Perspective: Cooperation of Nanog, NF-κΒ, and CXCR4 in a regulatory network for directed migration of cancer stem cells
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Title
Perspective: Cooperation of Nanog, NF-κΒ, and CXCR4 in a regulatory network for directed migration of cancer stem cells
Authors
Keywords
Cancer stem cell, CXCR4/CXCL12 axis, Nanog, NF-κB, Directed cell migration, Metastasis, Stemness
Journal
TUMOR BIOLOGY
Volume 37, Issue 2, Pages 1559-1565
Publisher
Springer Nature
Online
2015-12-29
DOI
10.1007/s13277-015-4690-6
References
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Related references
Note: Only part of the references are listed.- Cancer stem cells and the tumor microenvironment: interplay in tumor heterogeneity
- (2015) Adriana Albini et al. CONNECTIVE TISSUE RESEARCH
- Su1958 Long Non-Coding RNA Hotair, Enhances Sdf1a-CXCR4- Induced Migration and Invasion in Esophageal Squamous Cell Carcinoma
- (2015) Wenhao Weng et al. GASTROENTEROLOGY
- Cancer stem cells in basic science and in translational oncology: can we translate into clinical application?
- (2015) Axel Schulenburg et al. Journal of Hematology & Oncology
- Integration of actin dynamics and cell adhesion by a three-dimensional, mechanosensitive molecular clutch
- (2015) Lindsay B. Case et al. NATURE CELL BIOLOGY
- Targeting the root of cancer relapse
- (2015) Alexandra Flemming NATURE REVIEWS DRUG DISCOVERY
- Suppression of cancer relapse and metastasis by inhibiting cancer stemness
- (2015) Youzhi Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The pluripotency factor NANOG promotes the formation of squamous cell carcinomas
- (2015) Adelaida R. Palla et al. Scientific Reports
- Hedgehog Signaling in the Maintenance of Cancer Stem Cells
- (2015) Catherine Cochrane et al. Cancers
- The molecular mechanism of HOTAIR in tumorigenesis, metastasis, and drug resistance
- (2014) Xiaolong Zhou et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Bmi1 regulates self-renewal and epithelial to mesenchymal transition in breast cancer cells through Nanog
- (2014) Anurag N Paranjape et al. BMC CANCER
- Bmi-1 regulates the migration and invasion of glioma cells through p16
- (2014) Jun Liang et al. CELL BIOLOGY INTERNATIONAL
- Evolution of the Cancer Stem Cell Model
- (2014) Antonija Kreso et al. Cell Stem Cell
- The role of CXCR4 in highly malignant human gliomas biology: Current knowledge and future directions
- (2014) Filippo Gagliardi et al. GLIA
- Enhanced Chemosensitivity by Targeting Nanog in Head and Neck Squamous Cell Carcinomas
- (2014) Chuan-En Huang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells
- (2014) T. Yi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CXCR4 as a novel predictive biomarker for metastasis and poor prognosis in colorectal cancer
- (2014) Ying Gao et al. TUMOR BIOLOGY
- NF-κB Signaling Pathway Confers Neuroblastoma Cells Migration and Invasion Ability via the Regulation of CXCR4
- (2014) Kun Yang MEDICAL SCIENCE MONITOR
- FAK and Nanog Cross Talk with p53 in Cancer Stem Cells
- (2013) Vita M. Golubovskaya Anti-Cancer Agents in Medicinal Chemistry
- Disrupting the CXCL12/CXCR4 axis disturbs the characteristics of glioblastoma stem-like cells of rat RG2 glioblastoma
- (2013) Chin-Cheng Lee et al. Cancer Cell International
- STAT3 mediates TGF-β1-induced TWIST1 expression and prostate cancer invasion
- (2013) Kyung Hwa Cho et al. CANCER LETTERS
- The symphony of cell movement: how cells orchestrate diverse signals and forces to control migration
- (2013) Carole A Parent et al. CURRENT OPINION IN CELL BIOLOGY
- The metastasis-promoting roles of tumor-associated immune cells
- (2013) Heath A. Smith et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Tumour heterogeneity and cancer cell plasticity
- (2013) Corbin E. Meacham et al. NATURE
- Phosphorylation of Nanog is essential to regulate Bmi1 and promote tumorigenesis
- (2013) X Xie et al. ONCOGENE
- Long Intergenic Noncoding RNA HOTAIR Is Overexpressed and Regulates PTEN Methylation in Laryngeal Squamous Cell Carcinoma
- (2012) Dandan Li et al. AMERICAN JOURNAL OF PATHOLOGY
- Bmi-1 promotes the aggressiveness of glioma via activating the NF-kappaB/MMP-9 signaling pathway
- (2012) Lili Jiang et al. BMC CANCER
- SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial–mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway
- (2012) Xuqi Li et al. CANCER LETTERS
- Multiscale mechanisms of cell migration during development: theory and experiment
- (2012) R. McLennan et al. DEVELOPMENT
- Synergistic induction of cancer cell migration regulated by Gβγ and phosphatidylinositol 3-kinase
- (2012) Eun Kyoung Kim et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- CXCL12/CXCR4 Protein Signaling Axis Induces Sonic Hedgehog Expression in Pancreatic Cancer Cells via Extracellular Regulated Kinase- and Akt Kinase-mediated Activation of Nuclear Factor κB
- (2012) Ajay P. Singh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nanog Increases Focal Adhesion Kinase (FAK) Promoter Activity and Expression and Directly Binds to FAK Protein to Be Phosphorylated
- (2012) Baotran Ho et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nanog and Oct4 overexpression increases motility and transmigration of melanoma cells
- (2012) Aurelie Borrull et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Stem cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-cadherin and FoxJ1 and contributes to adverse clinical outcome in ovarian cancers
- (2012) M K Y Siu et al. ONCOGENE
- Upregulation of CXCR4 is functionally crucial for maintenance of stemness in drug-resistant non-small cell lung cancer cells
- (2012) M-J Jung et al. ONCOGENE
- Cancer stem cells, tumor dormancy, and metastasis
- (2012) Purvi Patel et al. Frontiers in Endocrinology
- Snail1 induces epithelial-to-mesenchymal transition and tumor initiating stem cell characteristics
- (2011) Hien Dang et al. BMC CANCER
- Egfl7 Promotes Tumor Escape from Immunity by Repressing Endothelial Cell Activation
- (2011) S. Delfortrie et al. CANCER RESEARCH
- Tumor Metastasis: Molecular Insights and Evolving Paradigms
- (2011) Scott Valastyan et al. CELL
- The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network
- (2011) M Fareh et al. CELL DEATH AND DIFFERENTIATION
- Targeting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Signaling Network in Cancer Stem Cells
- (2011) A. M. Martelli et al. CURRENT MEDICINAL CHEMISTRY
- Directed cell invasion and migration during metastasis
- (2011) Jose Javier Bravo-Cordero et al. CURRENT OPINION IN CELL BIOLOGY
- Interactions between cancer stem cells and their niche govern metastatic colonization
- (2011) Ilaria Malanchi et al. NATURE
- Cancer stem cells and cancer therapy
- (2011) Sara Soltanian et al. TUMOR BIOLOGY
- Eukaryotic Chemotaxis: A Network of Signaling Pathways Controls Motility, Directional Sensing, and Polarity
- (2010) Kristen F. Swaney et al. Annual Review of Biophysics
- The Canonical NF- B Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
- (2010) M. Liu et al. CANCER RESEARCH
- Nanog, Gli, and p53: a new network of stemness in development and cancer
- (2010) Sebastian Brandner EMBO JOURNAL
- Hedgehog controls neural stem cells through p53-independent regulation of Nanog
- (2010) Agnese Po et al. EMBO JOURNAL
- NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53
- (2010) Marie Zbinden et al. EMBO JOURNAL
- Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice
- (2010) Mitomu Kioi et al. JOURNAL OF CLINICAL INVESTIGATION
- Protein kinase Cɛ mediates Stat3Ser727 phosphorylation, Stat3-regulated gene expression and cell invasion in various human cancer cell lines through integration with MAPK cascade (RAF-1, MEK1/2 and ERK1/2)
- (2010) M H Aziz et al. ONCOGENE
- Frequent Deregulations in the Hedgehog Signaling Network and Cross-Talks with the Epidermal Growth Factor Receptor Pathway Involved in Cancer Progression and Targeted Therapies
- (2010) M. Mimeault et al. PHARMACOLOGICAL REVIEWS
- Nanog Regulates Primordial Germ Cell Migration Through Cxcr4b
- (2010) Ana Virginia Sánchez-Sánchez et al. STEM CELLS
- EMT, the cytoskeleton, and cancer cell invasion
- (2009) Mahmut Yilmaz et al. CANCER AND METASTASIS REVIEWS
- Novel role for epidermal growth factor-like domain 7 in metastasis of human hepatocellular carcinoma
- (2009) Fan Wu et al. HEPATOLOGY
- The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells
- (2009) Li-Bing Song et al. JOURNAL OF CLINICAL INVESTIGATION
- Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells
- (2008) David J. Wong et al. Cell Stem Cell
- IGF-1–Overexpressing Mesenchymal Stem Cells Accelerate Bone Marrow Stem Cell Mobilization via Paracrine Activation of SDF-1α/CXCR4 Signaling to Promote Myocardial Repair
- (2008) Husnain Kh Haider et al. CIRCULATION RESEARCH
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