Cardiac valve cells and their microenvironment—insights from in vitro studies
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Title
Cardiac valve cells and their microenvironment—insights from in vitro studies
Authors
Keywords
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Journal
Nature Reviews Cardiology
Volume 11, Issue 12, Pages 715-727
Publisher
Springer Nature
Online
2014-10-14
DOI
10.1038/nrcardio.2014.162
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Note: Only part of the references are listed.- Immunogenicity in xenogeneic scaffold generation: Antigen removal vs. decellularization
- (2014) Maelene L. Wong et al. Acta Biomaterialia
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- (2013) Mehmet H. Kural et al. BIOMATERIALS
- Hemodynamic and Cellular Response Feedback in Calcific Aortic Valve Disease
- (2013) Sarah T. Gould et al. CIRCULATION RESEARCH
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- (2010) Fei Liu et al. JOURNAL OF CELL BIOLOGY
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- (2010) Yue-Hui Zhang et al. MATRIX BIOLOGY
- Therapeutic cell engineering with surface-conjugated synthetic nanoparticles
- (2010) Matthias T Stephan et al. NATURE MEDICINE
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- (2010) P. M. Gilbert et al. SCIENCE
- Integrins and Extracellular Matrix in Mechanotransduction
- (2010) M. A. Schwartz Cold Spring Harbor Perspectives in Biology
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- Bioengineering Challenges for Heart Valve Tissue Engineering
- (2009) Michael S. Sacks et al. Annual Review of Biomedical Engineering
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- Statins Block Calcific Nodule Formation of Valvular Interstitial Cells by Inhibiting α-Smooth Muscle Actin Expression
- (2009) Julie A. Benton et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
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- (2009) Julie A. Benton et al. BIOMATERIALS
- In situ elasticity modulation with dynamic substrates to direct cell phenotype
- (2009) April M. Kloxin et al. BIOMATERIALS
- Hydrogels as extracellular matrix mimics for 3D cell culture
- (2009) Mark W. Tibbitt et al. BIOTECHNOLOGY AND BIOENGINEERING
- Heart Valve Development
- (2009) Michelle D. Combs et al. CIRCULATION RESEARCH
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- (2009) Xiaoping Yang et al. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
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- The Extracellular Matrix: Not Just Pretty Fibrils
- (2009) R. O. Hynes SCIENCE
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- (2008) M. Pho et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- The effect of bioactive hydrogels on the secretion of extracellular matrix molecules by valvular interstitial cells
- (2008) Darshita N. Shah et al. BIOMATERIALS
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- (2008) Valery Krizhanovsky et al. CELL
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- (2008) G JENKINS INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Bone regulatory factors NFATc1 and Osterix in human calcific aortic valves
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- Characterization of High Affinity Binding Motifs for the Discoidin Domain Receptor DDR2 in Collagen
- (2008) Antonios D. Konitsiotis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of valvular interstitial cell calcification by components of the extracellular matrix
- (2008) Karien J. Rodriguez et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Dysregulation of Antioxidant Mechanisms Contributes to Increased Oxidative Stress in Calcific Aortic Valvular Stenosis in Humans
- (2008) Jordan D. Miller et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- 2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
- (2008) Robert O. Bonow et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
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