Growth-Promoting Role of the miR-106a∼363 Cluster in Ewing Sarcoma

A TARBP2-Dependent miRNA Expression Profile Underlies Cancer Stem Cell Properties and Provides Candidate Therapeutic Reagents in Ewing Sarcoma

(2012) Claudio De Vito et al.   CANCER CELL

Cisplatin Sensitivity Mediated by WEE1 and CHK1 Is Mediated by miR-155 and the miR-15 Family

(2012) L. M. Pouliot et al.   CANCER RESEARCH

Vector-based miR-15a/16-1 plasmid inhibits colon cancer growthin vivo

(2012) Lixia Dai et al.   CELL BIOLOGY INTERNATIONAL

Involvement of microRNA-93, a new regulator of PTEN/Akt signaling pathway, in regulation of chemotherapeutic drug cisplatin chemosensitivity in ovarian cancer cells

(2012) Xin Fu et al.   FEBS LETTERS

Discovering the first microRNA-targeted drug

(2012) Morten Lindow et al.   JOURNAL OF CELL BIOLOGY

Synthetic lethality between Rb, p53 and Dicer or miR-17–92 in retinal progenitors suppresses retinoblastoma formation

(2012) David Nittner et al.   NATURE CELL BIOLOGY

miR-15a/16-1 influences BCL2 expression in keratocystic odontogenic tumors

(2012) Marina Gonçalves Diniz et al.   CELLULAR ONCOLOGY

Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia

(2011) D. Sampath et al.   BLOOD

Investigation of the insulin-like growth factor-1 signaling pathway in localized Ewing sarcoma

(2011) Scott C. Borinstein et al.   CANCER

Mouse miRNA-709 directly regulates miRNA-15a/16-1 biogenesis at the posttranscriptional level in the nucleus: evidence for a microRNA hierarchy system

(2011) Rui Tang et al.   CELL RESEARCH

Genomic and Clinical Analysis of Amplification of the 13q31 Chromosomal Region in Alveolar Rhabdomyosarcoma: A Report from the Children's Oncology Group

(2011) Jennifer L. Reichek et al.   CLINICAL CANCER RESEARCH

Nucleolin Protein Interacts with Microprocessor Complex to Affect Biogenesis of MicroRNAs 15a and 16

(2011) Brian F. Pickering et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy

(2011) Fumihiko Nakatani et al.   JOURNAL OF PATHOLOGY

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

Hsa-mir-145 is the top EWS-FLI1-repressed microRNA involved in a positive feedback loop in Ewing's sarcoma

(2011) J Ban et al.   ONCOGENE

A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAs

(2011) E L McKinsey et al.   ONCOGENE

Overexpression of MicroRNAs from the miR-17-92 Paralog Clusters in AIDS-Related Non-Hodgkin's Lymphomas

(2011) Dharma R. Thapa et al.   PLoS One

Let-7a Is a Direct EWS-FLI-1 Target Implicated in Ewing's Sarcoma Development

(2011) Claudio De Vito et al.   PLoS One

Modulation of Glucose Transporter 1 (GLUT1) Expression Levels Alters Mouse Mammary Tumor Cell Growth In Vitro and In Vivo

(2011) Christian D. Young et al.   PLoS One

R1507, an Anti-Insulin-Like Growth Factor-1 Receptor (IGF-1R) Antibody, and EWS/FLI-1 siRNA in Ewing's Sarcoma: Convergence at the IGF/IGFR/Akt Axis

(2011) Helen J. Huang et al.   PLoS One

Regulation of mRNA Translation and Stability by microRNAs

(2010) Marc Robert Fabian et al.   Annual Review of Biochemistry

The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia

(2010) Ulf Klein et al.   CANCER CELL

The Myc-miR-17 92 Axis Blunts TGF  Signaling and Production of Multiple TGF -Dependent Antiangiogenic Factors

(2010) M. Dews et al.   CANCER RESEARCH

Ewing sarcoma: historical perspectives, current state-of-the-art, and opportunities for targeted therapy in the future

(2010) Joseph A Ludwig   CURRENT OPINION IN ONCOLOGY

mir-17-92, a cluster of miRNAs in the midst of the cancer network

(2010) Virginie Olive et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Current Treatment Protocols Have Eliminated the Prognostic Advantage of Type 1 Fusions in Ewing Sarcoma: A Report From the Children's Oncology Group

(2010) John A. van Doorninck et al.   JOURNAL OF CLINICAL ONCOLOGY

Multiple E2F-Induced MicroRNAs Prevent Replicative Stress in Response to Mitogenic Signaling

(2010) M. J. Bueno et al.   MOLECULAR AND CELLULAR BIOLOGY

Efficient in vivo microRNA targeting of liver metastasis

(2010) C Huynh et al.   ONCOGENE

Recent advances in the molecular pathogenesis of Ewing's sarcoma

(2010) E C Toomey et al.   ONCOGENE

MicroRNA sponges: Progress and possibilities

(2010) M. S. Ebert et al.   RNA

Identification of the miR-106b 25 MicroRNA Cluster as a Proto-Oncogenic PTEN-Targeting Intron That Cooperates with Its Host Gene MCM7 in Transformation

(2010) L. Poliseno et al.   Science Signaling

miR-106a–mediated Malignant Transformation of Cells Induced by Anti-benzo[a]pyrene-trans-7,8-diol-9,10-epoxide

(2010) Yiguo Jiang et al.   TOXICOLOGICAL SCIENCES

Ewing’s sarcoma origin: from duel to duality

(2009) Nicolo Riggi et al.   Expert Review of Anticancer Therapy

The microRNA miR-92 increases proliferation of myeloid cells and by targeting p63 modulates the abundance of its isoforms

(2009) Isabella Manni et al.   FASEB JOURNAL

The miR-106b-25 Polycistron, Activated by Genomic Amplification, Functions as an Oncogene by Suppressing p21 and Bim

(2009) Takatsugu Kan et al.   GASTROENTEROLOGY

Genetic dissection of the miR-17 92 cluster of microRNAs in Myc-induced B-cell lymphomas

(2009) P. Mu et al.   GENES & DEVELOPMENT

miR-19 is a key oncogenic component of mir-17-92

(2009) V. Olive et al.   GENES & DEVELOPMENT

Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell

(2009) G. Sotiropoulou et al.   RNA

E2F1-Regulated MicroRNAs Impair TGFβ-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer

(2008) Fabio Petrocca et al.   CANCER CELL

Emerging Role of miR-106b-25/miR-17-92 Clusters in the Control of Transforming Growth Factor   Signaling

(2008) F. Petrocca et al.   CANCER RESEARCH

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

(2008) Andrea Ventura et al.   CELL

Locked Nucleic Acid Holds Promise in the Treatment of Cancer

(2008) Miriam Frieden et al.   CURRENT PHARMACEUTICAL DESIGN

Changes in Incidence and Survival of Ewing Sarcoma Patients Over the Past 3 Decades

(2008) Natia Esiashvili et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

(2008) Désirée Bonci et al.   NATURE MEDICINE

miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes

(2008) Q. Liu et al.   NUCLEIC ACIDS RESEARCH