Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway

Inhibitory effect of cucurbitacin E on the proliferation of ovarian cancer cells and its mechanism

(2012) Xiao-Lei Shan et al.   Chinese Journal of Cancer

Cucurbitacin E as a new inhibitor of cofilin phosphorylation in human leukemia U937 cells

(2010) Souichi Nakashima et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Activated STAT3 is a mediator and biomarker of VEGF endothelial activation

(2010) Shao-Hua Chen et al.   CANCER BIOLOGY & THERAPY

Cucurbitacin B, a small molecule inhibitor of the Stat3 signaling pathway, enhances the chemosensitivity of laryngeal squamous cell carcinoma cells to cisplatin

(2010) Tingyan Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Preclinical pharmacokinetics and in vitro metabolism of brivanib (BMS-540215), a potent VEGFR2 inhibitor and its alanine ester prodrug brivanib alaninate

(2009) Punit H. Marathe et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Cucurbitacin B Induces Apoptosis by Inhibition of the JAK/STAT Pathway and Potentiates Antiproliferative Effects of Gemcitabine on Pancreatic Cancer Cells

(2009) N. H. Thoennissen et al.   CANCER RESEARCH

Inhibitory effect of cucurbitacin E on pancreatic cancer cells growth via STAT3 signaling

(2009) Chunyan Sun et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Gambogic Acid Inhibits Angiogenesis and Prostate Tumor Growth by Suppressing Vascular Endothelial Growth Factor Receptor 2 Signaling

(2008) T. Yi et al.   CANCER RESEARCH

A novel peptide from human apolipoprotein(a) inhibits angiogenesis and tumor growth by targeting c-Src phosphorylation in VEGF-induced human umbilical endothelial cells

(2008) Zheng-Fang Yi et al.   INTERNATIONAL JOURNAL OF CANCER

AIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in mice

(2008) Haifeng Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

An Autocrine VEGF/VEGFR2 and p38 Signaling Loop Confers Resistance to 4-Hydroxytamoxifen in MCF-7 Breast Cancer Cells

(2008) R. Aesoy et al.   MOLECULAR CANCER RESEARCH

Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways

(2008) T. Yi et al.   MOLECULAR CANCER THERAPEUTICS

Screening of biochemical modulator by tumor cell permeability of doxorubicin

(2007) Yasuyuki Sadzuka et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

STAT3: A critical transcription activator in angiogenesis

(2007) Zhong Chen et al.   MEDICINAL RESEARCH REVIEWS