Sodium chloride, SGK1, and Th17 activation

IL-17 and related cytokines involved in the pathology and immunotherapy of multiple sclerosis: Current and future developments

(2014) Dirk W. Luchtman et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Spironolactone Decreases DOCA–Salt–Induced Organ Damage by Blocking the Activation of T Helper 17 and the Downregulation of Regulatory T Lymphocytes

(2014) Cristián A. Amador et al.   HYPERTENSION

SGK1: master and commander of the fate of helper T cells

(2014) Matthew Norton et al.   NATURE IMMUNOLOGY

The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex

(2014) Emily B Heikamp et al.   NATURE IMMUNOLOGY

De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells

(2014) Luciana Berod et al.   NATURE MEDICINE

Global Sodium Consumption and Death from Cardiovascular Causes

(2014) Dariush Mozaffarian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Liver X Receptor a Inhibits Osteosarcoma Cell Proliferation through Up-Regulation of FoxO1

(2013) Yue-wen Chang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

IL-17A Induces Pro-Inflammatory Cytokines Production in Macrophages via MAPKinases, NF-κB and AP-1

(2013) Jian Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Therapeutic potential of serum and glucocorticoid inducible kinase inhibition

(2013) Florian Lang et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Deficiency of the Interleukin 17/23 Axis Accelerates Renal Injury in Mice With Deoxycorticosterone Acetate+Angiotensin II–Induced Hypertension

(2013) Christian F. Krebs et al.   HYPERTENSION

Immune cells control skin lymphatic electrolyte homeostasis and blood pressure

(2013) Helge Wiig et al.   JOURNAL OF CLINICAL INVESTIGATION

Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1

(2013) Chuan Wu et al.   NATURE

Transcriptional control of regulatory T cell development and function

(2013) Chong T. Luo et al.   TRENDS IN IMMUNOLOGY

Serum-Glucocorticoid Regulated Kinase 1 Regulates Alternatively Activated Macrophage Polarization Contributing to Angiotensin II–Induced Inflammation and Cardiac Fibrosis

(2012) Min Yang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Sgk1 sensitivity of Na+/H+ exchanger activity and cardiac remodeling following pressure overload

(2012) Jakob Voelkl et al.   BASIC RESEARCH IN CARDIOLOGY

The IL-17A/IL-17RA Axis Plays a Proatherogenic Role via the Regulation of Aortic Myeloid Cell Recruitment

(2012) Matthew J. Butcher et al.   CIRCULATION RESEARCH

Interferon-γ Signaling Inhibition Ameliorates Angiotensin II–Induced Cardiac Damage

(2012) Lajos Markó et al.   HYPERTENSION

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β

(2012) Christina E. Zielinski et al.   NATURE

Functional interactions between the gut microbiota and host metabolism

(2012) Valentina Tremaroli et al.   NATURE

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

(2012) Lam C Tsoi et al.   NATURE GENETICS

Induction and molecular signature of pathogenic TH17 cells

(2012) Youjin Lee et al.   NATURE IMMUNOLOGY

FoxO transcription factors; Regulation by AKT and 14-3-3 proteins

(2011) Guri Tzivion et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

(2011) Eric V. Dang et al.   CELL

Stimulation of Ca2+-channel Orai1/STIM1 by serum- and glucocorticoid-inducible kinase 1 (SGK1)

(2011) Anja Eylenstein et al.   FASEB JOURNAL

Twin studies in autoimmune disease: Genetics, gender and environment

(2011) Dimitrios P. Bogdanos et al.   JOURNAL OF AUTOIMMUNITY

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells

(2011) Lewis Z. Shi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic variants in serum and glucocortocoid regulated kinase 1, a regulator of the epithelial sodium channel, are associated with ischaemic stroke

(2011) Jonas Dahlberg et al.   JOURNAL OF HYPERTENSION

Control of TH17 cells occurs in the small intestine

(2011) Enric Esplugues et al.   NATURE

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

(2010) Kamran Ghoreschi et al.   NATURE

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Attenuated atherosclerosis upon IL-17R signaling disruption in LDLr deficient mice

(2009) T. van Es et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Interleukin 17 Promotes Angiotensin II–Induced Hypertension and Vascular Dysfunction

(2009) Meena S. Madhur et al.   HYPERTENSION

Tonicity-dependent induction of Sgk1 expression has a potential role in dehydration-induced natriuresis in rodents

(2009) Songcang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Time Trends in Epidemiology and Characteristics of Psoriatic Arthritis Over 3 Decades: A Population-based Study

(2009) F. C. WILSON et al.   JOURNAL OF RHEUMATOLOGY

Serum- and Glucocorticoid-Inducible Kinase 1 (SGK1) Regulates Adipocyte Differentiation via Forkhead Box O1

(2009) Natalia Di Pietro et al.   MOLECULAR ENDOCRINOLOGY

Psoriasis

(2009) Frank O. Nestle et al.   NEW ENGLAND JOURNAL OF MEDICINE

Brx Shines a Light on the Route from Hyperosmolarity to NFAT5

(2009) J. Aramburu et al.   Science Signaling

Role of maternal glucocorticoid inducible kinase SGK1 in fetal programming of blood pressure in response to prenatal diet

(2008) Rexhep Rexhepaj et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

(2008) Ivaylo I. Ivanov et al.   Cell Host & Microbe

Association of SGK1 Gene Polymorphisms with Type 2 Diabetes

(2008) Matthias Schwab et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

SGK1 Phosphorylation of IκB Kinase α and p300 Up-regulates NF-κB Activity and IncreasesN-Methyl-D-aspartate Receptor NR2A and NR2B Expression

(2008) Derek J. C. Tai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wnt Signaling Inhibits Forkhead Box O3a-induced Transcription and Apoptosis through Up-regulation of Serum- and Glucocorticoid-inducible Kinase 1

(2008) Manuel Dehner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22

(2008) Hiroaki Takatori et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Aldosterone-Stimulated SGK1 Activity Mediates Profibrotic Signaling in the Mesangium

(2008) Y. Terada et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY