Development of Dendritic Cell-Based Immunotherapy for Autoimmunity

Impact of Mammalian Target of Rapamycin Inhibition on Lymphoid Homing and Tolerogenic Function of Nanoparticle-Labeled Dendritic Cells following Allogeneic Hematopoietic Cell Transplantation

(2014) W. Reichardt et al.   JOURNAL OF IMMUNOLOGY

Lipopolysaccharide-Activated IL-10-Secreting Dendritic Cells Suppress Experimental Autoimmune Uveoretinitis by MHCII-Dependent Activation of CD62L-Expressing Regulatory T Cells

(2014) A. W. T. Lau et al.   JOURNAL OF IMMUNOLOGY

Plasmacytoid Dendritic Cells Regulate Breach of Self-Tolerance in Autoimmune Arthritis

(2014) S. L. Jongbloed et al.   JOURNAL OF IMMUNOLOGY

Suppression of Experimental Autoimmune Uveoretinitis by Regulatory Dendritic Cells in Mice

(2009) Yoshihiko Usui   ARCHIVES OF OPHTHALMOLOGY

Amphoteric liposomes enable systemic antigen-presenting cell-directed delivery of CD40 antisense and are therapeutically effective in experimental arthritis

(2009) Evangelos Andreakos et al.   ARTHRITIS AND RHEUMATISM

A novel in vivo siRNA delivery system specifically targeting dendritic cells and silencing CD40 genes for immunomodulation

(2009) X. Zheng et al.   BLOOD

Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity

(2009) Caspar Ohnmacht et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antigen-Specific Suppression of Inflammatory Arthritis Using Liposomes

(2009) C. Capini et al.   JOURNAL OF IMMUNOLOGY

A novel paradigm for dendritic cells as effectors of cartilage destruction

(2009) R. L. Lakey et al.   RHEUMATOLOGY

Rheumatoid Arthritis Synovium Contains Two Subsets of CD83−DC-LAMP− Dendritic Cells with Distinct Cytokine Profiles

(2008) M. Cristina Lebre et al.   AMERICAN JOURNAL OF PATHOLOGY

Increased frequency of CD16+ monocytes and the presence of activated dendritic cells in salivary glands in primary Sjogren syndrome

(2008) M E Wildenberg et al.   ANNALS OF THE RHEUMATIC DISEASES

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Tissue-targeted therapy of autoimmune diabetes using dendritic cells transduced to express IL-4 in NOD mice

(2008) Rémi J. Creusot et al.   CLINICAL IMMUNOLOGY

Lack of Conventional Dendritic Cells Is Compatible with Normal Development and T Cell Homeostasis, but Causes Myeloid Proliferative Syndrome

(2008) Tal Birnberg et al.   IMMUNITY

Plasmacytoid Dendritic Cells Mediate Oral Tolerance

(2008) Anne Goubier et al.   IMMUNITY

Dendritic cells modulated by innate immunity improve collagen-induced arthritis and induce regulatory T cellsin vivo

(2008) Olivier Jaen et al.   IMMUNOLOGY

Delivery of rapamycin to dendritic cells using degradable microparticles

(2008) S. Jhunjhunwala et al.   JOURNAL OF CONTROLLED RELEASE

Differential regulation of naïve and memory CD4+ T cells by alternatively activated dendritic cells

(2008) Amy E. Anderson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

LPS activation is required for migratory activity and antigen presentation by tolerogenic dendritic cells

(2008) A. E. Anderson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Dendritic cells transduced with lentiviral-mediated RelB-specific ShRNAs inhibit the development of experimental autoimmune myasthenia gravis

(2008) Yong Zhang et al.   MOLECULAR IMMUNOLOGY

Differential MHC class II synthesis and ubiquitination confers distinct antigen-presenting properties on conventional and plasmacytoid dendritic cells

(2008) Louise J Young et al.   NATURE IMMUNOLOGY

Selective delivery of   cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice

(2008) A. Mukhopadhaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A pilot study of combination anti-cytokine and anti-lymphocyte biological therapy in rheumatoid arthritis

(2008) A.W. Morgan et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

CTLA4-Ig-modified dendritic cells inhibit lymphocyte-mediated alloimmune responses and prolong the islet graft survival in mice

(2008) Dao-Feng Yang et al.   TRANSPLANT IMMUNOLOGY