DNA secondary structures and epigenetic determinants of cancer genome evolution

A novel G-quadruplex motif modulates promoter activity of human thymidine kinase 1

(2010) Richa Basundra et al.   FEBS Journal

Structure, location and interactions of G-quadruplexes

(2010) Julian L. Huppert   FEBS Journal

Widespread and tissue specific age-related DNA methylation changes in mice

(2010) S. Maegawa et al.   GENOME RESEARCH

Guanine quadruplex DNA structure restricts methylation of CpG dinucleotides genome-wide

(2010) Rashi Halder et al.   Molecular BioSystems

Epigenetic Instability due to Defective Replication of Structured DNA

(2010) Peter Sarkies et al.   MOLECULAR CELL

Relationship between nucleosome positioning and DNA methylation

(2010) Ramakrishna K. Chodavarapu et al.   NATURE

The landscape of somatic copy-number alteration across human cancers

(2010) Rameen Beroukhim et al.   NATURE

Genome-wide DNA methylation profiles in precancerous conditions and cancers

(2009) Yae Kanai   CANCER SCIENCE

Non-B DNA structure-induced genetic instability and evolution

(2009) Junhua Zhao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

In Vitro Recombination Mediated by G-Quadruplexes

(2009) Francisco Boán et al.   CHEMBIOCHEM

The Importance of Negative Superhelicity in Inducing the Formation of G-Quadruplex and i-Motif Structures in the c-Myc Promoter: Implications for Drug Targeting and Control of Gene Expression

(2009) Daekyu Sun et al.   JOURNAL OF MEDICINAL CHEMISTRY

Stable G-quadruplexes are found outside nucleosome-bound regions

(2009) Han Min Wong et al.   Molecular BioSystems

Genome-wide analysis predicts DNA structural motifs as nucleosome exclusion signals

(2009) Kangkan Halder et al.   Molecular BioSystems

Complex landscapes of somatic rearrangement in human breast cancer genomes

(2009) Philip J. Stephens et al.   NATURE

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

(2009) Rafael A Irizarry et al.   NATURE GENETICS

Isolation of deletion alleles by G4 DNA-induced mutagenesis

(2009) Daphne B Pontier et al.   NATURE METHODS

Mechanisms of change in gene copy number

(2009) P. J. Hastings et al.   NATURE REVIEWS GENETICS

The UCSC Genome Browser database: update 2010

(2009) B. Rhead et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Analyses of Recombination Prone Regions Predict Role of DNA Structural Motif in Recombination

(2009) Prithvi Mani et al.   PLoS One

G-quadruplex structures: in vivo evidence and function

(2009) Hans J. Lipps et al.   TRENDS IN CELL BIOLOGY

Evolutionary Breakpoints in the Gibbon Suggest Association between Cytosine Methylation and Karyotype Evolution

(2009) Lucia Carbone et al.   PLoS Genetics

Mutagenic Capacity of Endogenous G4 DNA Underlies Genome Instability in FANCJ-Defective C. elegans

(2008) Evelien Kruisselbrink et al.   CURRENT BIOLOGY

Genome-wide mapping and characterization of hypomethylated sites in human tissues and breast cancer cell lines

(2008) Y.-J. Shann et al.   GENOME RESEARCH

Effect of O6-Methylguanine on the Stability of G-Quadruplex DNA

(2008) Chongkham S. Mekmaysy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Epigenetics of a tandem DNA repeat: chromatin DNaseI sensitivity and opposite methylation changes in cancers

(2008) Koji Tsumagari et al.   NUCLEIC ACIDS RESEARCH

In Vitro Analysis of Integrated Global High-Resolution DNA Methylation Profiling with Genomic Imbalance and Gene Expression in Osteosarcoma

(2008) Bekim Sadikovic et al.   PLoS One

Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers

(2008) R. J. Leary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE