Oleanolic acid inhibits cell survival and proliferation of prostate cancer cells in vitro and in vivo through the PI3K/Akt pathway

Smac mimetic and oleanolic acid synergize to induce cell death in human hepatocellular carcinoma cells

(2015) Juliane Liese et al.   CANCER LETTERS

Overexpression of lysine-specific demethylase 1 promotes androgen-independent transition of human prostate cancer LNCaP cells through activation of the AR signaling pathway and suppression of the p53 signaling pathway

(2015) XUECHAO LI et al.   ONCOLOGY REPORTS

PI3K/AKT signaling pathway and cancer: an updated review

(2014) Miriam Martini et al.   ANNALS OF MEDICINE

Oleanolic acid suppresses the proliferation of lung carcinoma cells by miR-122/Cyclin G1/MEF2D axis

(2014) Xiaoming Zhao et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Melatonin Improves Mitochondrial Function by Promoting MT1/SIRT1/PGC-1 Alpha-Dependent Mitochondrial Biogenesis in Cadmium-Induced Hepatotoxicity In Vitro

(2014) Pan Guo et al.   TOXICOLOGICAL SCIENCES

Posttranslational regulation of Akt in human cancer

(2014) Chia-Hsin Chan et al.   Cell and Bioscience

Inhibitory effect of oleanolic acid on hepatocellular carcinoma via ERK–p53-mediated cell cycle arrest and mitochondrial-dependent apoptosis

(2013) Xin Wang et al.   CARCINOGENESIS

Targeting the Akt Kinase to Modulate Survival, Invasiveness and Drug Resistance of Cancer Cells

(2013) Giuliana Cassinelli et al.   CURRENT MEDICINAL CHEMISTRY

Biochemical Basis of the Antidiabetic Activity of Oleanolic Acid and Related Pentacyclic Triterpenes

(2013) J. M. Castellano et al.   DIABETES

Targeting cell cycle regulation in cancer therapy

(2013) Santiago Diaz-Moralli et al.   PHARMACOLOGY & THERAPEUTICS

Oleanolic Acid Suppresses Migration and Invasion of Malignant Glioma Cells by Inactivating MAPK/ERK Signaling Pathway

(2013) Guocai Guo et al.   PLoS One

Oleanolic acid arrests cell cycle and induces apoptosis via ROS-mediated mitochondrial depolarization and lysosomal membrane permeabilization in human pancreatic cancer cells

(2012) Jianteng Wei et al.   JOURNAL OF APPLIED TOXICOLOGY

Oleanolic acid

(2012) Jacob Pollier et al.   PHYTOCHEMISTRY

Synthetic triterpenoid CDDO prevents the progression and metastasis of prostate cancer in TRAMP mice by inhibiting survival signaling

(2011) Dorrah Deeb et al.   CARCINOGENESIS

Clever cancer strategies with FoxO transcription factors

(2011) Kenneth Maiese et al.   CELL CYCLE

Akt signalling in health and disease

(2011) Ingeborg Hers et al.   CELLULAR SIGNALLING

Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics

(2011) Jean-Claude Martinou et al.   DEVELOPMENTAL CELL

Apoptosis in cancer: from pathogenesis to treatment

(2011) Rebecca SY Wong   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

PrimerBank: a PCR primer database for quantitative gene expression analysis, 2012 update

(2011) X. Wang et al.   NUCLEIC ACIDS RESEARCH

Oleanolic Acid Initiates Apoptosis in Non-Small Cell Lung Cancer Cell Lines and Reduces Metastasis of a B16F10 Melanoma Model In Vivo

(2011) Kelly Araújo Lúcio et al.   PLoS One

Prevention of Prostate Cancer with Oleanane Synthetic Triterpenoid CDDO-Me in the TRAMP Mouse Model of Prostate Cancer

(2011) Xiaohua Gao et al.   Cancers

Nonesterified cholesterol content of lysosomes modulates susceptibility to oxidant-induced permeabilization

(2010) John J. Reiners et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oleanolic Acid and Ursolic Acid Induce Apoptosis in HuH7 Human Hepatocellular Carcinoma Cells through a Mitochondrial-Dependent Pathway and Downregulation of XIAP

(2010) Ming-Huan Shyu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antioxidant, Antiproliferative, and Pro-apoptotic Capacities of Pentacyclic Triterpenes Found in the Skin of Olives on MCF-7 Human Breast Cancer Cells and Their Effects on DNA Damage

(2010) Yosra Allouche et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells through a ROS-dependent mechanism

(2009) Dorrah Deeb et al.   BIOCHEMICAL PHARMACOLOGY

Bcl-2 Inhibitors: Targeting Mitochondrial Apoptotic Pathways in Cancer Therapy

(2009) M. H. Kang et al.   CLINICAL CANCER RESEARCH

FOXO Transcription Factors Enforce Cell Cycle Checkpoints and Promote Survival of Hematopoietic Cells after DNA Damage

(2009) H. Lei et al.   MOLECULAR CANCER RESEARCH

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

CDK Inhibitors: Cell Cycle Regulators and Beyond

(2008) Arnaud Besson et al.   DEVELOPMENTAL CELL

Oleanolic acid and related derivatives as medicinally important compounds

(2008) Nighat Sultana et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

PI3K/Akt: getting it right matters

(2008) T F Franke   ONCOGENE

Chemoprevention of Colon Carcinogenesis by Oleanolic Acid and Its Analog in Male F344 Rats and Modulation of COX-2 and Apoptosis in Human Colon HT-29 Cancer Cells

(2008) Naveena B. Janakiram et al.   PHARMACEUTICAL RESEARCH

Ursolic Acid and Oleanolic Acid Suppress Preneoplastic Lesions Induced by 1,2-Dimethylhydrazine in Rat Colon

(2008) Ricardo A. Furtado et al.   TOXICOLOGIC PATHOLOGY

GSK-3β regulates cyclin D1 expression: A new target for chemotherapy

(2007) Fumi Takahashi-Yanaga et al.   CELLULAR SIGNALLING