Development of a Convenient In Vivo Hepatotoxin Assay Using a Transgenic Zebrafish Line with Liver-Specific DsRed Expression

HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: identification of bioactivable drugs and the potential mechanism of toxicity involved

(2013) Laia Tolosa et al.   ARCHIVES OF TOXICOLOGY

Fluorescent Transgenic Zebrafish Tg(nkx2.2a:mEGFP) Provides a Highly Sensitive Monitoring Tool for Neurotoxins

(2013) Xiaoyan Zhang et al.   PLoS One

Proteomic Analysis of Arsenic-Exposed Zebrafish (Danio rerio) Identifies Altered Expression in Proteins Involved in Fibrosis and Lipid Uptake in a Gender-Specific Manner

(2013) Patrick Carlson et al.   TOXICOLOGICAL SCIENCES

Toxicity assessments of nonsteroidal anti-inflammatory drugs in isolated mitochondria, rat hepatocytes, and zebrafish show good concordance across chemical classes

(2013) Sashi Nadanaciva et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A Chemical Screening Procedure for Glucocorticoid Signaling with a Zebrafish Larva Luciferase Reporter System

(2013) Benjamin D. Weger et al.   Jove-Journal of Visualized Experiments

Comparisons betweenin vitrowhole cell imaging andin vivozebrafish-based approaches for identifying potential human hepatotoxicants earlier in pharmaceutical development

(2012) Adrian Hill et al.   DRUG METABOLISM REVIEWS

Differential effects of estrogen/androgen on the prevention of nonalcoholic fatty liver disease in the male rat

(2012) Hua Zhang et al.   JOURNAL OF LIPID RESEARCH

Arsenic-induced biochemical and genotoxic effects and distribution in tissues of Sprague–Dawley rats

(2012) Anita K. Patlolla et al.   MICROCHEMICAL JOURNAL

Urinary and serum biomarkers for the diagnosis of acute kidney injury: an in-depth review of the literature*

(2012) Jill Vanmassenhove et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

A critical evaluation of in vitro cell culture models for high-throughput drug screening and toxicity

(2012) Anna Astashkina et al.   PHARMACOLOGY & THERAPEUTICS

Persistent organochlorinated pesticides and mechanisms of their toxicity

(2012) Ezra J. Mrema et al.   TOXICOLOGY

Animal models of idiosyncratic drug-induced liver injury—Current status

(2011) Robert A. Roth et al.   CRITICAL REVIEWS IN TOXICOLOGY

Assessment of nonsteroidal anti-inflammatory drug-induced hepatotoxicity

(2011) José AG Agúndez et al.   Expert Opinion on Drug Metabolism & Toxicology

Zebrafish for drug toxicity screening: bridging thein vitrocell-based models andin vivomammalian models

(2011) Hendrian Sukardi et al.   Expert Opinion on Drug Metabolism & Toxicology

Protective effect of gallic acid against lindane induced toxicity in experimental rats

(2011) V. Vijaya Padma et al.   FOOD AND CHEMICAL TOXICOLOGY

Molecular investigation of the effects of lindane in rat hepatocytes: Microarray and mechanistic studies

(2011) Nathalie Zucchini-Pascal et al.   FOOD AND CHEMICAL TOXICOLOGY

Liver tumor models in transgenic zebrafish: an alternativein vivoapproach to study hepatocarcinogenes

(2011) Xiaoqian Huang et al.   Future Oncology

The use of phenylbutazone in the horse

(2011) L. R. SOMA et al.   JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Hepatotoxicity related to antirheumatic drugs

(2011) Guruprasad P. Aithal   Nature Reviews Rheumatology

In vivo imaging and quantitative analysis of changes in axon length using transgenic zebrafish embryos

(2011) Jyotshnabala Kanungo et al.   NEUROTOXICOLOGY AND TERATOLOGY

Lindane Toxicity: A Comprehensive Review of the Medical Literature

(2011) Katherine Nolan et al.   PEDIATRIC DERMATOLOGY

Existence of Inverted Profile in Chemically Responsive Molecular Pathways in the Zebrafish Liver

(2011) Choong Yong Ung et al.   PLoS One

Atherosclerosis induced by arsenic in drinking water in rats through altering lipid metabolism

(2011) Tain-Junn Cheng et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Acetaminophen induced acute liver failure via oxidative stress and JNK activation: Protective role of taurine by the suppression of cytochrome P450 2E1

(2010) Joydeep Das et al.   FREE RADICAL RESEARCH

Estrogen Stimulates Proliferation and Differentiation of Neural Stem/Progenitor Cells through Different Signal Transduction Pathways

(2010) Makiko Okada et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury

(2010) T. E. North et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomarkers of alcohol consumption and related liver disease

(2010) Onni Niemelä et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Isoniazid-induced apoptosis in HepG2 cells: Generation of oxidative stress and Bcl-2 down-regulation

(2010) Smrati Bhadauria et al.   TOXICOLOGY MECHANISMS AND METHODS

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

Correlation of mRNA and protein in complex biological samples

(2009) Tobias Maier et al.   FEBS LETTERS

Oxidative stress in liver and red blood cells in acute lindane toxicity in rats

(2009) T. RadosavljeviĆ et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Zebrafish: a predictive model for assessing drug-induced toxicity

(2008) Patricia McGrath et al.   DRUG DISCOVERY TODAY

Hepatocellular adenoma: what is new in 2008

(2008) Paulette Bioulac-Sage et al.   Hepatology International

Uncovering Genes with Divergent mRNA-Protein Dynamics in Streptomyces coelicolor

(2008) Karthik P. Jayapal et al.   PLoS One