Long-term genome-wide blood RNA expression profiles yield novel molecular response candidates for IFN-β-1b treatment in relapsing remitting MS

Systems biology and its application to the understanding of neurological diseases

(2009) Pablo Villoslada et al.   ANNALS OF NEUROLOGY

Integrative modeling of transcriptional regulation in response to antirheumatic therapy

(2009) Michael Hecker et al.   BMC BIOINFORMATICS

A type I interferon signature in monocytes is associated with poor response to interferon-β in multiple sclerosis

(2009) M. Comabella et al.   BRAIN

CXCL10 Impairs β Cell Function and Viability in Diabetes through TLR4 Signaling

(2009) Fabienne T. Schulthess et al.   Cell Metabolism

Monitoring of multiple sclerosis immunotherapy

(2009) Robert H. Goertsches et al.   JOURNAL OF NEUROLOGY

Absence of MxA induction by interferon   in patients with MS reflects complete loss of bioactivity

(2009) D. Hesse et al.   NEUROLOGY

Free Fatty Acid Receptors and Drug Discovery

(2008) Akira Hirasawa et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Interferon-β increases BAFF levels in multiple sclerosis: implications for B cell autoimmunity

(2008) M. Krumbholz et al.   BRAIN

Systems biology approaches for the study of multiple sclerosis

(2008) Francisco J. Quintana et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

IFN-β1b Induces Transient and Variable Gene Expression in Relapsing-Remitting Multiple Sclerosis Patients Independent of Neutralizing Antibodies or Changes in IFN Receptor RNA Expression

(2008) Anthony T. Reder et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Biological response genes after single dose administration of interferon β-1b to healthy male volunteers

(2008) Jan Hilpert et al.   JOURNAL OF NEUROIMMUNOLOGY

Genomic effects of once-weekly, intramuscular interferon-β1a treatment after the first dose and on chronic dosing: Relationships to 5-year clinical outcomes in multiple sclerosis patients

(2008) Bianca Weinstock-Guttman et al.   JOURNAL OF NEUROIMMUNOLOGY

Basic and escalating immunomodulatory treatments in multiple sclerosis: Current therapeutic recommendations

(2008) et al.   JOURNAL OF NEUROLOGY

Pharmacogenomics of the response to IFN-β in multiple sclerosis: ramifications from the first genome-wide screen

(2008) Koen Vandenbroeck et al.   PHARMACOGENOMICS

Pharmacogenomics of Interferon-ß Therapy in Multiple Sclerosis: Baseline IFN Signature Determines Pharmacological Differences between Patients

(2008) Lisa G. M. van Baarsen et al.   PLoS One