Cellular Accumulation and Toxic Effects of Bile Acids in Cyclosporine A-Treated HepaRG Hepatocytes

Comparative Localization and Functional Activity of the Main Hepatobiliary Transporters in HepaRG Cells and Primary Human Hepatocytes

(2015) Pamela Bachour-El Azzi et al.   TOXICOLOGICAL SCIENCES

Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis

(2015) Benjamin L. Woolbright et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Potency of Individual Bile Acids to Regulate Bile Acid Synthesis and Transport Genes in Primary Human Hepatocyte Cultures

(2014) Jie Liu et al.   TOXICOLOGICAL SCIENCES

Different Dose-Dependent Mechanisms Are Involved in Early Cyclosporine A-Induced Cholestatic Effects in HepaRG Cells

(2014) Ahmad Sharanek et al.   TOXICOLOGICAL SCIENCES

Efficacy and Safety of the Farnesoid X Receptor Agonist Obeticholic Acid in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease

(2013) Sunder Mudaliar et al.   GASTROENTEROLOGY

Cytochromes P450: Roles in Diseases

(2013) Irina A. Pikuleva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Multifactorial Approach to Hepatobiliary Transporter Assessment Enables Improved Therapeutic Compound Development

(2013) Ryan E. Morgan et al.   TOXICOLOGICAL SCIENCES

Drug-Induced Cholestasis

(2012) Einar S. Bjornsson et al.   Clinics in Liver Disease

Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells

(2012) Sébastien Anthérieu et al.   HEPATOLOGY

Bile acid profiling in human biological samples: Comparison of extraction procedures and application to normal and cholestatic patients

(2012) Lydie Humbert et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Endogenous bile acid disposition in rat and human sandwich-cultured hepatocytes

(2012) Tracy L. Marion et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells

(2009) S. Antherieu et al.   DRUG METABOLISM AND DISPOSITION

New molecular insights into the mechanisms of cholestasis

(2009) Martin Wagner et al.   JOURNAL OF HEPATOLOGY

Bile acid transporters

(2009) Paul A. Dawson et al.   JOURNAL OF LIPID RESEARCH

Bile acids: regulation of synthesis

(2009) John Y. L. Chiang   JOURNAL OF LIPID RESEARCH

Bile Acid Sulfation: A Pathway of Bile Acid Elimination and Detoxification

(2009) Yazen Alnouti   TOXICOLOGICAL SCIENCES

Biochemical mechanisms in drug-induced liver injury: Certainties and doubts

(2009) Ignazio Grattagliano et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Long-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity Studies

(2008) R. Josse et al.   DRUG METABOLISM AND DISPOSITION

Lithocholic acid as a biomarker of intrahepatic cholestasis of pregnancy during ursodeoxycholic acid treatment

(2008) S. E Lucangioli et al.   ANNALS OF CLINICAL BIOCHEMISTRY