Iron-Oxide-Based Nanovector for Tumor Targeted siRNA Delivery in an Orthotopic Hepatocellular Carcinoma Xenograft Mouse Model

Hepatobiliary Cancers

(2017) Al B. Benson et al.   Journal of the National Comprehensive Cancer Network

3D Porous Chitosan–Alginate Scaffolds as an In Vitro Model for Evaluating Nanoparticle-Mediated Tumor Targeting and Gene Delivery to Prostate Cancer

(2015) Kui Wang et al.   BIOMACROMOLECULES

Nanoparticle mediated silencing of DNA repair sensitizes pediatric brain tumor cells to γ-irradiation

(2015) Forrest M. Kievit et al.   Molecular Oncology

Superparamagnetic iron oxide nanoparticles mediated 131I-hVEGF siRNA inhibits hepatocellular carcinoma tumor growth in nude mice

(2014) Jing Chen et al.   BMC CANCER

Glypican-3-Targeted 89Zr PET Imaging of Hepatocellular Carcinoma

(2014) J. G. Sham et al.   JOURNAL OF NUCLEAR MEDICINE

Glypican-3-Targeting F(ab')2 for 89Zr PET of Hepatocellular Carcinoma

(2014) J. G. Sham et al.   JOURNAL OF NUCLEAR MEDICINE

In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer

(2014) Ramona Rudalska et al.   NATURE MEDICINE

Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice

(2014) Roman L. Bogorad et al.   Nature Communications

Treatment of glioblastoma multiforme using a combination of small interfering RNA targeting epidermal growth factor receptor and β-catenin

(2013) Kui Wang et al.   JOURNAL OF GENE MEDICINE

Knockdown of β-catenin with Dicer-Substrate siRNAs Reduces Liver Tumor Burden In vivo

(2013) Henryk Dudek et al.   MOLECULAR THERAPY

Cationic lipid nanoparticles for therapeutic delivery of siRNA and miRNA to murine liver tumor

(2013) Shu-hao Hsu et al.   Nanomedicine-Nanotechnology Biology and Medicine

An RGD-Modified MRI-Visible Polymeric Vector for Targeted siRNA Delivery to Hepatocellular Carcinoma in Nude Mice

(2013) Chun Wu et al.   PLoS One

First-in-Humans Trial of an RNA Interference Therapeutic Targeting VEGF and KSP in Cancer Patients with Liver Involvement

(2013) Josep Tabernero et al.   Cancer Discovery

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

A biomimetic nanovector-mediated targeted cholesterol-conjugated siRNA delivery for tumor gene therapy

(2012) Yang Ding et al.   BIOMATERIALS

Sorafenib for Treatment of Hepatocellular Carcinoma: A Systematic Review

(2012) Bingru Xie et al.   DIGESTIVE DISEASES AND SCIENCES

Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: Subanalyses of a phase III trial

(2012) Jordi Bruix et al.   JOURNAL OF HEPATOLOGY

Hepatocellular carcinoma

(2012) Alejandro Forner et al.   LANCET

Medical therapies for hepatocellular carcinoma: a critical view of the evidence

(2012) Augusto Villanueva et al.   Nature Reviews Gastroenterology & Hepatology

Nanoparticle ζ -Potentials

(2011) Tennyson L. Doane et al.   ACCOUNTS OF CHEMICAL RESEARCH

Surface Engineering of Iron Oxide Nanoparticles for Targeted Cancer Therapy

(2011) Forrest M. Kievit et al.   ACCOUNTS OF CHEMICAL RESEARCH

Gadolinium-loaded polymeric nanoparticles modified with Anti-VEGF as multifunctional MRI contrast agents for the diagnosis of liver cancer

(2011) Yongjun Liu et al.   BIOMATERIALS

Multifunctional quantum-dot-based siRNA delivery for HPV18 E6 gene silence and intracellular imaging

(2011) Jin-Ming Li et al.   BIOMATERIALS

Nanoparticle PEGylation for imaging and therapy

(2011) Jesse V Jokerst et al.   Nanomedicine

Hepatocellular Carcinoma

(2011) Hashem B. El-Serag   NEW ENGLAND JOURNAL OF MEDICINE

PEG-Mediated Synthesis of Highly Dispersive Multifunctional Superparamagnetic Nanoparticles: Their Physicochemical Properties and Function In Vivo

(2010) Conroy Sun et al.   ACS Nano

Chlorotoxin Labeled Magnetic Nanovectors for Targeted Gene Delivery to Glioma

(2010) Forrest M. Kievit et al.   ACS Nano

A Nanoparticle Size Series for In Vivo Fluorescence Imaging

(2010) Zoran Popović et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chlorotoxin bound magnetic nanovector tailored for cancer cell targeting, imaging, and siRNA delivery

(2010) Omid Veiseh et al.   BIOMATERIALS

Targeting of drugs and nanoparticles to tumors

(2010) Erkki Ruoslahti et al.   JOURNAL OF CELL BIOLOGY

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

RNA Interference as Therapeutics for Hepatocellular Carcinoma

(2010) Chuanrui Xu et al.   Recent Patents on Anti-Cancer Drug Discovery

PEI-PEG-Chitosan-Copolymer-Coated Iron Oxide Nanoparticles for Safe Gene Delivery: Synthesis, Complexation, and Transfection

(2009) Forrest M. Kievit et al.   ADVANCED FUNCTIONAL MATERIALS

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Functionalized Nanoparticles with Long-Term Stability in Biological Media

(2009) Chen Fang et al.   Small

An Oncogenomics-Based In Vivo RNAi Screen Identifies Tumor Suppressors in Liver Cancer

(2008) Lars Zender et al.   CELL

Therapeutic Nanoparticles for Drug Delivery in Cancer

(2008) K. Cho et al.   CLINICAL CANCER RESEARCH

Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect

(2008) H. Maeda et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Identification of metastasis-related microRNAs in hepatocellular carcinoma

(2008) Anuradha Budhu et al.   HEPATOLOGY

In vivotargeted gene delivery by cationic nanoparticles for treatment of hepatocellular carcinoma

(2008) Sonsoles Díez et al.   JOURNAL OF GENE MEDICINE

Sorafenib in Advanced Hepatocellular Carcinoma

(2008) Josep M. Llovet et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sorafenib in Liver Cancer — Just the Beginning

(2008) Lewis R. Roberts   NEW ENGLAND JOURNAL OF MEDICINE