Bile acid transporters

Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin-proteasomal degradation

(2009) J. Miao et al.   GENES & DEVELOPMENT

Mutation screening of apical sodium-dependent bile acid transporter (SLC10A2): novel haplotype block including six newly identified variants linked to reduced expression

(2009) Olga Renner et al.   HUMAN GENETICS

Activity of the Bile Salt Export Pump (ABCB11) Is Critically Dependent on Canalicular Membrane Cholesterol Content

(2009) Coen C. Paulusma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bile acids as regulatory molecules

(2009) Phillip B. Hylemon et al.   JOURNAL OF LIPID RESEARCH

Bile acids: regulation of synthesis

(2009) John Y. L. Chiang   JOURNAL OF LIPID RESEARCH

Measurement of serum 7α-hydroxy-4-cholesten-3-one (or 7αC4), a surrogate test for bile acid malabsorption in health, ileal disease and irritable bowel syndrome using liquid chromatography-tandem mass spectrometry

(2009) m. camilleri et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

(2009) Philippe Lefebvre et al.   PHYSIOLOGICAL REVIEWS

Hepatocyte nuclear factor-4α is a central transactivator of the mouse Ntcp gene

(2008) Andreas Geier et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

β-Klotho and FGF-15/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes

(2008) Jyoti Sinha et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Ostα-Ostβ is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver

(2008) Nazzareno Ballatori et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Bile Acids: Chemistry, Pathochemistry, Biology, Pathobiology, and Therapeutics

(2008) A. F. Hofmann et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Diminished Expression of Apical Sodium-Dependent Bile Acid Transporter in Gallstone Disease Is Independent of Ileal Inflammation

(2008) Arthur Holzer et al.   DIGESTION

Cholesterol Feeding Prevents Hepatic Accumulation of Bile Acids in Cholic Acid-Fed Farnesoid X Receptor (FXR)-Null Mice: FXR-Independent Suppression of Intestinal Bile Acid Absorption

(2008) M. Miyata et al.   DRUG METABOLISM AND DISPOSITION

Regulation of Drug Transporter Expression in Human Hepatocytes Exposed to the Proinflammatory Cytokines Tumor Necrosis Factor-  or Interleukin-6

(2008) M. L. Vee et al.   DRUG METABOLISM AND DISPOSITION

Exploring possible mechanisms for primary bile acid malabsorption: evidence for different regulation of ileal bile acid transporter transcripts in chronic diarrhoea

(2008) Sara Balesaria et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

GATA4 Is Essential for Jejunal Function in Mice

(2008) Michele A. Battle et al.   GASTROENTEROLOGY

Severe Bile Salt Export Pump Deficiency: 82 Different ABCB11 Mutations in 109 Families

(2008) Sandra S. Strautnieks et al.   GASTROENTEROLOGY

ATP8B1 Deficiency Disrupts the Bile Canalicular Membrane Bilayer Structure in Hepatocytes, But FXR Expression and Activity Are Maintained

(2008) Shi–Ying Cai et al.   GASTROENTEROLOGY

Contribution of variant alleles of ABCB11 to susceptibility to intrahepatic cholestasis of pregnancy

(2008) P H Dixon et al.   GUT

Missense mutations and single nucleotide polymorphisms in ABCB11 impair bile salt export pump processing and function or disrupt pre-messenger RNA splicing

(2008) Jane A. Byrne et al.   HEPATOLOGY

Low retinol levels differentially modulate bile salt-induced expression of human and mouse hepatic bile salt transporters

(2008) Martijn O. Hoeke et al.   HEPATOLOGY

High expression of the bile salt-homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis

(2008) Frank G. Schaap et al.   HEPATOLOGY

Reduced ileal expression of OSTα-OSTβ in non-obese gallstone disease

(2008) Olga Renner et al.   JOURNAL OF LIPID RESEARCH

Liver Receptor Homolog-1 Regulates Bile Acid Homeostasis but Is Not Essential for Feedback Regulation of Bile Acid Synthesis

(2008) Youn-Kyoung Lee et al.   MOLECULAR ENDOCRINOLOGY

Analysis of DNA Methylation and Histone Modification Profiles of Liver-Specific Transporters

(2008) S. Imai et al.   MOLECULAR PHARMACOLOGY

Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress

(2008) Irina M Bochkis et al.   NATURE MEDICINE

Targeting bile-acid signalling for metabolic diseases

(2008) Charles Thomas et al.   NATURE REVIEWS DRUG DISCOVERY

Deletion of the ileal basolateral bile acid transporter identifies the cellular sentinels that regulate the bile acid pool

(2008) Roger A. Davis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The organic solute transporter  - , Ost -Ost , is essential for intestinal bile acid transport and homeostasis

(2008) A. Rao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of ileal bile acid transporter (ASBT) activity by depletion of plasma membrane cholesterol: association with lipid rafts

(2007) Fadi Annaba et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis

(2007) S Teng et al.   BRITISH JOURNAL OF PHARMACOLOGY

The use of High Performance Thin-Layer Chromatography to determine the role of membrane lipid composition in bile salt-induced kidney cell damage

(2007) Winston A. Morgan et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS