Probenecid Blocks Human P2X7 Receptor-Induced Dye Uptake via a Pannexin-1 Independent Mechanism

P2X7 Receptor Activation Induces Reactive Oxygen Species Formation and Cell Death in Murine EOC13 Microglia

(2013) Rachael Bartlett et al.   MEDIATORS OF INFLAMMATION

Is pannexin the pore associated with the P2X7 receptor?

(2013) A. V. P. Alberto et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

CAY10593 inhibits the human P2X7 receptor independently of phospholipase D1 stimulation

(2013) A. Pupovac et al.   Purinergic Signalling

P2X7R: A potential key regulator of acute gouty arthritis

(2013) Jin-Hui Tao et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

TRPA1 Agonist Activity of Probenecid Desensitizes Channel Responses: Consequences for Screening

(2012) Conor McClenaghan et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Transient P2X 7 Receptor Activation Triggers Macrophage Death Independent of Toll-like Receptors 2 and 4, Caspase-1, and Pannexin-1 Proteins

(2012) Peter J. Hanley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P2X7 receptor activation mediates organic cation uptake into human myeloid leukaemic KG-1 cells

(2012) Safina Gadeock et al.   Purinergic Signalling

2012 American College of Rheumatology guidelines for management of gout. Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia

(2012) Dinesh Khanna et al.   ARTHRITIS CARE & RESEARCH

ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation

(2012) N Riteau et al.   Cell Death & Disease

Colchicine inhibits cationic dye uptake induced by ATP in P2X2 and P2X7 receptor-expressing cells: implications for its therapeutic action

(2011) C Marques-da-Silva et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pannexin-1 Is Required for ATP Release during Apoptosis but Not for Inflammasome Activation

(2011) Y. Qu et al.   JOURNAL OF IMMUNOLOGY

Probenecid Inhibits the Human Bitter Taste Receptor TAS2R16 and Suppresses Bitter Perception of Salicin

(2011) Tiffani A. Greene et al.   PLoS One

The human P2X7 receptor and its role in innate immunity

(2011) J. S. Wiley et al.   TISSUE ANTIGENS

Two haplotypes of the P2X7 receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1β secretion

(2010) Leanne Stokes et al.   FASEB JOURNAL

Mechanisms of uric acid crystal-mediated autoinflammation

(2009) Fabio Martinon   IMMUNOLOGICAL REVIEWS

Probenecid, a gout remedy, inhibits pannexin 1 channels

(2008) William Silverman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

ATP-induced P2X7-associated uptake of large molecules involves distinct mechanisms for cations and anions in macrophages

(2008) J. Schachter et al.   JOURNAL OF CELL SCIENCE

Pharmacological Characterization of Pannexin-1 Currents Expressed in Mammalian Cells

(2008) W. Ma et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1  and IL-18 secretion in an autocrine way

(2008) A. Piccini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of the human P2X7 receptor by a novel protein tyrosine kinase antagonist

(2007) Anne N. Shemon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS