Clustering of glycoprotein VI (GPVI) dimers upon adhesion to collagen as a mechanism to regulate GPVI signaling in platelets

Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires Integrin αIIbβ3 and Lyn Kinase

(2015) Huiying Zhi et al.   PLoS One

Normal Activation of Discoidin Domain Receptor 1 Mutants with Disulfide Cross-links, Insertions, or Deletions in the Extracellular Juxtamembrane Region

(2014) Huifang Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Syk and Src Family Kinases Regulate C-type Lectin Receptor 2 (CLEC-2)-mediated Clustering of Podoplanin and Platelet Adhesion to Lymphatic Endothelial Cells

(2014) Alice Y. Pollitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic analysis of platelet deposition to resolve platelet adhesion receptor activity in whole blood at arterial shear rate

(2014) Nicholas Pugh et al.   PLATELETS

Constitutive Dimerization of Glycoprotein VI (GPVI) in Resting Platelets Is Essential for Binding to Collagen and Activation in Flowing Blood

(2012) Stephanie M. Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Platelet Glycoprotein VI Dimerization, an Active Process Inducing Receptor Competence, Is an Indicator of Platelet Reactivity

(2011) Stéphane Loyau et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Syk-kinase inhibitor R406 impairs platelet activation and monocyte tissue factor expression triggered by heparin-PF4 complex directed antibodies

(2011) T. LHERMUSIER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A New Wave of Cellular Imaging

(2010) Derek Toomre et al.   Annual Review of Cell and Developmental Biology

Synergism between platelet collagen receptors defined using receptor-specific collagen-mimetic peptide substrata in flowing blood

(2010) N. Pugh et al.   BLOOD

Spatial organization of transmembrane receptor signalling

(2010) Ioanna Bethani et al.   EMBO JOURNAL

An Important Role of the Src Family Kinase Lyn in Stimulating Platelet Granule Secretion

(2010) Zhenyu Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PALM imaging and cluster analysis of protein heterogeneity at the cell surface

(2010) Dylan M. Owen et al.   Journal of Biophotonics

GPVI and CLEC-2 in hemostasis and vascular integrity

(2010) S. P. WATSON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Oligomeric forms of G protein-coupled receptors (GPCRs)

(2010) Krzysztof Palczewski   TRENDS IN BIOCHEMICAL SCIENCES

Crystal structure and collagen-binding site of immune inhibitory receptor LAIR-1: unexpected implications for collagen binding by platelet receptor GPVI

(2009) T. H. C. Brondijk et al.   BLOOD

Integrin αIIbβ3 Activation in Chinese Hamster Ovary Cells and Platelets Increases Clustering Rather than Affinity

(2009) Thomas A. Bunch   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insights into the Interactions between Platelet Receptors and Fibrillar Collagen

(2009) Andrew B. Herr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycoprotein (GP) VI dimer as a major collagen-binding site of native platelets: direct evidence obtained with dimeric GPVI-specific Fabs

(2009) S. M. JUNG et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Identification of a major GpVI-binding locus in human type III collagen

(2008) G. E. Jarvis et al.   BLOOD