Carbamazepine Potentiates the Effectiveness of Morphine in a Rodent Model of Neuropathic Pain

Identification of a functional interaction of HMGB1 with Receptor for Advanced Glycation End-products in a model of neuropathic pain

(2014) Yohance M. Allette et al.   BRAIN BEHAVIOR AND IMMUNITY

Voltage-Gated Sodium Channel Expression in Mouse DRG after SNI Leads to Re-Evaluation of Projections of Injured Fibers

(2014) Cédric J Laedermann et al.   Molecular Pain

Regulating excitability of peripheral afferents: emerging ion channel targets

(2014) Stephen G Waxman et al.   NATURE NEUROSCIENCE

Lipopolysaccharide differentially modulates expression of cytokines and cyclooxygenases in dorsal root ganglion cells via Toll-like receptor-4 dependent pathways

(2014) K.-H. Tse et al.   NEUROSCIENCE

Pain without Nociceptors? Nav1.7-Independent Pain Mechanisms

(2014) Michael S. Minett et al.   Cell Reports

Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain

(2013) Susannah S. Lewis et al.   BRAIN BEHAVIOR AND IMMUNITY

Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain

(2013) Cédric J. Laedermann et al.   JOURNAL OF CLINICAL INVESTIGATION

Toll-like receptor signaling adapter proteins govern spread of neuropathic pain and recovery following nerve injury in male mice

(2013) Jennifer A Stokes et al.   Journal of Neuroinflammation

Blockade of Toll-Like Receptor 4 Attenuates Morphine Tolerance and Facilitates the Pain Relieving Properties of Morphine

(2013) L. N. Eidson et al.   JOURNAL OF NEUROSCIENCE

The Efficacy of Morphine, Pregabalin, Gabapentin, and Duloxetine on Mechanical Allodynia Is Different from That on Neuroma Pain in the Rat Neuropathic Pain Model

(2012) Rika Miyazaki et al.   ANESTHESIA AND ANALGESIA

Rufinamide Attenuates Mechanical Allodynia in a Model of Neuropathic Pain in the Mouse and Stabilizes Voltage-gated Sodium Channel Inactivated State

(2012) Marc R. Suter et al.   ANESTHESIOLOGY

Gabapentin reduces allodynia and hyperalgesia in painful diabetic neuropathy rats by decreasing expression level of Nav1.7 and p-ERK1/2 in DRG neurons

(2012) Jun-Long Zhang et al.   BRAIN RESEARCH

Suppression of pain-related behavior in two distinct rodent models of peripheral neuropathy by a homopolyarginine-conjugated CRMP2 peptide

(2012) Weina Ju et al.   JOURNAL OF NEUROCHEMISTRY

The persistent release of HMGB1 contributes to tactile hyperalgesia in a rodent model of neuropathic pain

(2012) Polina Feldman et al.   Journal of Neuroinflammation

Sodium Channels and Mammalian Sensory Mechanotransduction

(2012) Ramin Raouf et al.   Molecular Pain

The NaV1.7 sodium channel: from molecule to man

(2012) Sulayman D. Dib-Hajj et al.   NATURE REVIEWS NEUROSCIENCE

Morphine activates neuroinflammation in a manner parallel to endotoxin

(2012) X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Merging Structural Motifs of Functionalized Amino Acids and α-Aminoamides Results in Novel Anticonvulsant Compounds with Significant Effects on Slow and Fast Inactivation of Voltage-Gated Sodium Channels and in the Treatment of Neuropathic Pain

(2011) Yuying Wang et al.   ACS Chemical Neuroscience

LPS Sensitizes TRPV1 via Activation of TLR4 in Trigeminal Sensory Neurons

(2011) A. Diogenes et al.   JOURNAL OF DENTAL RESEARCH

Distinct Mechanisms Underlying Pronociceptive Effects of Opioids

(2011) C. Heinl et al.   JOURNAL OF NEUROSCIENCE

Spinal Cord Toll-Like Receptor 4 Mediates Inflammatory and Neuropathic Hypersensitivity in Male But Not Female Mice

(2011) R. E. Sorge et al.   JOURNAL OF NEUROSCIENCE

Inhibition of Nav 4 Peptide-Mediated Resurgent Sodium Currents in Nav1.7 Channels by Carbamazepine, Riluzole, and Anandamide

(2011) J. W. Theile et al.   MOLECULAR PHARMACOLOGY

Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca2+ channel complex

(2011) Joel M Brittain et al.   NATURE MEDICINE

Exploring the Neuroimmunopharmacology of Opioids: An Integrative Review of Mechanisms of Central Immune Signaling and Their Implications for Opioid Analgesia

(2011) M. R. Hutchinson et al.   PHARMACOLOGICAL REVIEWS

Bacterial cell products signal to mouse colonic nociceptive dorsal root ganglia neurons

(2010) Fernando Ochoa-Cortes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Pivotal Role of TLR4 Receptors in Alcohol-Induced Neuroinflammation and Brain Damage

(2010) S. Alfonso-Loeches et al.   JOURNAL OF NEUROSCIENCE

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

(2010) Mattia Maroso et al.   NATURE MEDICINE

Treatment of Neuropathic Pain: An Overview of Recent Guidelines

(2009) Alec B. O'Connor et al.   AMERICAN JOURNAL OF MEDICINE

A novel Nav1.7 mutation producing carbamazepine-responsive erythromelalgia

(2009) Tanya Z. Fischer et al.   ANNALS OF NEUROLOGY

Evidence that opioids may have toll-like receptor 4 and MD-2 effects

(2009) Mark R. Hutchinson et al.   BRAIN BEHAVIOR AND IMMUNITY

Sodium channel activity modulates multiple functions in microglia

(2009) Joel A. Black et al.   GLIA

Induction of Synaptic Long-Term Potentiation After Opioid Withdrawal

(2009) R. Drdla et al.   SCIENCE

Differential Block of Sensory Neuronal Voltage-Gated Sodium Channels by Lacosamide [(2R)-2-(Acetylamino)-N-benzyl-3-methoxypropanamide], Lidocaine, and Carbamazepine

(2008) P. L. Sheets et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS