Wnt5A promotes an adaptive, senescent-like stress response, while continuing to drive invasion in melanoma cells

Molecular Pathways: BRAF Induces Bioenergetic Adaptation by Attenuating Oxidative Phosphorylation

(2014) R. Haq et al.   CLINICAL CANCER RESEARCH

WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors

(2014) Jamie N. Anastas et al.   JOURNAL OF CLINICAL INVESTIGATION

Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma

(2014) Chong Sun et al.   NATURE

Vemurafenib Induces Senescence Features in Melanoma Cells

(2013) Sebastian Haferkamp et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy

(2013) Jan R. Dörr et al.   NATURE

Hypoxia Induces Phenotypic Plasticity and Therapy Resistance in Melanoma via the Tyrosine Kinase Receptors ROR1 and ROR2

(2013) M. P. O'Connell et al.   Cancer Discovery

Suppression of Nucleotide Metabolism Underlies the Establishment and Maintenance of Oncogene-Induced Senescence

(2013) Katherine M. Aird et al.   Cell Reports

Wnt/ -Catenin Signaling and AXIN1 Regulate Apoptosis Triggered by Inhibition of the Mutant Kinase BRAFV600E in Human Melanoma

(2012) T. L. Biechele et al.   Science Signaling

Senescence: a new weapon for cancer therapy

(2012) Juan Carlos Acosta et al.   TRENDS IN CELL BIOLOGY

Wnt5a Suppresses Epithelial Ovarian Cancer by Promoting Cellular Senescence

(2011) B. G. Bitler et al.   CANCER RESEARCH

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

(2011) Paul B. Chapman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching

(2011) Ossia M. Eichhoff et al.   Pigment Cell & Melanoma Research

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescence

(2010) Pavel Krejci et al.   BONE

Microphthalmia-Associated Transcription Factor Controls the DNA Damage Response and a Lineage-Specific Senescence Program in Melanomas

(2010) Sandy Giuliano et al.   CANCER RESEARCH

Mina Bissell: Context is everything

(2009) Ben Short   JOURNAL OF CELL BIOLOGY

Wnt5A Activates the Calpain-Mediated Cleavage of Filamin A

(2009) Michael P. O'Connell et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Senescence induction; a possible cancer therapy

(2009) Matilde E LLeonart et al.   Molecular Cancer

The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

(2009) M P O’Connell et al.   ONCOGENE

p16INK4a-induced senescence is disabled by melanoma-associated mutations

(2008) Sebastian Haferkamp et al.   AGING CELL

Wnt5A Regulates Expression of Tumor-Associated Antigens in Melanoma via Changes in Signal Transducers and Activators of Transcription 3 Phosphorylation

(2008) S. K. Dissanayake et al.   CANCER RESEARCH