A three step continuous flow synthesis of the biaryl unit of the HIV protease inhibitorAtazanavir

Continuous-Flow Synthesis of 1-Substituted Benzotriazoles from Chloronitrobenzenes and Amines in a CN Bond Formation/Hydrogenation/Diazotization/Cyclization Sequence

(2013) Mao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Applying Flow Chemistry: Methods, Materials, and Multistep Synthesis

(2013) D. Tyler McQuade et al.   JOURNAL OF ORGANIC CHEMISTRY

Pauson–Khand Reactions in a Photochemical Flow Microreactor

(2013) Keisuke Asano et al.   ORGANIC LETTERS

Flow Chemistry - A Key Enabling Technology for (Multistep) Organic Synthesis

(2012) Jens Wegner et al.   ADVANCED SYNTHESIS & CATALYSIS

On Being Green: Can Flow Chemistry Help?

(2012) Steven V. Ley   CHEMICAL RECORD

Copper(I)-Catalyzed Azide-Alkyne Cycloadditions in Microflow: Catalyst Activity, High-T Operation, and an Integrated Continuous Copper Scavenging Unit

(2012) Alvaro Carlos Varas et al.   ChemSusChem

A prototype continuous-flow liquid–liquid extraction system using open-source technology

(2012) Matthew O'Brien et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

An expeditious synthesis of imatinib and analogues utilising flow chemistry methods

(2012) Mark D. Hopkin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Continuous Multiple Liquid–Liquid Separation: Diazotization of Amino Acids in Flow

(2012) Dennis X. Hu et al.   ORGANIC LETTERS

Development of a Continuous Flow Scale-Up Approach of Reflux Inhibitor AZD6906

(2012) Tomas Gustafsson et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous Hydrolysis and Liquid–Liquid Phase Separation of an Active Pharmaceutical Ingredient Intermediate Using a Miniscale Hydrophobic Membrane Separator

(2012) Albert E. Cervera-Padrell et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Development and Scale-Up of a Continuous, High-Pressure, Asymmetric Hydrogenation Reaction, Workup, and Isolation

(2012) Martin D. Johnson et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Convergent, Kilogram Scale Synthesis of an Akt Kinase Inhibitor

(2012) Pintipa Grongsaard et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Two-Step Flow Synthesis of Biarylmethanes by Reductive Arylation of Tosylhydrazones

(2012) Lukas Kupracz et al.   Journal of Flow Chemistry

Deciding Whether To Go with the Flow: Evaluating the Merits of Flow Reactors for Synthesis

(2011) Ryan L. Hartman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ten key issues in modern flow chemistry

(2011) Jens Wegner et al.   CHEMICAL COMMUNICATIONS

Recent advances in micro reaction technology

(2011) Charlotte Wiles et al.   CHEMICAL COMMUNICATIONS

Cross-coupling in flow

(2011) Timothy Noël et al.   CHEMICAL SOCIETY REVIEWS

The Microwave-to-Flow Paradigm: Translating High-Temperature Batch Microwave Chemistry to Scalable Continuous-Flow Processes

(2011) Toma N. Glasnov et al.   CHEMISTRY-A EUROPEAN JOURNAL

Practical Synthesis of Photochromic Diarylethenes in Integrated Flow Microreactor Systems

(2011) Tatsuro Asai et al.   ChemSusChem

Heterogeneous Catalytic Hydrogenation Reactions in Continuous-Flow Reactors

(2011) Muhammad Irfan et al.   ChemSusChem

Continuous flow reactors: a perspective

(2011) Charlotte Wiles et al.   GREEN CHEMISTRY

Suzuki–Miyaura Cross-Coupling of Heteroaryl Halides and Arylboronic Acids in Continuous Flow

(2011) Timothy Noël et al.   ORGANIC LETTERS

Key Green Engineering Research Areas for Sustainable Manufacturing: A Perspective from Pharmaceutical and Fine Chemicals Manufacturers

(2011) Concepción Jiménez-González et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Little artifices of huge libraries: Secrets of parallel liquid-phase synthesis

(2011) E. V. Babaev   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

Packed-Bed Reactors for Continuous-Flow CN Cross-Coupling

(2010) John R. Naber et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A flow-based synthesis of Imatinib: the API of Gleevec

(2010) Mark D. Hopkin et al.   CHEMICAL COMMUNICATIONS

Automated Generation and Reactions of 3-Hydroxymethylindoles in Continuous-Flow Microreactors

(2010) Thomas Tricotet et al.   CHEMISTRY-A EUROPEAN JOURNAL

Green and Sustainable Chemical Synthesis Using Flow Microreactors

(2010) Jun-ichi Yoshida et al.   ChemSusChem

The flow synthesis of heterocycles for natural product and medicinal chemistry applications

(2010) Marcus Baumann et al.   MOLECULAR DIVERSITY

Safe and Reliable Synthesis of Diazoketones and Quinoxalines in a Continuous Flow Reactor

(2010) Laetitia J. Martin et al.   ORGANIC LETTERS

Continuous flow multi-step organic synthesis

(2010) Damien Webb et al.   Chemical Science

Fifteen years of HIV Protease Inhibitors: raising the barrier to resistance

(2009) Annemarie M.J. Wensing et al.   ANTIVIRAL RESEARCH

Atazanavir

(2009) Katherine F. Croom et al.   DRUGS

AIDS Treatment In Brazil: Impacts And Challenges

(2009) Amy Stewart Nunn et al.   HEALTH AFFAIRS

A survey of the syntheses of active pharmaceutical ingredients for antiretroviral drug combinations critical to access in emerging nations

(2008) Eloan dos Santos Pinheiro et al.   ANTIVIRAL RESEARCH

An Efficient and Practical Synthesis of the HIV Protease Inhibitor Atazanavir via a Highly Diastereoselective Reduction Approach

(2008) Xing Fan et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT