SCF/ -TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner

The Transcription Factor Nrf2 Is a Therapeutic Target against Brain Inflammation

(2014) N. G. Innamorato et al.   JOURNAL OF IMMUNOLOGY

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF -TRCP

(2010) B. Zhao et al.   GENES & DEVELOPMENT

The rise of antioxidant signaling—The evolution and hormetic actions of Nrf2

(2010) Jonathan Maher et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nrf2 Enhances Cell Proliferation and Resistance to Anticancer Drugs in Human Lung Cancer

(2009) S. Homma et al.   CLINICAL CANCER RESEARCH

Role of microglial redox balance in modulation of neuroinflammation

(2009) Nadia G Innamorato et al.   CURRENT OPINION IN NEUROLOGY

The transcription factor Nrf2 as a new therapeutic target in Parkinson's disease

(2009) Antonio Cuadrado et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Nrf2 promotes neuronal cell differentiation

(2009) Fei Zhao et al.   FREE RADICAL BIOLOGY AND MEDICINE

 -TrCP-Mediated Ubiquitination and Degradation of PHLPP1 Are Negatively Regulated by Akt

(2009) X. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

Phosphorylation of Nrf2 at Multiple Sites by MAP Kinases Has a Limited Contribution in Modulating the Nrf2-Dependent Antioxidant Response

(2009) Zheng Sun et al.   PLoS One

NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

(2009) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Nrf2/ARE Pathway as a Potential Therapeutic Target in Neurodegenerative Disease

(2008) Marcus J. Calkins et al.   ANTIOXIDANTS & REDOX SIGNALING

GSK-3β Targets Cdc25A for Ubiquitin-Mediated Proteolysis, and GSK-3β Inactivation Correlates with Cdc25A Overproduction in Human Cancers

(2008) Tiebang Kang et al.   CANCER CELL

Novel insights into FGD3, a putative GEF for Cdc42, that undergoes SCFFWD1/β-TrCP-mediated proteasomal degradation analogous to that of its homologue FGD1 but regulates cell morphology and motility differently from FGD1

(2008) Makio Hayakawa et al.   GENES TO CELLS

Phosphorylation of Nrf2 in the transcription activation domain by casein kinase 2 (CK2) is critical for the nuclear translocation and transcription activation function of Nrf2 in IMR-32 neuroblastoma cells

(2008) Patrick L. Apopa et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

UV-induced degradation of securin is mediated by SKP1-CUL1- TrCP E3 ubiquitin ligase

(2008) M. C. Limon-Mortes et al.   JOURNAL OF CELL SCIENCE

GSK-3β down-regulates the transcription factor Nrf2 after oxidant damage: relevance to exposure of neuronal cells to oxidative stress

(2008) Ana I. Rojo et al.   JOURNAL OF NEUROCHEMISTRY

Polyubiquitination of Prolactin Receptor Stimulates Its Internalization, Postinternalization Sorting, and Degradation via the Lysosomal Pathway

(2008) B. Varghese et al.   MOLECULAR AND CELLULAR BIOLOGY

Functional interference between glycogen synthase kinase-3 beta and the transcription factor Nrf2 in protection against kainate-induced hippocampal celldeath

(2008) Ana I. Rojo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

(2008) T. Shibata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA