- Home
- Publications
- Publication Search
- Publication Details
Title
The NaV1.7 sodium channel: from molecule to man
Authors
Keywords
-
Journal
NATURE REVIEWS NEUROSCIENCE
Volume 14, Issue 1, Pages 49-62
Publisher
Springer Nature
Online
2012-12-12
DOI
10.1038/nrn3404
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Functional profiles of SCN9A variants in dorsal root ganglion neurons and superior cervical ganglion neurons correlate with autonomic symptoms in small fibre neuropathy
- (2012) Chongyang Han et al. BRAIN
- Membrane properties and electrogenesis in the distal axons of small dorsal root ganglion neurons in vitro
- (2012) Dmytro V. Vasylyev et al. JOURNAL OF NEUROPHYSIOLOGY
- Sodium Channel Nav1.7 Is Essential for Lowering Heat Pain Threshold after Burn Injury
- (2012) S. D. Shields et al. JOURNAL OF NEUROSCIENCE
- Reduction of Voltage Gated Sodium Channel Protein in DRG by Vector Mediated miRNA Reduces Pain in Rats with Painful Diabetic Neuropathy
- (2012) Munmun Chattopadhyay et al. Molecular Pain
- Expression of Nav1.7 in DRG Neurons Extends from Peripheral Terminals in the Skin to Central Preterminal Branches and Terminals in the Dorsal Horn
- (2012) Joel A Black et al. Molecular Pain
- Nav1.7-related small fiber neuropathy: Impaired slow-inactivation and DRG neuron hyperexcitability
- (2012) C. Han et al. NEUROLOGY
- Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons
- (2012) Michael S. Minett et al. Nature Communications
- Structural modelling and mutant cycle analysis predict pharmacoresponsiveness of a Nav1.7 mutant channel
- (2012) Yang Yang et al. Nature Communications
- Gene therapy for pain: Results of a phase I clinical trial
- (2011) David J. Fink et al. ANNALS OF NEUROLOGY
- Gain of function NaV1.7 mutations in idiopathic small fiber neuropathy
- (2011) Catharina G. Faber et al. ANNALS OF NEUROLOGY
- NaChBac: The Long Lost Sodium Channel Ancestor
- (2011) Kalypso Charalambous et al. BIOCHEMISTRY
- Discovery of XEN907, a spirooxindole blocker of NaV1.7 for the treatment of pain
- (2011) Sultan Chowdhury et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Deletion mutation of sodium channel NaV1.7 in inherited erythromelalgia: enhanced slow inactivation modulates dorsal root ganglion neuron hyperexcitability
- (2011) X. Cheng et al. BRAIN
- Vector-mediated release of GABA attenuates pain-related behaviors and reduces NaV1.7 in DRG neurons
- (2011) Munmun Chattopadhyay et al. EUROPEAN JOURNAL OF PAIN
- NaV1.7 accumulates and co-localizes with phosphorylated ERK1/2 within transected axons in early experimental neuromas
- (2011) Anna-Karin Persson et al. EXPERIMENTAL NEUROLOGY
- Voltage-Gated Sodium Channel Nav1.7 Maintains the Membrane Potential and Regulates the Activation and Chemokine-Induced Migration of a Monocyte-Derived Dendritic Cell Subset
- (2011) K. Kis-Toth et al. JOURNAL OF IMMUNOLOGY
- Identification of a Potent, State-Dependent Inhibitor of Nav1.7 with Oral Efficacy in the Formalin Model of Persistent Pain
- (2011) Howard Bregman et al. JOURNAL OF MEDICINAL CHEMISTRY
- Physiological interactions between Nav1.7 and Nav1.8 sodium channels: a computer simulation study
- (2011) Jin-Sung Choi et al. JOURNAL OF NEUROPHYSIOLOGY
- Nav1.7 is the Predominant Sodium Channel in Rodent Olfactory Sensory Neurons
- (2011) Hye-Sook Ahn et al. Molecular Pain
- Intra- and Interfamily Phenotypic Diversity in Pain Syndromes Associated with a Gain-of-Function Variant of NaV1.7
- (2011) Mark Estación et al. Molecular Pain
- Interactions of Key Charged Residues Contributing to Selective Block of Neuronal Sodium Channels by -Conotoxin KIIIA
- (2011) J. R. McArthur et al. MOLECULAR PHARMACOLOGY
- Loss-of-function mutations in sodium channel Nav1.7 cause anosmia
- (2011) Jan Weiss et al. NATURE
- The crystal structure of a voltage-gated sodium channel
- (2011) Jian Payandeh et al. NATURE
- -Conotoxins that differentially block sodium channels NaV1.1 through 1.8 identify those responsible for action potentials in sciatic nerve
- (2011) M. J. Wilson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Molecular Basis of Acid Insensitivity in the African Naked Mole-Rat
- (2011) E. S. J. Smith et al. SCIENCE
- Sodium Channels in Normal and Pathological Pain
- (2010) Sulayman D. Dib-Hajj et al. Annual Review of Neuroscience
- Alternative splicing may contribute to time-dependent manifestation of inherited erythromelalgia
- (2010) Jin-Sung Choi et al. BRAIN
- Targeting Primary Afferent Nerves for Novel Antitussive Therapy
- (2010) Bradley J. Undem et al. CHEST
- A Nonsense Mutation in the SCN9A Gene in Congenital Insensitivity to Pain
- (2010) Mazen Kurban et al. DERMATOLOGY
- Two novel mutations of SCN9A (Nav1.7) are associated with partial congenital insensitivity to pain
- (2010) Roland Staudl et al. EUROPEAN JOURNAL OF PAIN
- Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents
- (2010) Brian W. Jarecki et al. JOURNAL OF CLINICAL INVESTIGATION
- ERK1/2 Mitogen-Activated Protein Kinase Phosphorylates Sodium Channel Nav1.7 and Alters Its Gating Properties
- (2010) S. Stamboulian et al. JOURNAL OF NEUROSCIENCE
- Recommendations for the Pharmacological Management of Neuropathic Pain: An Overview and Literature Update
- (2010) Robert H. Dworkin et al. MAYO CLINIC PROCEEDINGS
- Mutations at opposite Ends of the DIII/S4-S5 Linker of Sodium Channel NaV1.7 Produce Distinct Pain Disorders
- (2010) Xiaoyang Cheng et al. Molecular Pain
- Paroxysmal extreme pain disorder: a molecular lesion of peripheral neurons
- (2010) Jin-Sung Choi et al. Nature Reviews Neurology
- Electrophysiology and beyond: Multiple roles of Na+ channel β subunits in development and disease
- (2010) Gustavo A. Patino et al. NEUROSCIENCE LETTERS
- Isoform-specific and pan-channel partners regulate trafficking and plasma membrane stability; and alter sodium channel gating properties
- (2010) Sulayman D. Dib-Hajj et al. NEUROSCIENCE LETTERS
- Signaling complexes of voltage-gated sodium and calcium channels
- (2010) William A. Catterall NEUROSCIENCE LETTERS
- Voltage-gated sodium channel organization in neurons: Protein interactions and trafficking pathways
- (2010) Christophe Leterrier et al. NEUROSCIENCE LETTERS
- Pain perception is altered by a nucleotide polymorphism in SCN9A
- (2010) F. Reimann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cyclization of conotoxins to improve their biopharmaceutical properties
- (2010) Richard J. Clark et al. TOXICON
- A sodium channel geneSCN9Apolymorphism that increases nociceptor excitability
- (2009) Mark Estacion et al. ANNALS OF NEUROLOGY
- A novel Nav1.7 mutation producing carbamazepine-responsive erythromelalgia
- (2009) Tanya Z. Fischer et al. ANNALS OF NEUROLOGY
- Early- and late-onset inherited erythromelalgia: genotype–phenotype correlation
- (2009) Chongyang Han et al. BRAIN
- Subtype-selective targeting of voltage-gated sodium channels
- (2009) Steve England et al. BRITISH JOURNAL OF PHARMACOLOGY
- Mexiletine-responsive erythromelalgia due to a new Nav1.7 mutation showing use-dependent current fall-off
- (2009) Jin-Sung Choi et al. EXPERIMENTAL NEUROLOGY
- Transfection of rat or mouse neurons by biolistics or electroporation
- (2009) Sulayman D Dib-Hajj et al. Nature Protocols
- Two novel SCN9A mutations causing insensitivity to pain
- (2009) K. B. Nilsen et al. PAIN
- A Role of SCN9A in Human Epilepsies, As a Cause of Febrile Seizures and As a Potential Modifier of Dravet Syndrome
- (2009) Nanda A. Singh et al. PLoS Genetics
- Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas
- (2008) Joel A. Black et al. ANNALS OF NEUROLOGY
- Imidazopyridines: A novel class of hNav1.7 channel blockers
- (2008) Clare London et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Voltage-gated sodium channels in pain states: Role in pathophysiology and targets for treatment
- (2008) Sulayman D. Dib-Hajj et al. BRAIN RESEARCH REVIEWS
- A Pore-blocking Hydrophobic Motif at the Cytoplasmic Aperture of the Closed-state Nav1.7 Channel Is Disrupted by the Erythromelalgia-associated F1449V Mutation
- (2008) Angelika Lampert et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tarantula Huwentoxin-IV Inhibits Neuronal Sodium Channels by Binding to Receptor Site 4 and Trapping the Domain II Voltage Sensor in the Closed Configuration
- (2008) Yucheng Xiao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NaV1.7 Gain-of-Function Mutations as a Continuum: A1632E Displays Physiological Changes Associated with Erythromelalgia and Paroxysmal Extreme Pain Disorder Mutations and Produces Symptoms of Both Disorders
- (2008) M. Estacion et al. JOURNAL OF NEUROSCIENCE
- Continuous -Opioid Receptor Activation Reduces Neuronal Voltage-Gated Sodium Channel (NaV1.7) Levels through Activation of Protein Kinase C in Painful Diabetic Neuropathy
- (2008) M. Chattopadhyay et al. JOURNAL OF NEUROSCIENCE
- Differential Block of Sensory Neuronal Voltage-Gated Sodium Channels by Lacosamide [(2R)-2-(Acetylamino)-N-benzyl-3-methoxypropanamide], Lidocaine, and Carbamazepine
- (2008) P. L. Sheets et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Voltage-gated sodium channels in nociceptiveversusnon-nociceptive nodose vagal sensory neurons innervating guinea pig lungs
- (2008) Kevin Kwong et al. JOURNAL OF PHYSIOLOGY-LONDON
- Paroxysmal Extreme Pain Disorder M1627K Mutation in Human Nav1.7 Renders DRG Neurons Hyperexcitable
- (2008) Sulayman D Dib-Hajj et al. Molecular Pain
- Mutation I136V Alters Electrophysiological Properties of the NaV1.7 Channel in a Family with Onset of Erythromelalgia in the Second Decade
- (2008) Xiaoyang Cheng et al. Molecular Pain
- Sensory and motor complications of local anesthetics
- (2008) Peter Gerner et al. MUSCLE & NERVE
- Selective Inflammatory Pain Insensitivity in the African Naked Mole-Rat (Heterocephalus glaber)
- (2008) Thomas J Park et al. PLOS BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More