Zebrafish for drug toxicity screening: bridging thein vitrocell-based models andin vivomammalian models

Functional differences in the cytochrome P450 1 family enzymes from Zebrafish (Danio rerio) using heterologously expressed proteins

(2010) Marcus L. Scornaienchi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Morphological score assignment guidelines for the dechorionated zebrafish teratogenicity assay

(2010) Julieta M. Panzica-Kelly et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Development of a zebrafish embryo teratogenicity assay and quantitative prediction model

(2010) Kimberly C. Brannen et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

In vitro developmental toxicology assays: A review of the state of the science of rodent and zebrafish whole embryo culture and embryonic stem cell assays

(2010) Karen Augustine-Rauch et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Zebrafish as a Model for the Study of the Phase II Cytosolic Sulfotransferases

(2010) Tzu-An Liu et al.   CURRENT DRUG METABOLISM

The zebrafish embryo as a model for assessing off-target drug effects

(2010) U. Strahle et al.   Disease Models & Mechanisms

Drug screening for hearing loss: Using the zebrafish lateral line to screen for drugs that prevent and cause hearing loss

(2010) Henry C. Ou et al.   DRUG DISCOVERY TODAY

Visualizing voltage dynamics in zebrafish heart

(2010) Hidekazu Tsutsui et al.   JOURNAL OF PHYSIOLOGY-LONDON

Rapid behavior-based identification of neuroactive small molecules in the zebrafish

(2010) David Kokel et al.   Nature Chemical Biology

High-throughput in vivo vertebrate screening

(2010) Carlos Pardo-Martin et al.   NATURE METHODS

Locomotor activity in zebrafish embryos: A new method to assess developmental neurotoxicity

(2010) Ingrid W.T. Selderslaghs et al.   NEUROTOXICOLOGY AND TERATOLOGY

Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation

(2010) J. Rihel et al.   SCIENCE

Accumulation and metabolism of drugs and CYP probe substrates in zebrafish larvae

(2010) W. Alderton et al.   XENOBIOTICA

Incorporating Zebrafish Omics into Chemical Biology and Toxicology

(2010) Hendrian Sukardi et al.   Zebrafish

Oxidative and Conjugative Xenobiotic Metabolism in Zebrafish Larvae In Vivo

(2010) Huw S. Jones et al.   Zebrafish

Chemical Screening for Hair Cell Loss and Protection in the Zebrafish Lateral Line

(2010) Allison B. Coffin et al.   Zebrafish

Saltatory ontogeny of fishes and sensitive early life stages for ecotoxicology tests

(2009) Scott E. Belanger et al.   AQUATIC TOXICOLOGY

Noninvasive technique for measurement of heartbeat regularity in zebrafish (Danio rerio) embryos

(2009) Po Kwok Chan et al.   BMC BIOTECHNOLOGY

Normal table of postembryonic zebrafish development: Staging by externally visible anatomy of the living fish

(2009) David M. Parichy et al.   DEVELOPMENTAL DYNAMICS

The use ofin vivozebrafish assays in drug toxicity screening

(2009) Peter M Eimon et al.   Expert Opinion on Drug Metabolism & Toxicology

Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways

(2009) Kelly N. Owens et al.   HEARING RESEARCH

Identification of FDA-Approved Drugs and Bioactives that Protect Hair Cells in the Zebrafish (Danio rerio) Lateral Line and Mouse (Mus musculus) Utricle

(2009) Henry C. Ou et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Automated high-throughput mapping of promoter-enhancer interactions in zebrafish embryos

(2009) Jochen Gehrig et al.   NATURE METHODS

Gene expression changes in developing zebrafish as potential markers for rapid developmental neurotoxicity screening

(2009) Chun-Yang Fan et al.   NEUROTOXICOLOGY AND TERATOLOGY

Acute neuroactive drug exposures alter locomotor activity in larval zebrafish

(2009) T.D. Irons et al.   NEUROTOXICOLOGY AND TERATOLOGY

Zebrafish embryos as models for embryotoxic and teratological effects of chemicals

(2009) Lixin Yang et al.   REPRODUCTIVE TOXICOLOGY

A HESI consortium approach to assess the human predictive value of non-clinical repolarization assays

(2009) Elena S. Trepakova et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Zebrafish reward mutants reveal novel transcripts mediating the behavioral effects of amphetamine

(2009) Katharine J Webb et al.   GENOME BIOLOGY

State of the art in developmental toxicity screening methods and a way forward: a meeting report addressing embryonic stem cells, whole embryo culture, and zebrafish

(2008) Robert Chapin et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Is the fish embryo toxicity test (FET) with the zebrafish (Danio rerio) a potential alternative for the fish acute toxicity test?

(2008) E. Lammer et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Zebrafish: a predictive model for assessing drug-induced toxicity

(2008) Patricia McGrath et al.   DRUG DISCOVERY TODAY

The zebrafish embryo model in environmental risk assessment—applications beyond acute toxicity testing

(2008) Stefan Scholz et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Using the Zebrafish Lateral Line to Screen for Ototoxicity

(2008) Lynn L. Chiu et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Comparative genomics identifies genes mediating cardiotoxicity in the embryonic zebrafish heart

(2008) Jing Chen et al.   PHYSIOLOGICAL GENOMICS

Identification of a Novel Retinoid by Small Molecule Screening with Zebrafish Embryos

(2008) Chetana Sachidanandan et al.   PLoS One

Zebrafish assays as early safety pharmacology screens: Paradigm shift or red herring?

(2008) William S. Redfern et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Zebrafish based assays for the assessment of cardiac, visual and gut function — potential safety screens for early drug discovery

(2008) Stéphane Berghmans et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Zebrafish Whole-Adult-Organism Chemogenomics for Large-Scale Predictive and Discovery Chemical Biology

(2008) Siew Hong Lam et al.   PLoS Genetics

Evaluation of zebrafish embryos as a model for assessing inhibition of hERG

(2007) S.W. Mittelstadt et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS