Opposite Roles for p38MAPK-Driven Responses and Reactive Oxygen Species in the Persistence and Resolution of Radiation-Induced Genomic Instability

The challenges of using fluorescent probes to detect and quantify specific reactive oxygen species in living cells

(2013) Christine C. Winterbourn   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

New era of radiotherapy: An update in radiation-induced lung disease

(2013) M.F.K. Benveniste et al.   CLINICAL RADIOLOGY

Small Molecule Inhibition of p38 MAP Kinase Extends the Replicative Life Span of Human ATR-Seckel Syndrome Fibroblasts

(2013) Hannah S. E. Tivey et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

DNA damage associated with mitosis and cytokinesis failure

(2013) M T Hayashi et al.   ONCOGENE

How Safe Is Safe Enough? Radiation Risk for a Human Mission to Mars

(2013) Francis A. Cucinotta et al.   PLoS One

Activation of p38 MAP kinase and stress signalling in fibroblasts from the progeroid Rothmund–Thomson syndrome

(2012) Terence Davis et al.   AGE

Persistence of Genetic Damage in Lymphocytes from Former Uranium Miners

(2012) F. Zölzer et al.   CYTOGENETIC AND GENOME RESEARCH

Accumulation of DNA damage in complex normal tissues after protracted low-dose radiation

(2012) Stefanie Schanz et al.   DNA REPAIR

Oxidative stress induces an ATM-independent senescence pathway through p38 MAPK-mediated lamin B1 accumulation

(2012) Aurelia Barascu et al.   EMBO JOURNAL

Radiation Carcinogenesis Risk Assessments for Never-smokers

(2012) Francis A. Cucinotta et al.   HEALTH PHYSICS

Yap1: A DNA damage responder in Saccharomyces cerevisiae

(2012) Lori A. Rowe et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Non-targeted effects of ionising radiation—Implications for low dose risk

(2012) Munira Kadhim et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

DNA breaks and chromosome pulverization from errors in mitosis

(2012) Karen Crasta et al.   NATURE

Exposure to Heavy Ion Radiation Induces Persistent Oxidative Stress in Mouse Intestine

(2012) Kamal Datta et al.   PLoS One

γH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization

(2011) Markus Löbrich et al.   CELL CYCLE

p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype

(2011) Adam Freund et al.   EMBO JOURNAL

The accumulation of un-repairable DNA damage in laminopathy progeria fibroblasts is caused by ROS generation and is prevented by treatment with N-acetyl cysteine

(2011) Shane A. Richards et al.   HUMAN MOLECULAR GENETICS

Persistence of γ-H2AX and 53BP1 foci in proliferating and non-proliferating human mammary epithelial cells after exposure to γ-rays or iron ions

(2011) Torsten Groesser et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Four faces of cellular senescence

(2011) Francis Rodier et al.   JOURNAL OF CELL BIOLOGY

Evidence for formation of DNA repair centers and dose-response nonlinearity in human cells

(2011) T. Neumaier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromosome Segregation Errors as a Cause of DNA Damage and Structural Chromosome Aberrations

(2011) A. Janssen et al.   SCIENCE

Feedback between p21 and reactive oxygen production is necessary for cell senescence

(2010) João F Passos et al.   Molecular Systems Biology

Micronuclei frequency in peripheral blood lymphocytes and cancer risk: evidence from human studies

(2010) S. Bonassi et al.   MUTAGENESIS

Radiation-induced premature senescence is associated with specific cytogenetic changes

(2010) Sebastian Zahnreich et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Higher-order chromatin structure in DSB induction, repair and misrepair

(2010) Martin Falk et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization

(2010) S.V. Costes et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Gene amplification, radiation sensitivity and DNA double-strand breaks

(2010) Chiara Mondello et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Genomic instability — an evolving hallmark of cancer

(2010) Simona Negrini et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Replication stress and oxidative damage contribute to aberrant constitutive activation of DNA damage signalling in human gliomas

(2010) J Bartkova et al.   ONCOGENE

Inducible response required for repair of low-dose radiation damage in human fibroblasts

(2010) S. Grudzenski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Participation of DNA-PKcs in DSB Repair after Exposure to High- and Low-LET Radiation

(2010) Jennifer A. Anderson et al.   RADIATION RESEARCH

Lung Cancer in Never Smokers: Clinical Epidemiology and Environmental Risk Factors

(2009) J. M. Samet et al.   CLINICAL CANCER RESEARCH

Healing and Hurting: Molecular Mechanisms, Functions, and Pathologies of Cellular Senescence

(2009) Peter D. Adams   MOLECULAR CELL

Long-term persistence of X-ray-induced genomic instability in quiescent normal human diploid cells

(2009) Keiji Suzuki et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

Chronic Oxidative Stress as a Mechanism for Radiation Nephropathy

(2009) Marek Lenarczyk et al.   RADIATION RESEARCH

Late Residual γ-H2AX Foci In Murine Skin are Dose Responsive and Predict RadiosensitivityIn Vivo

(2009) Nirmal Bhogal et al.   RADIATION RESEARCH

Hydrogen peroxide mediates the radiation-induced mutator phenotype in mammalian cells

(2008) Disha Dayal et al.   BIOCHEMICAL JOURNAL

DNA damage-induced reactive oxygen species (ROS) stress response in Saccharomyces cerevisiae

(2008) Lori A. Rowe et al.   FREE RADICAL BIOLOGY AND MEDICINE

 -H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin

(2008) A. Kinner et al.   NUCLEIC ACIDS RESEARCH

Repair of HZE-Particle-Induced DNA Double-Strand Breaks in Normal Human Fibroblasts

(2008) Aroumougame Asaithamby et al.   RADIATION RESEARCH

Activation of the Cellular DNA Damage Response in the Absence of DNA Lesions

(2008) E. Soutoglou et al.   SCIENCE