Anti-TNF Treatment Response in Rheumatoid Arthritis Patients Is Associated with Genetic Variation in the NLRP3-Inflammasome

High-Quality and -Quantity DNA Extraction from Frozen Archival Blood Clots for Genotyping of Single-Nucleotide Polymorphisms

(2013) Steffen Bank et al.   Genetic Testing and Molecular Biomarkers

S100A8 and S100A9 Induce Cytokine Expression and Regulate the NLRP3 Inflammasome via ROS-Dependent Activation of NF-κB1

(2013) Jean-Christophe Simard et al.   PLoS One

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis

(2012) Sophine B. Krintel et al.   Pharmacogenetics and Genomics

Validation Study of Existing Gene Expression Signatures for Anti-TNF Treatment in Patients with Rheumatoid Arthritis

(2012) Erik J. M. Toonen et al.   PLoS One

Common Genetic Variations in the NALP3 Inflammasome Are Associated with Delayed Apoptosis of Human Neutrophils

(2012) Robert Blomgran et al.   PLoS One

Optimising treatment in rheumatoid arthritis: a review of potential biological markers of response

(2011) P. Emery et al.   ANNALS OF THE RHEUMATIC DISEASES

Recommendations for publication of genetic association studies inArthritis & Rheumatism

(2011) Robert M. Plenge et al.   ARTHRITIS AND RHEUMATISM

Replication of association of the PTPRC gene with response to anti-tumor necrosis factor therapy in a large UK cohort

(2011) Darren Plant et al.   ARTHRITIS AND RHEUMATISM

Anti-TNF therapy: Safety aspects of taking the risk

(2011) Hemda Rosenblum et al.   AUTOIMMUNITY REVIEWS

A regulatory polymorphism in promoter region of TNFR1 gene is associated with Kawasaki disease in Chinese individuals

(2011) Guo-Bing Wang et al.   HUMAN IMMUNOLOGY

A Genetic Variant in the IL-17 Promoter Is Functionally Associated with Acute Graft-Versus-Host Disease after Unrelated Bone Marrow Transplantation

(2011) J. Luis Espinoza et al.   PLoS One

Intrinsic danger: activation of Toll-like receptors in rheumatoid arthritis

(2011) F. G. Goh et al.   RHEUMATOLOGY

Negative regulation of NF-κB and its involvement in rheumatoid arthritis

(2011) Geert van Loo et al.   ARTHRITIS RESEARCH & THERAPY

Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF B signalling pathways

(2010) C. Potter et al.   ANNALS OF THE RHEUMATIC DISEASES

Genetic Variants in Toll-Like Receptors Are Not Associated with Rheumatoid Arthritis Susceptibility or Anti-Tumour Necrosis Factor Treatment Outcome

(2010) Marieke J. H. Coenen et al.   PLoS One

DANBIO--powerful research database and electronic patient record

(2010) M. L. Hetland   RHEUMATOLOGY

Direct comparison of treatment responses, remission rates, and drug adherence in patients with rheumatoid arthritis treated with adalimumab, etanercept, or infliximab: Results from eight years of surveillance of clinical practice in the nationwide Danish DANBIO registry

(2009) Merete Lund Hetland et al.   ARTHRITIS AND RHEUMATISM

Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma

(2009) Yuki Hitomi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Rheumatoid arthritis

(2009) Lars Klareskog et al.   LANCET

Tobacco Smoke: Involvement of Reactive Oxygen Species and Stable Free Radicals in Mechanisms of Oxidative Damage, Carcinogenesis and Synergistic Effects with Other Respirable Particles

(2009) Athanasios Valavanidis et al.   International Journal of Environmental Research and Public Health

Do changes in prescription practice in patients with rheumatoid arthritis treated with biological agents affect treatment response and adherence to therapy? Results from the nationwide Danish DANBIO Registry

(2008) M L Hetland et al.   ANNALS OF THE RHEUMATIC DISEASES

SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap

(2008) A. D. Johnson et al.   BIOINFORMATICS