Trientine Reduces BACE1 Activity and Mitigates Amyloidosis via the AGE/RAGE/NF-κB Pathway in a Transgenic Mouse Model of Alzheimer's Disease
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Title
Trientine Reduces BACE1 Activity and Mitigates Amyloidosis via the AGE/RAGE/NF-κB Pathway in a Transgenic Mouse Model of Alzheimer's Disease
Authors
Keywords
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Journal
ANTIOXIDANTS & REDOX SIGNALING
Volume 19, Issue 17, Pages 2024-2039
Publisher
Mary Ann Liebert Inc
Online
2013-04-01
DOI
10.1089/ars.2012.5158
References
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- (2011) Garth J.S. Cooper DRUGS
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- (2009) G. J. S. Cooper et al. DIABETOLOGIA
- The Metal Chelators, Trientine and Citrate, Inhibit the Development of Cardiac Pathology in the Zucker Diabetic Rat
- (2009) John W. Baynes et al. Experimental Diabetes Research
- RAGE regulates BACE1 and Aβ generation via NFAT1 activation in Alzheimer’s disease animal model
- (2009) H. J. Cho et al. FASEB JOURNAL
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- (2009) R. Vassar et al. JOURNAL OF NEUROSCIENCE
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- (2008) Ganesh M Shankar et al. NATURE MEDICINE
- Characterization and antitumor activity of triethylene tetramine, a novel telomerase inhibitor
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