Role of immune reactions in drug-induced liver injury (DILI)

HLA-DQA1*02:01 Is a Major Risk Factor for Lapatinib-Induced Hepatotoxicity in Women With Advanced Breast Cancer

(2011) Colin F. Spraggs et al.   JOURNAL OF CLINICAL ONCOLOGY

Natural Killer Cells Mediate Severe Liver Injury in a Murine Model of Halothane Hepatitis

(2011) Christine M. Dugan et al.   TOXICOLOGICAL SCIENCES

Involvement of natural killer T cells in halothane-induced liver injury in mice

(2010) Linling Cheng et al.   BIOCHEMICAL PHARMACOLOGY

Quantitative analyses and transcriptomic profiling of circulating messenger RNAs as biomarkers of rat liver injury

(2010) Barbara A. Wetmore et al.   HEPATOLOGY

Polymerase γ Gene POLG determines the risk of sodium valproate-induced liver toxicity

(2010) Joanna D. Stewart et al.   HEPATOLOGY

Stimulation of human T cells with sulfonamides and sulfonamide metabolites

(2010) J. Luis Castrejon et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury

(2010) Peter T. Donaldson et al.   JOURNAL OF HEPATOLOGY

A Mouse Model of Severe Halothane Hepatitis Based on Human Risk Factors

(2010) C. M. Dugan et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury

(2010) Jonathan B Singer et al.   NATURE GENETICS

Idiosyncratic Drug-Induced Liver Injury and the Role of Inflammatory Stress with an Emphasis on an Animal Model of Trovafloxacin Hepatotoxicity

(2010) Patrick J. Shaw et al.   TOXICOLOGICAL SCIENCES

Metabolomics in Toxicology: Preclinical and Clinical Applications

(2010) D. G. Robertson et al.   TOXICOLOGICAL SCIENCES

Metabolic and Chemical Origins of Cross-Reactive Immunological Reactions to Arylamine Benzenesulfonamides: T-Cell Responses to Hydroxylamine and Nitroso Derivatives

(2009) J. Luis Castrejon et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

(2009) A. H. Harrill et al.   GENOME RESEARCH

Sulindac Metabolism and Synergy with Tumor Necrosis Factor-  in a Drug-Inflammation Interaction Model of Idiosyncratic Liver Injury

(2009) W. Zou et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A Study of the Specificity of Lymphocytes in Nevirapine-Induced Skin Rash

(2009) X. Chen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

Halothane-Induced Liver Injury is Mediated by Interleukin-17 in Mice

(2009) Eisuke Kobayashi et al.   TOXICOLOGICAL SCIENCES

The role of damage associated molecular pattern molecules in acetaminophen-induced liver injury in mice

(2009) Brittany V. Martin-Murphy et al.   TOXICOLOGY LETTERS

Interleukin 10 deficiency exacerbates halothane induced liver injury by increasing interleukin 8 expression and neutrophil infiltration

(2008) Dechun Feng et al.   BIOCHEMICAL PHARMACOLOGY

Adverse Drug Reactions With Halogenated Anesthetics

(2008) ED Kharasch   CLINICAL PHARMACOLOGY & THERAPEUTICS

Peroxidase-Mediated Bioactivation of Hydroxylated Metabolites of Carbamazepine and Phenytoin

(2008) W. Lu et al.   DRUG METABOLISM AND DISPOSITION

Mechanism of T cell tolerance induction by murine hepatic Kupffer cells

(2008) Qiang You et al.   HEPATOLOGY

Effect of polyI:C cotreatment on halothane-induced liver injury in mice

(2008) Linling Cheng et al.   HEPATOLOGY

Pathogenic role of natural killer T and natural killer cells in acetaminophen-induced liver injury in mice is dependent on the presence of dimethyl sulfoxide

(2008) Mary Jane Masson et al.   HEPATOLOGY

Hepatitis C is a predictor of acute liver injury among hospitalizations for acetaminophen overdose in the United States: A nationwide analysis

(2008) Geoffrey C. Nguyen et al.   HEPATOLOGY