Cucurbitacin-I (JSI-124) activates the JNK/c-Jun signaling pathway independent of apoptosis and cell cycle arrest in B Leukemic Cells

Cucurbitacin: Ancient Compound Shedding New Light on Cancer Treatment

(2011) Dhong Hyun Lee et al.   TheScientificWorldJOURNAL

JSI-124 inhibits glioblastoma multiforme cell proliferation through G2/M cell cycle arrest and apoptosis augmentation

(2010) Yuhang Su et al.   CANCER BIOLOGY & THERAPY

Lysophosphatidic acid receptor expression in chronic lymphocytic leukemia leads to cell survival mediated though vascular endothelial growth factor expression

(2010) Sekar Ashok Kumar et al.   LEUKEMIA & LYMPHOMA

Inhibition of Constitutive Activation of STAT3 by Curcurbitacin-I (JSI-124) Sensitized Human B-Leukemia Cells to Apoptosis

(2010) G. Ishdorj et al.   MOLECULAR CANCER THERAPEUTICS

The role of the c-Jun N-terminal kinase 2-α-isoform in non-small cell lung carcinoma tumorigenesis

(2010) R T Nitta et al.   ONCOGENE

Vascular endothelial growth factor-C (VEGF-C) promotes angiogenesis by induction of COX-2 in leukemic cells via the VEGF-R3/JNK/ AP-1 pathway

(2009) Ming-Hsien Chien et al.   CARCINOGENESIS

Genetic and pharmacological inhibition of JNK ameliorates hypoxia-induced retinopathy through interference with VEGF expression

(2009) M. Guma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lysophosphatidic acid (LPA) induces the expression of VEGF leading to protection against apoptosis in B-cell derived malignancies

(2008) Xiaojie Hu et al.   CELLULAR SIGNALLING

Synergistic antitumor effects of CpG oligodeoxynucleotide and STAT3 inhibitory agent JSI-124 in a mouse melanoma tumor model

(2008) Ommoleila Molavi et al.   IMMUNOLOGY AND CELL BIOLOGY

Lysophosphatidic Acid Protects Cancer Cells from Histone Deacetylase (HDAC) Inhibitor-induced Apoptosis through Activation of HDAC

(2008) Ganchimeg Ishdorj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY