Does fibrin(ogen) bind to monomeric or dimeric GPVI, or not at all?

Platelets Drive Thrombus Propagation in a Hematocrit and Glycoprotein VI–Dependent Manner in an In Vitro Venous Thrombosis ModelHighlights

(2018) Marcus Lehmann et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Immobilized fibrinogen activates human platelets through glycoprotein VI

(2018) Pierre H Mangin et al.   HAEMATOLOGICA

A fibrin biofilm covers blood clots and protects from microbial invasion

(2018) Fraser L. Macrae et al.   JOURNAL OF CLINICAL INVESTIGATION

Platelet collagen receptor Glycoprotein VI-dimer recognizes fibrinogen and fibrin through their D-domains, contributing to platelet adhesion and activation during thrombus formation

(2018) I. Induruwa et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Dimeric Glycoprotein VI Binds to Collagen but Not to Fibrin

(2018) Mariam Ebrahim et al.   THROMBOSIS AND HAEMOSTASIS

Immobilized fibrinogen activates human platelets through glycoprotein VI

(2018) Pierre H Mangin et al.   HAEMATOLOGICA

Clustering of glycoprotein VI (GPVI) dimers upon adhesion to collagen as a mechanism to regulate GPVI signaling in platelets

(2017) N. S. Poulter et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet Control of Fibrin Distribution and Microelasticity in Thrombus Formation Under FlowSignificance

(2016) Frauke Swieringa et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Factor XIII: Structure and Function

(2016) Hans Kohler et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

The use of SMALPs as a novel membrane protein scaffold for structure study by negative stain electron microscopy

(2015) Vincent Postis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Platelet glycoprotein VI binds to polymerized fibrin and promotes thrombin generation

(2015) E. Mammadova-Bach et al.   BLOOD

Fibrin activates GPVI in human and mouse platelets

(2015) O. M. Alshehri et al.   BLOOD

The Role of Laparoscopic Surgery in the Management of Children and Adolescents With Inflammatory Bowel Disease

(2015) Anna E. Page et al.   MEDICINE

A systems approach to hemostasis: 1. The interdependence of thrombus architecture and agonist movements in the gaps between platelets

(2014) J. D. Welsh et al.   BLOOD

A systems approach to hemostasis: 3. Thrombus consolidation regulates intrathrombus solute transport and local thrombin activity

(2014) T. J. Stalker et al.   BLOOD

A systems approach to hemostasis: 2. Computational analysis of molecular transport in the thrombus microenvironment

(2014) M. Tomaiuolo et al.   BLOOD

d-Dimer elevation and adverse outcomes

(2014) Rim Halaby et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Non-specific binding in solid phase immunoassays for autoantibodies correlates with inflammation markers

(2013) Esin Güven et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Constitutive Dimerization of Glycoprotein VI (GPVI) in Resting Platelets Is Essential for Binding to Collagen and Activation in Flowing Blood

(2012) Stephanie M. Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct and overlapping functional roles of Src family kinases in mouse platelets

(2012) S. SÉVERIN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet Glycoprotein VI Dimerization, an Active Process Inducing Receptor Competence, Is an Indicator of Platelet Reactivity

(2011) Stéphane Loyau et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Novel Antiplatelet Drug Revacept (Dimeric Glycoprotein VI-Fc) Specifically and Efficiently Inhibited Collagen-Induced Platelet Aggregation Without Affecting General Hemostasis in Humans

(2011) Martin Ungerer et al.   CIRCULATION

Collagen Structure and Stability

(2009) Matthew D. Shoulders et al.   Annual Review of Biochemistry

Crystal Structure of Human Fibrinogen

(2009) Justin M. Kollman et al.   BIOCHEMISTRY

Crystal structure and collagen-binding site of immune inhibitory receptor LAIR-1: unexpected implications for collagen binding by platelet receptor GPVI

(2009) T. H. C. Brondijk et al.   BLOOD

Glycoprotein (GP) VI dimer as a major collagen-binding site of native platelets: direct evidence obtained with dimeric GPVI-specific Fabs

(2009) S. M. JUNG et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Measuring soluble platelet glycoprotein VI in human plasma by ELISA

(2009) Mohammad Al-Tamimi et al.   PLATELETS

Compromised ITAM-based platelet receptor function in a patient with immune thrombocytopenic purpura

(2008) E. E. GARDINER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS