Different Dose-Dependent Mechanisms Are Involved in Early Cyclosporine A-Induced Cholestatic Effects in HepaRG Cells

4-Phenylbutyrate Inhibits Tunicamycin-Induced Acute Kidney Injury via CHOP/GADD153 Repression

(2014) Rachel E. Carlisle et al.   PLoS One

Early Identification of Clinically Relevant Drug Interactions With the Human Bile Salt Export Pump (BSEP/ABCB11)

(2013) Jenny M. Pedersen et al.   TOXICOLOGICAL SCIENCES

Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells

(2012) Sébastien Anthérieu et al.   HEPATOLOGY

Bile acid profiling in human biological samples: Comparison of extraction procedures and application to normal and cholestatic patients

(2012) Lydie Humbert et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Endogenous bile acid disposition in rat and human sandwich-cultured hepatocytes

(2012) Tracy L. Marion et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Optimization of the HepaRG cell model for drug metabolism and toxicity studies

(2012) Sébastien Anthérieu et al.   TOXICOLOGY IN VITRO

Heterogeneous accumulation of fluorescent bile acids in primary rat hepatocytes does not correlate with their homogenous expression of ntcp

(2011) John W. Murray et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Quantitative proteomic analysis of cyclosporine-induced toxicity in a human kidney cell line and comparison with tacrolimus

(2011) F. Lamoureux et al.   Journal of Proteomics

A pharmacologically-based array to identify targets of cyclosporine A-induced toxicity in cultured renal proximal tubule cells

(2011) Eduard Sarró et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The PXR is a drug target for chronic inflammatory liver disease

(2010) Karen Wallace et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Expression of ABCG2 (BCRP) Is Regulated by Nrf2 in Cancer Cells That Confers Side Population and Chemoresistance Phenotype

(2010) Anju Singh et al.   MOLECULAR CANCER THERAPEUTICS

Proteomics Investigations of Drug-Induced Hepatotoxicity in HepG2 Cells

(2010) Anke Van Summeren et al.   TOXICOLOGICAL SCIENCES

The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response

(2009) Sana Basseri et al.   JOURNAL OF LIPID RESEARCH

Mechanisms of Cholestasis

(2008) Gernot Zollner et al.   Clinics in Liver Disease