Hesperidin Alleviates Cognitive Impairment, Mitochondrial Dysfunction and Oxidative Stress in a Mouse Model of Alzheimer’s Disease

Hesperidin pre-treatment attenuates NO-mediated cerebral ischemic reperfusion injury and memory dysfunction

(2014) Vaibhav Gaur et al.   Pharmacological Reports

Naringin Enhances CaMKII Activity and Improves Long-Term Memory in a Mouse Model of Alzheimer’s Disease

(2013) Dong-Mei Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protective Effects of Hesperidin Against Amyloid-β (Aβ) Induced Neurotoxicity Through the Voltage Dependent Anion Channel 1 (VDAC1)-Mediated Mitochondrial Apoptotic Pathway in PC12 Cells

(2013) Dong-Mei Wang et al.   NEUROCHEMICAL RESEARCH

Mitochondria, oxidative stress and neurodegeneration

(2012) Antonio Federico et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Mitochondrial Dysfunction—A Pharmacological Target in Alzheimer's Disease

(2012) Gunter P. Eckert et al.   MOLECULAR NEUROBIOLOGY

Cytoprotective effects of hesperetin and hesperidin against amyloid β-induced impairment of glucose transport through downregulation of neuronal autophagy

(2012) Shang-Ming Huang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Potential neuroprotective effects of hesperidin on 3-nitropropionic acid-induced neurotoxicity in rats

(2012) Esther T. Menze et al.   NEUROTOXICOLOGY

Long-term naringin consumption reverses a glucose uptake defect and improves cognitive deficits in a mouse model of Alzheimer's disease

(2012) Dongmei Wang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Flavonoids as antioxidants in plants: Location and functional significance

(2012) Giovanni Agati et al.   PLANT SCIENCE

Mitochondria-Specific Accumulation of Amyloid β Induces Mitochondrial Dysfunction Leading to Apoptotic Cell Death

(2012) Moon-Yong Cha et al.   PLoS One

Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: Implications to mitochondria-targeted antioxidant therapeutics

(2011) P. Hemachandra Reddy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hesperidin ameliorates functional and histological outcome and reduces neuroinflammation in experimental stroke

(2011) Syed Shadab Raza et al.   BRAIN RESEARCH

Evaluating the radioprotective effect of hesperidin in the liver of Swiss albino mice

(2011) Kalyanasundaram Banumathy Kalpana et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Glycogen synthase kinase-3 inhibition reduces ischemic cerebral damage, restores impaired mitochondrial biogenesis and prevents ROS production

(2011) Alessandra Valerio et al.   JOURNAL OF NEUROCHEMISTRY

Evaluation of respiratory chain activity in lymphocytes of patients with Alzheimer disease

(2011) Pollyana Feldhaus et al.   METABOLIC BRAIN DISEASE

Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse

(2011) Ayumi Takamura et al.   Molecular Neurodegeneration

Activation of glycogen synthase kinase-3 beta mediates β-amyloid induced neuritic damage in Alzheimer's disease

(2011) B. DaRocha-Souto et al.   NEUROBIOLOGY OF DISEASE

Chronic Intraperitoneal and Oral Treatments with Hesperidin Induce Central Nervous System Effects in Mice

(2011) Cristina Wasowski et al.   PHYTOTHERAPY RESEARCH

The presence of sodium dodecyl sulphate-stable Aβ dimers is strongly associated with Alzheimer-type dementia

(2010) Jessica M. Mc Donald et al.   BRAIN

Effect of flavonoids on the Aβ(25-35)-phospholipid bilayers interaction

(2010) Annamaria Tedeschi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Hesperetin protects testicular toxicity of doxorubicin in rat: Role of NFκB, p38 and caspase-3

(2010) P.P. Trivedi et al.   FOOD AND CHEMICAL TOXICOLOGY

A New Class of Molecular Targeted Radioprotectors: GSK-3β Inhibitors

(2010) Dinesh K. Thotala et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Reduction of β-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease

(2010) Daniel Paris et al.   Journal of Neuroinflammation

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

(2010) H. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bioactive phenolics and antioxidant propensity of flavedo extracts of Mauritian citrus fruits: Potential prophylactic ingredients for functional foods application

(2010) Deena Ramful et al.   TOXICOLOGY

Spatial navigation testing discriminates two types of amnestic mild cognitive impairment

(2009) Jan Laczó et al.   BEHAVIOURAL BRAIN RESEARCH

Protective effect of hesperidin and naringin against 3-nitropropionic acid induced Huntington's like symptoms in rats: Possible role of nitric oxide

(2009) Puneet Kumar et al.   BEHAVIOURAL BRAIN RESEARCH

Aβ Oligomers and Fibrillar Aggregates Induce Different Apoptotic Pathways in LAN5 Neuroblastoma Cell Cultures

(2009) Pasquale Picone et al.   BIOPHYSICAL JOURNAL

Oral apolipoprotein A-I mimetic peptide improves cognitive function and reduces amyloid burden in a mouse model of Alzheimer's disease

(2009) Shaila P. Handattu et al.   NEUROBIOLOGY OF DISEASE

Involvment of Cytosolic and Mitochondrial GSK-3β in Mitochondrial Dysfunction and Neuronal Cell Death of MPTP/MPP+-Treated Neurons

(2009) Agnès Petit-Paitel et al.   PLoS One

Hesperidin attenuates benzo[α] pyrene-induced testicular toxicity in rats via regulation of oxidant/antioxidant balance

(2009) HMM Arafa et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Neuroprotective effects of chronic hesperetin administration in mice

(2008) Eun Jeong Choi et al.   ARCHIVES OF PHARMACAL RESEARCH

GSK-3β inhibition and prevention of mitochondrial apoptosis inducing factor release are not involved in the antioxidant properties of SB-415286

(2008) Marc Yeste-Velasco et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Antioxidative effects of hesperetin against 7,12-dimethylbenz(a)anthracene-induced oxidative stress in mice

(2008) Eun Jeong Choi   LIFE SCIENCES

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice

(2008) S. Hauptmann et al.   NEUROBIOLOGY OF AGING

The release of calcium from the endoplasmic reticulum induced by amyloid-beta and prion peptides activates the mitochondrial apoptotic pathway

(2008) Elisabete Ferreiro et al.   NEUROBIOLOGY OF DISEASE

Soluble Beta-Amyloid Leads to Mitochondrial Defects in Amyloid Precursor Protein and Tau Transgenic Mice

(2008) Anne Eckert et al.   Neurodegenerative Diseases

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

(2008) P. Hemachandra Reddy et al.   TRENDS IN MOLECULAR MEDICINE

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL