Synthetic lethal metabolic targeting of cellular senescence in cancer therapy

High-throughput SNP-based authentication of human cell lines

(2012) Felipe Castro et al.   INTERNATIONAL JOURNAL OF CANCER

Deregulated MYC expression induces dependence upon AMPK-related kinase 5

(2012) Lidan Liu et al.   NATURE

Opposing roles of NF- B in anti-cancer treatment outcome unveiled by cross-species investigations

(2011) H. Jing et al.   GENES & DEVELOPMENT

Control of the senescence-associated secretory phenotype by NF- B promotes senescence and enhances chemosensitivity

(2011) Y. Chien et al.   GENES & DEVELOPMENT

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

(2011) Tae-Won Kang et al.   NATURE

Corn hybrids display lower metabolite variability and complex metabolite inheritance patterns

(2011) Jan Lisec et al.   PLANT JOURNAL

Tumor Stroma-Derived TGF-β Limits Myc-Driven Lymphomagenesis via Suv39h1-Dependent Senescence

(2010) Maurice Reimann et al.   CANCER CELL

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

Risk-Adapted Dose-Dense Immunochemotherapy Determined by Interim FDG-PET in Advanced-Stage Diffuse Large B-Cell Lymphoma

(2010) Craig H. Moskowitz et al.   JOURNAL OF CLINICAL ONCOLOGY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells

(2010) M. G. Vander Heiden et al.   SCIENCE

TargetSearch - a Bioconductor package for the efficient preprocessing of GC-MS metabolite profiling data

(2009) Álvaro Cuadros-Inostroza et al.   BMC BIOINFORMATICS

Autophagy mediates the mitotic senescence transition

(2009) A. R.J. Young et al.   GENES & DEVELOPMENT

An automated GCxGC-TOF-MS protocol for batch-wise extraction and alignment of mass isotopomer matrixes from differential13C-labelling experiments: a case study for photoautotrophic-mixotrophic grownChlamydomonas reinhardtiicells

(2009) Stefan Kempa et al.   JOURNAL OF BASIC MICROBIOLOGY

High-Resolution Direct Infusion-Based Mass Spectrometry in Combination with Whole13C Metabolome Isotope Labeling Allows Unambiguous Assignment of Chemical Sum Formulas

(2008) Patrick Giavalisco et al.   ANALYTICAL CHEMISTRY

Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network

(2008) Thomas Kuilman et al.   CELL

Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence

(2008) Juan C. Acosta et al.   CELL

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY