Blocking autophagy enhanced leukemia cell death induced by recombinant human arginase

Autophagy plays an important role in protecting Pacific oysters from OsHV-1 andVibrio aestuarianusinfections

(2015) Pierrick Moreau et al.   Autophagy

Targeting Hedgehog signaling pathway and autophagy overcomes drug resistance of BCR-ABL-positive chronic myeloid leukemia

(2015) Xian Zeng et al.   Autophagy

A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90

(2015) Christopher NJ Young et al.   Autophagy

Arginine dependence of acute myeloid leukemia blast proliferation: a novel therapeutic target

(2015) F. Mussai et al.   BLOOD

Randomized trial of radiation-free central nervous system prophylaxis comparing intrathecal triple therapy with liposomal cytarabine in acute lymphoblastic leukemia

(2015) R. Bassan et al.   HAEMATOLOGICA

Induction of Heme Oxygenase-1 by Na+-H+Exchanger 1 Protein Plays a Crucial Role in Imatinib-resistant Chronic Myeloid Leukemia Cells

(2015) Dan Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment

(2015) Kazuhiro Tanaka et al.   JOURNAL OF CLINICAL INVESTIGATION

Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells

(2015) Oula Khoury et al.   JOURNAL OF NEURO-ONCOLOGY

The Tyrosine Kinase Inhibitors Imatinib and Dasatinib Reduce Myeloid Suppressor Cells and Release Effector Lymphocyte Responses

(2015) L. Christiansson et al.   MOLECULAR CANCER THERAPEUTICS

Synergistic inhibition of autophagy and neddylation pathways as a novel therapeutic approach for targeting liver cancer

(2015) Ping Chen et al.   Oncotarget

Simultaneous inhibition of deubiquitinating enzymes (DUBs) and autophagy synergistically kills breast cancer cells

(2015) Rachel Isaksson Vogel et al.   Oncotarget

Asparaginase induces apoptosis and cytoprotective autophagy in chronic myeloid leukemia cells

(2015) Ping Song et al.   Oncotarget

Identification of vitamin B1 metabolism as a tumor-specific radiosensitizing pathway using a high-throughput colony formation screen

(2015) Gaganpreet S. Tiwana et al.   Oncotarget

Randomized trial of radiation-free central nervous system prophylaxis comparing intrathecal triple therapy with liposomal cytarabine in acute lymphoblastic leukemia

(2015) R. Bassan et al.   HAEMATOLOGICA

Tyrosine kinase inhibitor Thiotanib targets Bcr-Abl and induces apoptosis and autophagy in human chronic myeloid leukemia cells

(2014) Jiajun Fan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The role of autophagy in the neurotoxicity of cationic PAMAM dendrimers

(2014) Shaofei Wang et al.   BIOMATERIALS

Chloroquine potentiates temozolomide cytotoxicity by inhibiting mitochondrial autophagy in glioma cells

(2014) Yusuke S. Hori et al.   JOURNAL OF NEURO-ONCOLOGY

Asparagine Plays a Critical Role in Regulating Cellular Adaptation to Glutamine Depletion

(2014) Ji Zhang et al.   MOLECULAR CELL

Inhibition of autophagy protects against PAMAM dendrimers-induced hepatotoxicity

(2014) Yubin Li et al.   Nanotoxicology

Metformin Induces Apoptosis and Cell Cycle Arrest Mediated by Oxidative Stress, AMPK and FOXO3a in MCF-7 Breast Cancer Cells

(2014) Eveline A. I. F. Queiroz et al.   PLoS One

Arginine Starvation Impairs Mitochondrial Respiratory Function in ASS1-Deficient Breast Cancer Cells

(2014) F. Qiu et al.   Science Signaling

Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells

(2014) Z Wang et al.   Cell Death & Disease

Involvement of autophagy in recombinant human arginase-induced cell apoptosis and growth inhibition of malignant melanoma cells

(2013) Ziyu Wang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathway

(2013) Gang Wan et al.   Autophagy

Suppression of Autophagy Enhanced Growth Inhibition and Apoptosis of Interferon-β in Human Glioma Cells

(2013) Yubin Li et al.   MOLECULAR NEUROBIOLOGY

Recombinant human arginase induced caspase-dependent apoptosis and autophagy in non-Hodgkin’s lymphoma cells

(2013) X Zeng et al.   Cell Death & Disease

Blocking the interleukin 2 (IL2)-induced systemic autophagic syndrome promotes profound antitumor effects and limits toxicity

(2012) Michael T. Lotze et al.   Autophagy

Impact of genetic polymorphisms on chemotherapy toxicity in childhood acute lymphoblastic leukemia

(2012) Guillermo Gervasini et al.   Frontiers in Genetics

Recombinant human arginase inhibits the in vitro and in vivo proliferation of human melanoma by inducing cell cycle arrest and apoptosis

(2010) Tin-Lun Lam et al.   Pigment Cell & Melanoma Research