Interferon-Beta Induces Distinct Gene Expression Response Patterns in Human Monocytes versus T cells

Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles

(2012) Benjamin P Fairfax et al.   NATURE GENETICS

An HNF4α-miRNA Inflammatory Feedback Circuit Regulates Hepatocellular Oncogenesis

(2011) Maria Hatziapostolou et al.   CELL

HMGB1, an alarmin promoting HIV dissemination and latency in dendritic cells

(2011) M-L Gougeon et al.   CELL DEATH AND DIFFERENTIATION

Taming of macrophage and microglial cell activation by microRNA-124

(2011) Ashley T Conrad et al.   CELL RESEARCH

Pharmacogenomics and Multiple Sclerosis: Moving Toward Individualized Medicine

(2011) Manuel Comabella et al.   Current Neurology and Neuroscience Reports

Contrasting effects of TNF and anti-TNF on the activation of effector T cells and regulatory T cells in autoimmunity

(2011) Xin Chen et al.   FEBS LETTERS

Dendritic cell vaccine therapy for acute myeloid leukemia: Questions and answers

(2011) Sébastien Anguille et al.   Human vaccines & immunotherapeutics

Cell death gene expression profile: Role of RIPK2 in dengue virus-mediated apoptosis

(2011) Atthapan Morchang et al.   VIRUS RESEARCH

HMGB1 and RAGE in Inflammation and Cancer

(2010) Gary P. Sims et al.   Annual Review of Immunology

The protective effects of paclitaxel on platelet aggregation through the inhibition of thromboxane A2 synthase

(2010) Jung-Jin Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Monocyte and Macrophage Abnormalities in Systemic Lupus Erythematosus

(2010) Yi Li et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Cathepsins and their endogenous inhibitors cystatins: expression and modulation in multiple sclerosis

(2010) Dana Haves-Zburof et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

IFN-  Inhibits Dendritic Cell Migration through STAT-1-Mediated Transcriptional Suppression of CCR7 and Matrix Metalloproteinase 9

(2010) J.-H. Yen et al.   JOURNAL OF IMMUNOLOGY

Major Differences in the Responses of Primary Human Leukocyte Subsets to IFN- 

(2010) A. H. H. van Boxel-Dezaire et al.   JOURNAL OF IMMUNOLOGY

Current and Future Role of Interferon Beta in the Therapy of Multiple Sclerosis

(2010) Rachel A. Farrell et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Ion channels in monocytes and microglia / brain macrophages: Promising therapeutic targets for neurological diseases

(2010) Claudia Eder   JOURNAL OF NEUROIMMUNOLOGY

Cathepsins (S and B) and their inhibitor Cystatin C in immune cells: Modulation by interferon-β and role played in cell migration

(2010) Elsebeth Staun-Ram et al.   JOURNAL OF NEUROIMMUNOLOGY

Gene expression in IFNß signalling pathway differs between monocytes, CD4 and CD8 T cells from MS patients

(2010) B. Oliver-Martos et al.   JOURNAL OF NEUROIMMUNOLOGY

MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway

(2010) Eugene D Ponomarev et al.   NATURE MEDICINE

Expander: from expression microarrays to networks and functions

(2010) Igor Ulitsky et al.   Nature Protocols

Tumor necrosis factor blockade and the risk of viral infection

(2010) Seo Young Kim et al.   Nature Reviews Rheumatology

SPIKE: a database of highly curated human signaling pathways

(2010) Arnon Paz et al.   NUCLEIC ACIDS RESEARCH

Long-term genome-wide blood RNA expression profiles yield novel molecular response candidates for IFN-β-1b treatment in relapsing remitting MS

(2010) Robert H Goertsches et al.   PHARMACOGENOMICS

Network analysis of transcriptional regulation in response to intramuscular interferon-β-1a multiple sclerosis treatment

(2010) M Hecker et al.   PHARMACOGENOMICS JOURNAL

Dissecting Interferon-Induced Transcriptional Programs in Human Peripheral Blood Cells

(2010) Simon J. Waddell et al.   PLoS One

Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation

(2010) Haining Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elevated plasma level of HMGB1 is associated with disease activity and combined alterations with IFN-alpha and TNF-alpha in systemic lupus erythematosus

(2010) Chun-yan Ma et al.   RHEUMATOLOGY INTERNATIONAL

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

A Critical Role for LTA4H in Limiting Chronic Pulmonary Neutrophilic Inflammation

(2010) R. J. Snelgrove et al.   SCIENCE

Type I IFN and TNFα cross-regulation in immune-mediated inflammatory disease: basic concepts and clinical relevance

(2010) Tineke Cantaert et al.   ARTHRITIS RESEARCH & THERAPY

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

(2009) Eran Eden et al.   BMC BIOINFORMATICS

Transcription Factor Achaete Scute-Like 2 Controls Intestinal Stem Cell Fate

(2009) Laurens G. van der Flier et al.   CELL

Vigorous activation of monocytes in juvenile autoimmune liver disease escapes the control of regulatory T-cells

(2009) Maria Serena Longhi et al.   HEPATOLOGY

Rubella vaccine-induced cellular immunity: evidence of associations with polymorphisms in the Toll-like, vitamin A and D receptors, and innate immune response genes

(2009) Inna G. Ovsyannikova et al.   HUMAN GENETICS

Interferons and autoimmune disorders

(2009) Olivier Meyer   JOINT BONE SPINE

Inflammatory Proprotein Convertase-Matrix Metalloproteinase Proteolytic Pathway in Antigen-presenting Cells as a Step to Autoimmune Multiple Sclerosis

(2009) Sergey A. Shiryaev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macrophage Migration Inhibitory Factor Homologs of Anisakis simplex Suppress Th2 Response in Allergic Airway Inflammation Model via CD4+CD25+Foxp3+ T Cell Recruitment

(2009) S. K. Park et al.   JOURNAL OF IMMUNOLOGY

Effect of IFN-ß therapy on the frequency and function of CD4+CD25+ regulatory T cells and Foxp3 gene expression in relapsing–remitting multiple sclerosis (RRMS): A preliminary study

(2009) Afshin Namdar et al.   JOURNAL OF NEUROIMMUNOLOGY

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

(2009) Hideyuki Yanai et al.   NATURE

The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules

(2009) Shengli Hao et al.   NATURE IMMUNOLOGY

Interferon-  mechanisms of action in multiple sclerosis

(2009) S. Dhib-Jalbut et al.   NEUROLOGY

Longitudinal system-based analysis of transcriptional responses to type I interferons

(2009) D. J. Pappas et al.   PHYSIOLOGICAL GENOMICS

CD24 and Siglec-10 Selectively Repress Tissue Damage-Induced Immune Responses

(2009) G.-Y. Chen et al.   SCIENCE

Pivotal Advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis

(2008) Åsa Andersson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Genomic effects of once-weekly, intramuscular interferon-β1a treatment after the first dose and on chronic dosing: Relationships to 5-year clinical outcomes in multiple sclerosis patients

(2008) Bianca Weinstock-Guttman et al.   JOURNAL OF NEUROIMMUNOLOGY

The Addition of Tumor Necrosis Factor plus Beta Interferon Induces a Novel Synergistic Antiviral State against Poxviruses in Primary Human Fibroblasts

(2008) E. Bartee et al.   JOURNAL OF VIROLOGY

Evolution and Function of the ADP Ribosyl Cyclase/CD38 Gene Family in Physiology and Pathology

(2008) Fabio Malavasi et al.   PHYSIOLOGICAL REVIEWS

Pharmacogenomics of Interferon-ß Therapy in Multiple Sclerosis: Baseline IFN Signature Determines Pharmacological Differences between Patients

(2008) Lisa G. M. van Baarsen et al.   PLoS One

CD83 regulates lymphocyte maturation, activation and homeostasis

(2008) Minka Breloer et al.   TRENDS IN IMMUNOLOGY

Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy

(2007) Ronald J Buckanovich et al.   NATURE MEDICINE