and invasion

(2010) K-M Lau et al.   ONCOGENE

Incremental Genetic Perturbations to MCM2-7 Expression and Subcellular Distribution Reveal Exquisite Sensitivity of Mice to DNA Replication Stress

(2010) Chen-Hua Chuang et al.   PLoS Genetics

Concerted Loading of Mcm2–7 Double Hexamers around DNA during DNA Replication Origin Licensing

(2009) Dirk Remus et al.   CELL

Incorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation

(2009) L. I. Francis et al.   GENES & DEVELOPMENT

Budding Yeast Dbf4 Sequences Required for Cdc7 Kinase Activation and Identification of a Functional Relationship Between the Dbf4 and Rev1 BRCT Domains

(2009) Victoria Harkins et al.   GENETICS

Dbf4-Cdc7 Phosphorylation of Mcm2 Is Required for Cell Growth

(2009) Irina Bruck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATP Binding and Hydrolysis by Mcm2 Regulate DNA Binding by Mcm Complexes

(2009) Brent E. Stead et al.   JOURNAL OF MOLECULAR BIOLOGY

A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

(2009) C. Evrin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Dbf4/Drf1-Dependent Kinase Cdc7 in DNA-Damage Checkpoint Control

(2008) Toshiya Tsuji et al.   MOLECULAR CELL