miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy

An interview with Dr. Heiko Hermeking on his highly cited paper published inCell Cycle

(2011) Heiko Hermeking   CELL CYCLE

Nonmetastatic Ewing family tumors: high-dose chemotherapy with stem cell rescue in poor responder patients. Results of the Italian Sarcoma Group/Scandinavian Sarcoma Group III protocol

(2010) S. Ferrari et al.   ANNALS OF ONCOLOGY

Inhibition of the transcriptional function of p53 by EWS–Fli1 chimeric protein in Ewing Family Tumors

(2010) Yan Li et al.   CANCER LETTERS

Development of a Lung Cancer Therapeutic Based on the Tumor Suppressor MicroRNA-34

(2010) J. F. Wiggins et al.   CANCER RESEARCH

Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer

(2010) Dmitri Lodygin et al.   CELL CYCLE

Nutlin-3a Is a Potential Therapeutic for Ewing Sarcoma

(2010) K. I. Pishas et al.   CLINICAL CANCER RESEARCH

Intercohort Gene Expression Co-Analysis Reveals Chemokine Receptors as Prognostic Indicators in Ewing's Sarcoma

(2010) I. M. Bennani-Baiti et al.   CLINICAL CANCER RESEARCH

Micromarkers: miRNAs in cancer diagnosis and prognosis

(2010) Manuela Ferracin et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

miRNAs as molecular biomarkers of cancer

(2010) Muller Fabbri   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Approaching Ewing sarcoma

(2010) Uta Dirksen et al.   Future Oncology

EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells

(2010) N. Riggi et al.   GENES & DEVELOPMENT

Robust one-day in situ hybridization protocol for detection of microRNAs in paraffin samples using LNA probes

(2010) Stine Jørgensen et al.   METHODS

Functional elucidation of MiR-34 in osteosarcoma cells and primary tumor samples

(2009) Chunlei He et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bone and soft tissue sarcomas are often curable-But at what cost?

(2009) Ronald D. Barr et al.   CANCER

Identification of Cancer Stem Cells in Ewing's Sarcoma

(2009) M.-L. Suva et al.   CANCER RESEARCH

The miR-34 family in cancer and apoptosis

(2009) H Hermeking   CELL DEATH AND DIFFERENTIATION

MicroRNAs: Predictors and modifiers of chemo- and radiotherapy in different tumour types

(2009) Richard Hummel et al.   EUROPEAN JOURNAL OF CANCER

Molecular characterization of commonly used cell lines for bone tumor research: A trans-European EuroBoNet effort

(2009) Laura Ottaviano et al.   GENES CHROMOSOMES & CANCER

MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells

(2009) Qing Ji et al.   PLoS One

Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy

(2008) Sanjeev Shangary et al.   Annual Review of Pharmacology and Toxicology

Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells

(2008) Yasunori Fujita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

miR-34a as part of the resistance network in chronic lymphocytic leukemia

(2008) T. Zenz et al.   BLOOD

Nutlin-3a Activates p53 to Both Down-regulate Inhibitor of Growth 2 and Up-regulate mir-34a, mir-34b, and mir-34c Expression, and Induce Senescence

(2008) K. Kumamoto et al.   CANCER RESEARCH

Microarray analysis of Ewing’s sarcoma family of tumours reveals characteristic gene expression signatures associated with metastasis and resistance to chemotherapy

(2008) Karl-Ludwig Schaefer et al.   EUROPEAN JOURNAL OF CANCER

Normalization of microRNA expression levels in quantitative RT-PCR assays: Identification of suitable reference RNA targets in normal and cancerous human solid tissues

(2008) H. J. Peltier et al.   RNA