Involvement of Suppressive B-Lymphocytes in the Mechanism of Tolerogenic Dendritic Cell Reversal of Type 1 Diabetes in NOD Mice

B Lymphocyte Depletion by CD20 Monoclonal Antibody Prevents Diabetes in Nonobese Diabetic Mice despite Isotype-Specific Differences in Fc R Effector Functions

(2014) Y. Xiu et al.   JOURNAL OF IMMUNOLOGY

Advances in our understanding of the pathophysiology of Type 1 diabetes: lessons from the NOD mouse

(2013) Abhirup Jayasimhan et al.   CLINICAL SCIENCE

The targeting ofβ-cells by T lymphocytes in human type 1 diabetes: clinical perspectives

(2013) S. Luce et al.   DIABETES OBESITY & METABOLISM

Lymphodepletion and Homeostatic Proliferation: Implications for Transplantation

(2012) N. K. Tchao et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

B cells as effectors and regulators of autoimmunity

(2012) Eliana Mariño et al.   AUTOIMMUNITY

Essential roles of insulin expression in Aire+ tolerogenic dendritic cells in maintaining peripheral self-tolerance of islet β-cells

(2012) Maria Grupillo et al.   CELLULAR IMMUNOLOGY

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions

(2012) Ayumi Yoshizaki et al.   NATURE

Regulatory T-Cells: Diverse Phenotypes Integral to Immune Homeostasis and Suppression

(2012) Richard A. Peterson   TOXICOLOGIC PATHOLOGY

Interleukin-10 produced by B cells is crucial for the suppression of Th17/Th1 responses, induction of T regulatory type 1 cells and reduction of collagen-induced arthritis

(2012) Natalie A Carter et al.   ARTHRITIS RESEARCH & THERAPY

T cell-driven initiation and propagation of autoimmune diabetes

(2011) Maria Bettini et al.   CURRENT OPINION IN IMMUNOLOGY

Inotuzumab Ozogamicin Murine Analog-Mediated B-Cell Depletion Reduces Anti-islet Allo- and Autoimmune Responses

(2011) M. Carvello et al.   DIABETES

Phase I (Safety) Study of Autologous Tolerogenic Dendritic Cells in Type 1 Diabetic Patients

(2011) N. Giannoukakis et al.   DIABETES CARE

Beyond the Hormone: Insulin as an Autoimmune Target in Type 1 Diabetes

(2011) Vedran Brezar et al.   ENDOCRINE REVIEWS

Effect of rituximab on human in vivo antibody immune responses

(2011) Mark D. Pescovitz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mice Lacking Endogenous IL-10-Producing Regulatory B Cells Develop Exacerbated Disease and Present with an Increased Frequency of Th1/Th17 but a Decrease in Regulatory T Cells

(2011) N. A. Carter et al.   JOURNAL OF IMMUNOLOGY

Increased T Cell Proliferative Responses to Islet Antigens Identify Clinical Responders to Anti-CD20 Monoclonal Antibody (Rituximab) Therapy in Type 1 Diabetes

(2011) K. C. Herold et al.   JOURNAL OF IMMUNOLOGY

Regulatory B10 Cells Differentiate into Antibody-Secreting Cells After Transient IL-10 Production In Vivo

(2011) D. Maseda et al.   JOURNAL OF IMMUNOLOGY

Primary B cell repertoire remodeling to achieve humoral transplantation tolerance

(2011) Ronald F. Parsons et al.   SEMINARS IN IMMUNOLOGY

2011 Update

(2011) Aaron W. Michels et al.   Current Opinion in Endocrinology Diabetes and Obesity

B10 cells and regulatory B cells balance immune responses during inflammation, autoimmunity, and cancer

(2010) David J. DiLillo et al.   Annals of the New York Academy of Sciences

Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells

(2010) Y. Iwata et al.   BLOOD

B-cell tolerance: mechanisms and implications

(2010) Antony Basten et al.   CURRENT OPINION IN IMMUNOLOGY

Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass

(2010) B. Keymeulen et al.   DIABETOLOGIA

An update on the use of NOD mice to study autoimmune (Type 1) diabetes

(2010) Rodolfo José Chaparro et al.   Expert Review of Clinical Immunology

CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients

(2010) Paul A. Blair et al.   IMMUNITY

Molecular underpinning of B-cell anergy

(2010) Yuval Yarkoni et al.   IMMUNOLOGICAL REVIEWS

Development of Dendritic Cell-Based Immunotherapy for Autoimmunity

(2010) Catharien M. U. Hilkens et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Acquisition of Humoral Transplantation Tolerance upon De Novo Emergence of B Lymphocytes

(2010) R. F. Parsons et al.   JOURNAL OF IMMUNOLOGY

B1 Cells Promote Pancreas Infiltration by Autoreactive T Cells

(2010) G. A. Ryan et al.   JOURNAL OF IMMUNOLOGY

Regulatory B cells in autoimmunity: developments and controversies

(2010) Claudia Mauri et al.   Nature Reviews Rheumatology

Thymus-specific deletion of insulin induces autoimmune diabetes

(2009) Yong Fan et al.   EMBO JOURNAL

In vivo post-transcriptional regulation of CD154 in mouse CD4+ T cells

(2009) Stefano Vavassori et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Myeloid dendritic cell: From sentinel of immunity to key player of peripheral tolerance?

(2009) Kerstin Steinbrink et al.   HUMAN IMMUNOLOGY

Selected Toll-like Receptor Ligands and Viruses Promote Helper-Independent Cytotoxic T Cell Priming by Upregulating CD40L on Dendritic Cells

(2009) Susan Johnson et al.   IMMUNITY

Insights into the heterogeneity of human B cells: diverse functions, roles in autoimmunity, and use as therapeutic targets

(2009) Jennifer H. Anolik et al.   IMMUNOLOGIC RESEARCH

Novel Human Transitional B Cell Populations Revealed by B Cell Depletion Therapy

(2009) Arumugam Palanichamy et al.   JOURNAL OF IMMUNOLOGY

Selective Targeting of B Cells with Agonistic Anti-CD40 Is an Efficacious Strategy for the Generation of Induced Regulatory T2-Like B Cells and for the Suppression of Lupus in MRL/lpr Mice

(2009) P. A. Blair et al.   JOURNAL OF IMMUNOLOGY

B Cells and Immunological Tolerance

(2009) Nataly Manjarrez-Orduño et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

(2009) Masako Murai et al.   NATURE IMMUNOLOGY

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

(2009) Mark D. Pescovitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Expression of retinoic acid receptors in intestinal mucosa and the effect of vitamin A on mucosal immunity

(2009) Ping Dong et al.   NUTRITION

Anti-CD20 therapy in patients with rheumatoid arthritis: Predictors of response and B cell subset regeneration after repeated treatment

(2008) Petra Roll et al.   ARTHRITIS AND RHEUMATISM

Targeting CD22 Reprograms B-Cells and Reverses Autoimmune Diabetes

(2008) P. Fiorina et al.   DIABETES

A Regulatory B Cell Subset with a Unique CD1dhiCD5+ Phenotype Controls T Cell-Dependent Inflammatory Responses

(2008) Koichi Yanaba et al.   IMMUNITY

Role of retinoic acid in the imprinting of gut-homing IgA-secreting cells

(2008) J. Rodrigo Mora et al.   SEMINARS IN IMMUNOLOGY