Response to rituximab in patients with rheumatoid arthritis in different compartments of the immune system

B cell activation biomarkers as predictive factors for the response to rituximab in rheumatoid arthritis: A six-month, national, multicenter, open-label study

(2011) Jérémie Sellam et al.   ARTHRITIS AND RHEUMATISM

Decrease in immunoglobulin free light chains in patients with rheumatoid arthritis upon rituximab (anti-CD20) treatment correlates with decrease in disease activity

(2010) T. G. Kormelink et al.   ANNALS OF THE RHEUMATIC DISEASES

Inhibition of joint damage and improved clinical outcomes with rituximab plus methotrexate in early active rheumatoid arthritis: the IMAGE trial

(2010) P. P. Tak et al.   ANNALS OF THE RHEUMATIC DISEASES

Different stages of rheumatoid arthritis: features of the synovium in the preclinical phase

(2010) M. G. H. van de Sande et al.   ANNALS OF THE RHEUMATIC DISEASES

Relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis patients

(2010) Rogier M. Thurlings et al.   ARTHRITIS AND RHEUMATISM

Anti-citrullinated protein antibodies bind surface-expressed citrullinated Grp78 on monocyte/macrophages and stimulate tumor necrosis factor α production

(2010) Ming-Chi Lu et al.   ARTHRITIS AND RHEUMATISM

Management of nonresponse to rituximab in rheumatoid arthritis: Predictors and outcome of re-treatment

(2010) E. M. Vital et al.   ARTHRITIS AND RHEUMATISM

Steady-state generation of mucosal IgA+ plasmablasts is not abrogated by B-cell depletion therapy with rituximab

(2010) H. E. Mei et al.   BLOOD

Targeting B cells in immune-mediated inflammatory disease: A comprehensive review of mechanisms of action and identification of biomarkers

(2010) Thomas Dörner et al.   PHARMACOLOGY & THERAPEUTICS

B cells from rheumatoid arthritis patients show important alterations on the expression of CD86 and FcgammaRIIb, which are modulated by anti-tumor necrosis factor therapy

(2010) Diego Catalan et al.   ARTHRITIS RESEARCH & THERAPY

Regulatory B Cells in Autoimmune Diseases

(2009) Sébastien Lemoine et al.   Annals of the New York Academy of Sciences

Clinical response, pharmacokinetics, development of human anti-chimaeric antibodies, and synovial tissue response to rituximab treatment in patients with rheumatoid arthritis

(2009) R M Thurlings et al.   ANNALS OF THE RHEUMATIC DISEASES

The dynamics of macrophage lineage populations in inflammatory and autoimmune diseases

(2009) John A. Hamilton et al.   ARTHRITIS AND RHEUMATISM

Depletion of functionally active CD20+ T cells by rituximab treatment

(2009) Esther Wilk et al.   ARTHRITIS AND RHEUMATISM

CD20 deficiency in humans results in impaired T cell–independent antibody responses

(2009) Taco W. Kuijpers et al.   JOURNAL OF CLINICAL INVESTIGATION

Plasmacytoid Dendritic Cells Regulate Autoreactive B Cell Activation via Soluble Factors and in a Cell-to-Cell Contact Manner

(2009) C. Ding et al.   JOURNAL OF IMMUNOLOGY

Synovial Tissue Sublining CD68 Expression Is a Biomarker of Therapeutic Response in Rheumatoid Arthritis Clinical Trials: Consistency Across Centers

(2009) B. BRESNIHAN et al.   JOURNAL OF RHEUMATOLOGY

Molecular mechanisms of resistance to Rituximab and pharmacologic strategies for its circumvention

(2009) Claudia Stolz et al.   LEUKEMIA & LYMPHOMA

Class-switched B cells display response to therapeutic B cell depletion in rheumatoid arthritis

(2009) Burkhard Moller et al.   ARTHRITIS RESEARCH & THERAPY

Short- and long-term effects of anti-CD20 treatment on B cell ontogeny in bone marrow of patients with rheumatoid arthritis

(2009) Maria Rehnberg et al.   ARTHRITIS RESEARCH & THERAPY

Rituximab therapy reduces activated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: depletion of memory B cells correlates with clinical response

(2009) Magda Nakou et al.   ARTHRITIS RESEARCH & THERAPY

Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium

(2009) Frances Humby et al.   PLOS MEDICINE

Rituximab-Induced Changes in Hematolymphoid Tissues Found at Autopsy

(2008) Adina M. Cioc et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Residual inflammation after rituximab treatment is associated with sustained synovial plasma cell infiltration and enhanced B cell repopulation

(2008) Y K O Teng et al.   ANNALS OF THE RHEUMATIC DISEASES

Clinical significance of synovial lymphoid neogenesis and its reversal after anti-tumour necrosis factor   therapy in rheumatoid arthritis

(2008) J D Canete et al.   ANNALS OF THE RHEUMATIC DISEASES

Anti-CD20 therapy in patients with rheumatoid arthritis: Predictors of response and B cell subset regeneration after repeated treatment

(2008) Petra Roll et al.   ARTHRITIS AND RHEUMATISM

Synovial lymphoid neogenesis does not define a specific clinical rheumatoid arthritis phenotype

(2008) Rogier M. Thurlings et al.   ARTHRITIS AND RHEUMATISM

Highly sensitive B cell analysis predicts response to rituximab therapy in rheumatoid arthritis

(2008) Shouvik Dass et al.   ARTHRITIS AND RHEUMATISM

Induction of macrophage secretion of tumor necrosis factor α through Fcγ receptor IIa engagement by rheumatoid arthritis–specific autoantibodies to citrullinated proteins complexed with fibrinogen

(2008) Cyril Clavel et al.   ARTHRITIS AND RHEUMATISM

B lymphocytes: how they develop and function

(2008) T. W. LeBien et al.   BLOOD

Complement and cellular cytotoxicity in antibody therapy of cancer

(2008) Siao-Yi Wang et al.   EXPERT OPINION ON BIOLOGICAL THERAPY