Salidroside Attenuates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via AMPK-Dependent TXNIP/NLRP3 Pathway

Salidroside Modulates Insulin Signaling in a Rat Model of Nonalcoholic Steatohepatitis

(2017) Hongshan Li et al.   Evidence-based Complementary and Alternative Medicine

CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation

(2017) Tiantian Tang et al.   Nature Communications

A novel mechanism of action for salidroside to alleviate diabetic albuminuria: effects on albumin transcytosis across glomerular endothelial cells

(2016) Dan Wu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Induction of autophagy by salidroside through the AMPK-mTOR pathway protects vascular endothelial cells from oxidative stress-induced apoptosis

(2016) Xiang-Tao Zheng et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Salidroside protects against kainic acid-induced status epilepticus via suppressing oxidative stress

(2016) Pei-Pei Si et al.   NEUROSCIENCE LETTERS

Salidroside alleviates oxidative stress in the liver with non- alcoholic steatohepatitis in rats

(2016) Ze-ran Yang et al.   BMC Pharmacology & Toxicology

Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?

(2015) Justine M. Abais et al.   ANTIOXIDANTS & REDOX SIGNALING

Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3β pathway

(2015) Tao Zheng et al.   BRITISH JOURNAL OF PHARMACOLOGY

Salidroside improves endothelial function and alleviates atherosclerosis by activating a mitochondria-related AMPK/PI3K/Akt/eNOS pathway

(2015) Sha-Sha Xing et al.   VASCULAR PHARMACOLOGY

Salidroside inhibits oxygen glucose deprivation (OGD)/re-oxygenation-induced H9c2 cell necrosis through activating of Akt–Nrf2 signaling

(2014) Koulong Zheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Resveratrol ameliorates hepatic metaflammation and inhibits NLRP3 inflammasome activation

(2014) Soo Jin Yang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes

(2014) Rachel J. Perry et al.   NATURE

Salidroside Stimulates Mitochondrial Biogenesis and Protects against H2O2-Induced Endothelial Dysfunction

(2014) Shasha Xing et al.   Oxidative Medicine and Cellular Longevity

High glucose-induced mitochondrial respiration and reactive oxygen species in mouse cerebral pericytes is reversed by pharmacological inhibition of mitochondrial carbonic anhydrases: Implications for cerebral microvascular disease in diabetes

(2013) Gul N. Shah et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Deletion of thioredoxin-interacting protein preserves retinal neuronal function by preventing inflammation and vascular injury

(2013) M F El-Azab et al.   BRITISH JOURNAL OF PHARMACOLOGY

Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet

(2013) Islam N. Mohamed et al.   DIABETOLOGIA

Non-alcoholic fatty liver disease as an independent manifestation of the metabolic syndrome: Results of a US national survey in three ethnic groups

(2013) Mark M Smits et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

From NAFLD to NASH to cirrhosis—new insights into disease mechanisms

(2013) Alexander Wree et al.   Nature Reviews Gastroenterology & Hepatology

Caspase-1 as a Central Regulator of High Fat Diet-Induced Non-Alcoholic Steatohepatitis

(2013) Laura J. Dixon et al.   PLoS One

The Inflammasome Puts Obesity in the Danger Zone

(2012) Rinke Stienstra et al.   Cell Metabolism

Is Predisposition to NAFLD and Obesity Communicable?

(2012) Matam Vijay-Kumar et al.   Cell Metabolism

Antidiabetic Effects of Pterosin A, a Small-Molecular-Weight Natural Product, on Diabetic Mouse Models

(2012) F.-L. Hsu et al.   DIABETES

Salidroside Decreases Atherosclerotic Plaque Formation in Low-Density Lipoprotein Receptor-Deficient Mice

(2012) Bu-Chun Zhang et al.   Evidence-based Complementary and Alternative Medicine

Rhodiola crenulata root ameliorates derangements of glucose and lipid metabolism in a rat model of the metabolic syndrome and type 2 diabetes

(2012) Jianwei Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes

(2012) Carolina E. Hagberg et al.   NATURE

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

(2012) Jorge Henao-Mejia et al.   NATURE

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

(2011) Yu Li et al.   Cell Metabolism

Inflammation Is Necessary for Long-Term but Not Short-Term High-Fat Diet-Induced Insulin Resistance

(2011) Y. S. Lee et al.   DIABETES

Hyperglycemia Activates Caspase-1 and TXNIP-Mediated IL-1  Transcription in Human Adipose Tissue

(2011) T. B. Koenen et al.   DIABETES

Antidiabetic effect of total saponins from Entada phaseoloides (L.) Merr. in type 2 diabetic rats

(2011) Tao Zheng et al.   JOURNAL OF ETHNOPHARMACOLOGY

Neuroprotection against cobalt chloride-induced cell apoptosis of primary cultured cortical neurons by salidroside

(2011) Shuqiang Zhang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Inhibitory effects of garcinol and pterostilbene on cell proliferation and adipogenesis in 3T3-L1 cells

(2011) Chin-Lin Hsu et al.   Food & Function

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Salidroside Attenuates Apoptosis in Ischemic Cardiomyocytes: a Mechanism Through a Mitochondria-Dependent Pathway

(2010) Han Zhong et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Salidroside attenuates hypoxia-induced abnormal processing of amyloid precursor protein by decreasing BACE1 expression in SH-SY5Y cells

(2010) Qing-Yun Li et al.   NEUROSCIENCE LETTERS

Novel Insights into the Pathophysiology of Nonalcoholic Fatty Liver Disease

(2010) Ariel Feldstein   SEMINARS IN LIVER DISEASE

Inhibition of TXNIP expression in vivo blocks early pathologies of diabetic retinopathy

(2010) L Perrone et al.   Cell Death & Disease

Imatinib Mesylate Reduces Endoplasmic Reticulum Stress and Induces Remission of Diabetes in db/db Mice

(2009) M. S. Han et al.   DIABETES

Glucose-stimulated Expression of Txnip Is Mediated by Carbohydrate Response Element-binding Protein, p300, and Histone H4 Acetylation in Pancreatic Beta Cells

(2009) Hyunjoo Cha-Molstad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Cirrhosis and liver failure in nonalcoholic fatty liver disease: Molehill or mountain?

(2008) Michael Charlton   HEPATOLOGY

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY