Cucurbitacin E Induces Cell Cycle G2/M Phase Arrest and Apoptosis in Triple Negative Breast Cancer

Cucurbitacin E as Inducer of Cell Death and Apoptosis in Human Oral Squamous Cell Carcinoma Cell Line SAS

(2013) Chao-Ming Hung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Effectiveness of Cucurbitacin B in BRCA1 Defective Breast Cancer Cells

(2013) Moltira Promkan et al.   PLoS One

Biological activities and potential molecular targets of cucurbitacins

(2012) Xiuping Chen et al.   ANTI-CANCER DRUGS

Cucurbitacin E inhibits breast tumor metastasis by suppressing cell migration and invasion

(2012) Tao Zhang et al.   BREAST CANCER RESEARCH AND TREATMENT

Cucurbitacin E Induces G2/M Phase Arrest through STAT3/p53/p21 Signaling and Provokes ApoptosisviaFas/CD95 and Mitochondria-Dependent Pathways in Human Bladder Cancer T24 Cells

(2012) Wen-Wen Huang et al.   Evidence-based Complementary and Alternative Medicine

Cucurbitacin B Induces Cell Cycle Arrest, Apoptosis and Autophagy Associated with G Actin Reduction and Persistent Activation of Cofilin in Jurkat Cells

(2012) Jun-Shan Zhu et al.   PHARMACOLOGY

Inhibitory effect of cucurbitacin E on the proliferation of ovarian cancer cells and its mechanism

(2012) Xiao-Lei Shan et al.   Chinese Journal of Cancer

Cucurbitacin-I (JSI-124) activates the JNK/c-Jun signaling pathway independent of apoptosis and cell cycle arrest in B Leukemic Cells

(2011) Ganchimeg Ishdorj et al.   BMC CANCER

Cucurbitacin B inhibits 12-O-tetradecanoylphorbol 13-acetate-induced invasion and migration of human hepatoma cells through inactivating mitogen-activated protein kinase and PI3K/Akt signal transduction pathways

(2011) Xueying Zhou et al.   HEPATOLOGY RESEARCH

The induction of G2/M cell-cycle arrest and apoptosis by cucurbitacin E is associated with increased phosphorylation of eIF2α in leukemia cells

(2010) Yanchun Li et al.   ANTI-CANCER DRUGS

Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway

(2010) Y. Dong et al.   CARCINOGENESIS

Triple-Negative Breast Cancer

(2010) William D. Foulkes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cucurbitacin B Induces Apoptosis by Inhibition of the JAK/STAT Pathway and Potentiates Antiproliferative Effects of Gemcitabine on Pancreatic Cancer Cells

(2009) N. H. Thoennissen et al.   CANCER RESEARCH

Cucurbitacin B induces G2arrest and apoptosisviaa reactive oxygen species-dependent mechanism in human colon adenocarcinoma SW480 cells

(2009) Shusuke Yasuda et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Cytotoxic Properties of Root Extract and Fruit Juice ofTrichosanthes cucumerina

(2009) Sumonthip Kongtun et al.   PLANTA MEDICA

Targeted constitutive activation of signal transducer and activator of transcription 3 in human hepatocellular carcinoma cells by cucurbitacin B

(2008) Meixia Zhang et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Cucurbitacin B has a potent antiproliferative effect on breast cancer cellsin vitroandin vivo

(2008) Naoki Wakimoto et al.   CANCER SCIENCE

Inhibitory effects of cucurbitacin B on laryngeal squamous cell carcinoma

(2008) Tingyan Liu et al.   EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

Cucurbitacin B markedly inhibits growth and rapidly affects the cytoskeleton in glioblastoma multiforme

(2008) Dong Yin et al.   INTERNATIONAL JOURNAL OF CANCER

EdU, a new thymidine analogue for labelling proliferating cells in the nervous system

(2008) Fatemah Chehrehasa et al.   JOURNAL OF NEUROSCIENCE METHODS

Octanorcucurbitane and Cucurbitane Triterpenoids from the Tubers ofHemsleya endecaphyllawith HIV-1 Inhibitory Activity

(2007) Jian-Chao Chen et al.   JOURNAL OF NATURAL PRODUCTS