Redirecting Valvular Myofibroblasts into Dormant Fibroblasts through Light-mediated Reduction in Substrate Modulus

The mechanical memory of lung myofibroblasts

(2012) Jenna L. Balestrini et al.   Integrative Biology

Hepatic stellate cells require a stiff environment for myofibroblastic differentiation

(2011) Abby L. Olsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Genomic Differences Distinguish the Myofibroblast Phenotype of Distal Lung Fibroblasts from Airway Fibroblasts

(2011) Xiuxia Zhou et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Calcific Aortic Valve Disease: Not Simply a Degenerative Process

(2011) Nalini M. Rajamannan et al.   CIRCULATION

Cell–Matrix Interactions in the Pathobiology of Calcific Aortic Valve Disease

(2011) Jan-Hung Chen et al.   CIRCULATION RESEARCH

The role of cell plasticity in progression and reversal of renal fibrosis

(2011) Jean-Claude Dussaule et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases

(2011) Jeffrey L. Barnes et al.   KIDNEY INTERNATIONAL

Idiopathic pulmonary fibrosis

(2011) Talmadge E King et al.   LANCET

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Combining Dynamic Stretch and Tunable Stiffness to Probe Cell Mechanobiology In Vitro

(2011) Angela M. Throm Quinlan et al.   PLoS One

Mechanisms of pathological scarring: Role of myofibroblasts and current developments

(2011) Vincent Sarrazy et al.   WOUND REPAIR AND REGENERATION

β-Catenin Mediates Mechanically Regulated, Transforming Growth Factor-β1–Induced Myofibroblast Differentiation of Aortic Valve Interstitial Cells

(2010) Jan-Hung Chen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cardiac fibroblast to myofibroblast differentiation in vivo and in vitro: Expression of focal adhesion components in neonatal and adult rat ventricular myofibroblasts

(2010) Jon-Jon Santiago et al.   DEVELOPMENTAL DYNAMICS

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

(2010) Fei Liu et al.   JOURNAL OF CELL BIOLOGY

Micropatterned Dynamically Adhesive Substrates for Cell Migration

(2010) Srivatsan Raghavan et al.   LANGMUIR

Substrate stiffness regulates apoptosis and the mRNA expression of extracellular matrix regulatory genes in the rat annular cells

(2010) Yue-Hui Zhang et al.   MATRIX BIOLOGY

Synthesis of photodegradable hydrogels as dynamically tunable cell culture platforms

(2010) April M Kloxin et al.   Nature Protocols

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

(2010) P. M. Gilbert et al.   SCIENCE

Engineered materials and the cellular microenvironment: a strengthening interface between cell biology and bioengineering

(2010) Colin K. Choi et al.   TRENDS IN CELL BIOLOGY

Calcification by Valve Interstitial Cells Is Regulated by the Stiffness of the Extracellular Matrix

(2009) Cindy Ying Yin Yip et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Characterization of valvular interstitial cell function in three dimensional matrix metalloproteinase degradable PEG hydrogels

(2009) Julie A. Benton et al.   BIOMATERIALS

Functional PEG–peptide hydrogels to modulate local inflammation inducedby the pro-inflammatory cytokine TNFα

(2009) Chien-Chi Lin et al.   BIOMATERIALS

In situ elasticity modulation with dynamic substrates to direct cell phenotype

(2009) April M. Kloxin et al.   BIOMATERIALS

The myofibroblast: Paradigm for a mechanically active cell

(2009) Boris Hinz   JOURNAL OF BIOMECHANICS

Regulating MCP-1 diffusion in affinity hydrogels for enhancing immuno-isolation

(2009) Chien-Chi Lin et al.   JOURNAL OF CONTROLLED RELEASE

Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties

(2009) April M. Kloxin et al.   SCIENCE

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

(2009) D. E. Discher et al.   SCIENCE

Cofilin is a marker of myofibroblast differentiation in cells from porcine aortic cardiac valves

(2008) M. Pho et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Regulation and function of connective tissue growth factor/CCN2 in tissue repair, scarring and fibrosis

(2008) Xu Shi-Wen et al.   CYTOKINE & GROWTH FACTOR REVIEWS