Activation of p38 MAP kinase and stress signalling in fibroblasts from the progeroid Rothmund–Thomson syndrome

The N-terminal region of RECQL4 lacking the helicase domain is both essential and sufficient for the viability of vertebrate cells

(2011) Takuya Abe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype

(2011) Adam Freund et al.   EMBO JOURNAL

RECQL4, the Protein Mutated in Rothmund-Thomson Syndrome, Functions in Telomere Maintenance

(2011) Avik K. Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rothmund-Thomson syndrome in siblings: evidence for acquired in vivo mosaicism

(2010) Noralane M. Lindor et al.   CLINICAL GENETICS

Rothmund–Thomson syndrome helicase, RECQ4: On the crossroad between DNA replication and repair

(2010) Yilun Liu   DNA REPAIR

Rothmund-Thomson syndrome

(2010) Lidia Larizza et al.   Orphanet Journal of Rare Diseases

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

(2009) Xiaohua Xu et al.   EMBO JOURNAL

Dual DNA unwinding activities of the Rothmund–Thomson syndrome protein, RECQ4

(2009) Xiaohua Xu et al.   EMBO JOURNAL

Can we intervene in human ageing?

(2009) Richard G.A. Faragher et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Assessing the role of stress signalling via p38 MAP kinase in the premature senescence of Ataxia Telangiectasia and Werner syndrome fibroblasts

(2008) Terence Davis et al.   BIOGERONTOLOGY

Sensitivity of RECQL4-deficient fibroblasts from Rothmund–Thomson syndrome patients to genotoxic agents

(2008) Weidong Jin et al.   HUMAN GENETICS

Homologous recombination and maintenance of genome integrity: Cancer and aging through the prism of human RecQ helicases

(2008) Karen J. Ouyang et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Identification of new RECQL4 mutations in Caucasian Rothmund–Thomson patients and analysis of sensitivity to a wide range of genotoxic agents

(2008) Rosa Estela Caseira Cabral et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS