Hesperidin attenuates learning and memory deficits in APP/PS1 mice through activation of Akt/Nrf2 signaling and inhibition of RAGE/NF-κB signaling

Mitochondrial Alterations, Oxidative Stress and Neuroinflammation in Alzheimer's Disease

(2017) M. Verri et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Hesperidin ameliorates behavioral impairments and neuropathology of transgenic APP/PS1 mice

(2015) Chaoyun Li et al.   BEHAVIOURAL BRAIN RESEARCH

Increased Alzheimer's disease–like pathology in the APP/ PS1ΔE9 mouse model lacking Nrf2 through modulation of autophagy

(2015) Gururaj Joshi et al.   NEUROBIOLOGY OF AGING

Neuroprotective Effect of Hesperidin on Aluminium Chloride Induced Alzheimer’s Disease in Wistar Rats

(2015) Arokiasamy Justin Thenmozhi et al.   NEUROCHEMICAL RESEARCH

Ginseng improves cognitive deficit via the RAGE/NF-κB pathway in advanced glycation end product-induced rats

(2015) Xiaobin Tan et al.   Journal of Ginseng Research

Altered behavioral development in Nrf2 knockout mice following early postnatal exposure to valproic acid

(2014) Melody A. Furnari et al.   BRAIN RESEARCH BULLETIN

Hesperidin Alleviates Cognitive Impairment, Mitochondrial Dysfunction and Oxidative Stress in a Mouse Model of Alzheimer’s Disease

(2014) Dongmei Wang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Neuropharmacological properties and pharmacokinetics of the citrus flavonoids hesperidin and hesperetin — A mini-review

(2014) Ali Roohbakhsh et al.   LIFE SCIENCES

Trientine Reduces BACE1 Activity and Mitigates Amyloidosis via the AGE/RAGE/NF-κB Pathway in a Transgenic Mouse Model of Alzheimer's Disease

(2013) Chun-Yan Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease

(2013) Susan A. Farr et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neuroinflammation, Oxidative Stress and the Pathogenesis of Alzheimers Disease

(2012) Paula Agostinho et al.   CURRENT PHARMACEUTICAL DESIGN

Neuroprotective Effects of Citrus Flavonoids

(2012) Sam-Long Hwang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Critical role of intraneuronal Aβ in Alzheimer's disease: Technical challenges in studying intracellular Aβ

(2012) Gunnar K. Gouras et al.   LIFE SCIENCES

Cytoprotective effects of hesperetin and hesperidin against amyloid β-induced impairment of glucose transport through downregulation of neuronal autophagy

(2012) Shang-Ming Huang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Quercetin protects against the Aβ25–35-induced amnesic injury: Involvement of inactivation of RAGE-mediated pathway and conservation of the NVU

(2012) Rui Liu et al.   NEUROPHARMACOLOGY

Tetrandrine attenuates spatial memory impairment and hippocampal neuroinflammation via inhibiting NF-κB activation in a rat model of Alzheimer's disease induced by amyloid-β(1–42)

(2011) Fu-Qian He et al.   BRAIN RESEARCH

Hesperidin ameliorates functional and histological outcome and reduces neuroinflammation in experimental stroke

(2011) Syed Shadab Raza et al.   BRAIN RESEARCH

Effects of Antioxidant Polyphenols on TNF-Alpha-Related Diseases

(2011) Kiichiro Kawaguchi et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

SCF/ -TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner

(2011) P. Rada et al.   MOLECULAR AND CELLULAR BIOLOGY

Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation

(2011) Brooks M. Hybertson et al.   MOLECULAR ASPECTS OF MEDICINE

RAGE-dependent signaling in microglia contributes to neuroinflammation, Aβ accumulation, and impaired learning/memory in a mouse model of Alzheimer’s disease

(2009) Fang Fang et al.   FASEB JOURNAL

Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease

(2009) K. Kanninen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippocampal RAGE immunoreactivity in early and advanced Alzheimer's disease

(2008) Miles C. Miller et al.   BRAIN RESEARCH

Possible Involvement of Advanced Glycation End-Products (AGEs) in the Pathogenesis of Alzheimers Disease

(2008) Masayoshi Takeuchi et al.   CURRENT PHARMACEUTICAL DESIGN

Amyloid β-Protein Toxicity and the Pathogenesis of Alzheimer Disease

(2008) Bruce A. Yankner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear factor erythroid 2-related factor 2 protects against beta amyloid

(2008) Katja Kanninen et al.   MOLECULAR AND CELLULAR NEUROSCIENCE