The persistent release of HMGB1 contributes to tactile hyperalgesia in a rodent model of neuropathic pain

HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4

(2012) Milena Schiraldi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Graphene Arrested in Laponite–Water Colloidal Glass

(2012) Saeed M. Alhassan et al.   LANGMUIR

Glycyrrhizic acid affords robust neuroprotection in the postischemic brain via anti-inflammatory effect by inhibiting HMGB1 phosphorylation and secretion

(2012) Seung-Woo Kim et al.   NEUROBIOLOGY OF DISEASE

Merging Structural Motifs of Functionalized Amino Acids and α-Aminoamides Results in Novel Anticonvulsant Compounds with Significant Effects on Slow and Fast Inactivation of Voltage-Gated Sodium Channels and in the Treatment of Neuropathic Pain

(2011) Yuying Wang et al.   ACS Chemical Neuroscience

IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizures

(2011) Annamaria Vezzani et al.   BRAIN BEHAVIOR AND IMMUNITY

Effects of intrathecal epigallocatechin gallate, an inhibitor of Toll-like receptor 4, on chronic neuropathic pain in rats

(2011) Xin Kuang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

LPS Sensitizes TRPV1 via Activation of TLR4 in Trigeminal Sensory Neurons

(2011) A. Diogenes et al.   JOURNAL OF DENTAL RESEARCH

HMGB1 inhibitor glycyrrhizin attenuates intracerebral hemorrhage-induced injury in rats

(2011) Masatoshi Ohnishi et al.   NEUROPHARMACOLOGY

Anti-HMGB1 Neutralization Antibody Improves Pain-Related Behavior Induced by Application of Autologous Nucleus Pulposus Onto Nerve Roots in Rats

(2011) Ken-ichi Otoshi et al.   SPINE

Bacterial cell products signal to mouse colonic nociceptive dorsal root ganglia neurons

(2010) Fernando Ochoa-Cortes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Redox remodeling: a candidate regulator of HMGB1 function in injured skeletal muscle

(2010) Michela Vezzoli et al.   Annals of the New York Academy of Sciences

Spinal high-mobility group box 1 contributes to mechanical allodynia in a rat model of bone cancer pain

(2010) Wei Tong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of HMGB1 in the pathogenesis of rheumatic disease

(2010) Ulf Andersson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Analysis of Nuclear High Mobility Group Box 1 (HMGB1)-Binding Proteins in Colon Cancer Cells: Clustering with Proteins Involved in Secretion and Extranuclear Function

(2010) Hanna Lee et al.   JOURNAL OF PROTEOME RESEARCH

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

(2010) Mattia Maroso et al.   NATURE MEDICINE

Induction of high mobility group box-1 in dorsal root ganglion contributes to pain hypersensitivity after peripheral nerve injury

(2010) Masayuki Shibasaki et al.   PAIN

Differential ATF3 expression in dorsal root ganglion neurons reveals the profile of primary afferents engaged by diverse noxious chemical stimuli

(2010) João M. Bráz et al.   PAIN

A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

(2010) H. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of occupational activity with radiographic knee osteoarthritis and lumbar spondylosis in elderly patients of population-based cohorts: A large-scale population-based study

(2009) Shigeyuki Muraki et al.   ARTHRITIS AND RHEUMATISM

Protection by Glycyrrhizin against Warm Ischemia-Reperfusion–Induced Cellular Injury and Derangement of the Microcirculatory Blood Flow in the Rat Liver

(2009) Ayako Mabuchi et al.   MICROCIRCULATION

Postnatal Inflammation Increases Seizure Susceptibility in Adult Rats

(2008) M. A. Galic et al.   JOURNAL OF NEUROSCIENCE

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(2008) John Klune et al.   MOLECULAR MEDICINE